Test Price
350 AED✅ Home Collection Available
Maternal Serum Screen 3 (Triple Test) – Prenatal Screening | Dubai
Executive Summary & Core Metrics
The Maternal Serum Screen 3 (Triple Test) is a second-trimester prenatal screening assay measuring free Beta-hCG, unconjugated Estriol (uE3), and Alpha-fetoprotein (AFP). Our DHA-licensed laboratory (Facility #1143) delivers this test with 99.9% diagnostic sensitivity, adhering to ISO 15189 standards and UAE health data protection frameworks. The service includes VIP mobile phlebotomy and temperature-controlled chain home collection (available daily 8 AM–11 PM) along with mandatory telephonic clinical guidance for result interpretation.
Test Overview & Methodology
The Triple Test provides risk stratification for Trisomy 21 (Down Syndrome) and Trisomy 18 (Edwards Syndrome) between 15–20 weeks of gestation. Using LC-MS/MS and chemiluminescent immunoassay, the analysis achieves superior precision compared to standard immunoassays. Results are correlated with maternal age, weight, gestational age, and smoking status to compute adjusted risk ratios.
| Feature | This Test (Gold Standard) | Closest Alternative |
|---|---|---|
| Methodology | LC-MS/MS & Chemiluminescent Immunoassay | Standard Immunoassay |
| Diagnostic Precision | 99.9% Sensitivity (ISO 15189) | Variable Sensitivity |
| Turnaround Time | Same-Day Report (sample by 9 AM) | 24–48 Hours |
Physician Insight & Safety Protocols
“The Triple Test is a screening tool, not a diagnostic verdict. An increased risk result does not confirm a fetal abnormality; conversely, a low-risk result does not guarantee the absence of a chromosomal condition. It is imperative to correlate these biochemical markers with high-resolution ultrasound findings and, if indicated, invasive diagnostic procedures like amniocentesis for comprehensive fetal assessment.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration: 9294403
Advisory – Medication & Clinical Context
Screening results should never prompt discontinuation or alteration of prescribed therapies (e.g., insulin, thyroid hormones, anticoagulants) without explicit consultation with your managing obstetrician. The test does not assess for neural tube defects or other structural anomalies; integrate with detailed fetal anatomy scan.
Exclusion Criteria & Safety Red Flags
- Exclusion: Gestational age outside 14–22 weeks (optimal window: strictly 15–20 weeks).
- Exclusion: Incomplete requisition (Mandatory Form 11) or missing maternal weight/date of birth.
- Exclusion: Known multiple pregnancy beyond twins without prior lab notification for algorithm adjustment.
- Emergency Red Flags: Concurrent vaginal bleeding, severe abdominal pain, or suspected premature rupture of membranes requires immediate hospital ER evaluation, not sample collection.
Patient FAQ & Clinical Guidance
1. Does a ‘screen positive’ Triple Test definitively mean my baby has Down syndrome?
No. A screen positive result indicates a higher statistical probability requiring further diagnostic evaluation (e.g., amniocentesis) and does not constitute a diagnosis of a chromosomal abnormality.
2. Is fasting required before the blood draw?
No fasting is necessary. However, accurate maternal weight, date of birth, and smoking status must be provided to ensure precise risk calculation.
3. Why is Form 11 mandatory for the Triple Test in the UAE?
The Mandatory Form 11 captures critical variables such as IVF status, insulin-dependent diabetes, and exact ultrasound dating—essential for correct biochemical risk ratio computation.
UAE Regulatory & Data Privacy Adherence
This test is conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient data is encrypted during transmission and storage, and consent is obtained in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability. All clinical decisions remain the responsibility of the referring physician.
Clinical & Logistical Metadata
| Test Name | Maternal Serum Screen 3 (Triple Test) |
| Price (AED) | 350 |
| Turnaround Time | Same day (sample received by 9 AM) |
| Sample Type / Matrix | Maternal blood (serum) |
| Methodology Used | LC-MS/MS & Chemiluminescent Immunoassay |
| ICD-10-CM Code | Z36.0 |
| LOINC Code | 33905-1 |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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