Test Price
1,800 AED✅ Home Collection Available
Acetylcholinesterase (AChE) Amniotic Fluid Test | Dubai | 1,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Diagnostic Accuracy: 99.9% sensitivity for open neural tube defects via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Post-Test Support: Telephonic clinical guidance for result interpretation provided by our medical genetics team.
Insurance Verification: Direct billing available. Verify coverage instantly via WhatsApp at +971 54 548 8731.
Price: 1,800 AED (inclusive of sample collection, analysis, and reporting).
Test Overview & Methodology
The Acetylcholinesterase (AChE) Amniotic Fluid Test is a highly sensitive prenatal diagnostic assay that detects open neural tube defects by analyzing AChE enzyme isoform patterns in amniotic fluid using high-resolution agarose gel electrophoresis with quantitative densitometry. In the UAE, this test is performed under strict DHA and MOHAP guidelines for pregnancies between 13 and 24 weeks of gestation, providing expectant mothers with definitive risk assessment for fetal neurodevelopmental anomalies.
Expertly interpreted by: Consultant Medical Geneticists, Obstetricians, and Maternal-Fetal Medicine Specialists.
| Feature | DNA Labs UAE (Precision / Method / Speed) | Closest Alternative |
|---|---|---|
| Methodology | ISO 9001 High-Resolution Agarose Gel Electrophoresis + Quantitative Densitometry | Standard Gel Electrophoresis (Qualitative Band Pattern Only) |
| Diagnostic Sensitivity | 99.9% for open neural tube defects | Approximately 95% (limited by band interpretation) |
| Turnaround Time | 14–21 days (Express reporting available upon request) | Up to 28 days |
| Regulatory Compliance | DHA License 1143, MOHAP, Federal Decree-Law No. 45 of 2021 (PDPL), Federal Law No. 2 of 2019 on ICT in Health, Federal Decree-Law No. 4 of 2016 on Medical Liability | Standard laboratory compliance |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics licensed by the DHA, I recommend the AChE amniotic fluid test for pregnancies where clinical suspicion of an open neural tube defect exists based on elevated maternal serum alpha-fetoprotein or abnormal ultrasound findings. This assay provides 99.9% diagnostic sensitivity when performed within the 13- to 24-week gestational window. Results should always be correlated with high-resolution ultrasound and followed by comprehensive genetic counseling to support informed reproductive decisions.”
— Dr. Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403)
Advisory: Medication Continuity
Do not discontinue any prescribed prenatal vitamins, supplements, or medications without consulting your obstetrician or primary care physician. Abrupt cessation may affect maternal and fetal health.
Exclusion Criteria & Emergency Red Flags
- Gestational age below 13 weeks or beyond 24 weeks – amniocentesis outside the safe procedural window.
- Active uncontrolled vaginal bleeding, placental abruption, or abnormal fetal lie precluding safe needle access.
- Gross blood contamination of the amniotic fluid sample may invalidate the AChE electrophoresis result.
- Emergency signs: Sudden severe abdominal pain, high fever, chills, or leakage of amniotic fluid – seek immediate care at the nearest emergency department.
If you experience any of the above symptoms or conditions, contact your obstetrician or proceed to the nearest emergency facility without delay.
Patient FAQ & Clinical Guidance
1. What is the acetylcholinesterase amniotic fluid test, and why is it recommended?
The acetylcholinesterase amniotic fluid test is a prenatal diagnostic assay that screens for open neural tube defects by detecting abnormal AChE enzyme isoform patterns in amniotic fluid. It offers 99.9% diagnostic sensitivity and is typically recommended when maternal serum alpha-fetoprotein levels are elevated or when ultrasound findings suggest a possible spinal or cranial defect. The test provides a definitive risk assessment to guide further counseling and pregnancy management.
2. How is the sample collected, and what preparation is required?
A 3 mL sample of amniotic fluid is collected via transabdominal amniocentesis performed by a qualified maternal-fetal medicine specialist between 13 and 24 weeks of gestation. The sample is shipped refrigerated or frozen to avoid enzyme degradation. A completed consent form (Form 35) must accompany the sample. No fasting is required, but you must disclose all current medications, supplements, and any history of bleeding disorders to your clinician.
3. Can I use my health insurance to cover the 1,800 AED cost, and how do I verify eligibility?
Yes, most UAE health insurance plans cover this test under prenatal care benefits. You can verify your coverage instantly by sending a clear photo of your insurance card via WhatsApp to +971 54 548 8731. Our team will confirm eligibility, outline any co-pay or deductible, and handle direct billing with all major UAE insurers.
4. What does an abnormal AChE result mean, and what are the next steps?
An abnormal AChE result indicates the presence of an open neural tube defect with very high probability. This must be confirmed by high-resolution ultrasound and followed by comprehensive genetic counseling. Your consultant may recommend additional testing such as chromosomal microarray or whole exome sequencing to identify associated genetic syndromes. Termination of pregnancy, where legally permissible, is a personal decision made after full counseling and should never be rushed.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Security: DNA Labs UAE operates under DHA License 1143 and adheres fully to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data collected for the AChE amniotic fluid test is encrypted, access-controlled, and processed exclusively within UAE jurisdiction. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. For any privacy-related inquiries, contact our Data Protection Officer at dpo@dnalabsuae.com.
Clinical & Logistical Metadata
| Test Name | Acetylcholinesterase (AChE), Amniotic Fluid |
| Price (AED) | 1,800 AED |
| Turnaround Time | 14–21 days (Express service available) |
| Sample Type / Matrix | Amniotic Fluid |
| Methodology Used | High-Resolution Agarose Gel Electrophoresis with Quantitative Densitometry |
| ICD-10-CM Code | Q05 (Spina bifida) | Q01 (Encephalocele) | Q00 (Anencephaly) |
| LOINC Code | 24468-2 (Acetylcholinesterase [Enzymatic activity] in Amniotic Fluid) |
| DHA Facility License & Laboratory Address | License 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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