Test Price
280 AED✅ Home Collection Available
Maternal Serum Screen 2 Dual Test (First Trimester Combined Screening) in UAE | 280 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance for result interpretation by DHA-licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The Maternal Serum Screen 2 Dual Test (First Trimester Combined Screening) quantifies pregnancy-associated plasma protein-A (PAPP-A) and free beta-human chorionic gonadotropin (free β-hCG) in maternal serum, enabling early risk assessment for trisomies 21, 18, and 13. This UAE-based protocol combines advanced chemiluminescent immunoassay with nuchal translucency ultrasound findings to achieve superior detection rates.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Methodology | Enhanced Chemiluminescent Immunoassay (ECLIA) | Manual CLIA / ELISA |
| Analytical Sensitivity | 99.9% (PAPP‑A / free β‑hCG) | ~95% |
| Reporting Speed | Same Day (sample received by 9 AM) | 2‑3 working days |
| DHA Compliance | Full DHA/MOHAP Guidelines | May not reflect latest algorithm updates |
| Integrated Risk Calculation | Combined with NT ultrasound, maternal age, weight, diabetes, IVF | Basic software, fewer covariates |
Physician Insight & Safety Protocols
Advisory: Medication and Supplement Use
Do not discontinue prescribed medication without consulting your doctor. Additionally, avoid biotin supplements exceeding 5 mg/day for 72 hours prior to blood draw as they may interfere with the assay.
Exclusion Criteria & Red Flags
- Gestation outside valid window (<9 weeks or >13 weeks +6 days).
- Multiple pregnancies with more than two fetuses (separate protocol required).
- Red Flag: A screen‑positive result indicates increased risk, not a diagnosis – it necessitates confirmatory invasive testing (CVS/amniocentesis).
- Red Flag: Maternal conditions (insulin‑dependent diabetes, IVF conception, smoking, BMI >40) may affect marker levels; ensure all details are provided on Form 11.
- Recent use of biotin supplements (>5 mg/day) within 72 hours may interfere – discontinue before draw.
Patient FAQ & Clinical Guidance
1. What is the First Trimester Dual Marker Test?
The Dual Marker test measures PAPP-A and free beta-hCG in maternal blood to assess chromosomal abnormality risk between 9–13 weeks. It forms the biochemical arm of combined screening, used with nuchal translucency ultrasound to calculate a personalized risk score for trisomy 21, 18, and 13.
2. How accurate is this test for Down syndrome?
It detects approximately 85–90% of trisomy 21 cases with a 5% false-positive rate when combined with nuchal translucency ultrasound. The detection rate improves with high-quality sonography and exact maternal data; however, a positive screen always requires confirmatory diagnostic testing like CVS or amniocentesis.
3. How should I prepare for the test?
No fasting is required, but avoid biotin supplements 72 hours prior and provide accurate maternal history as listed. You must complete the Maternal Serum Screen Requisition Form (Form 11) with your date of birth, LMP/ultrasound dating, number of fetuses, diabetic status, body weight, IVF, smoking, and any history of trisomy 21 pregnancy. Our phlebotomist will collect 3 mL of blood in an SST tube under cold-chain conditions.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Legal Compliance
This service adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is handled under strict confidentiality.
Clinical testing safety and patient consent comply with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | Maternal Serum Screen 2 Dual Test (First Trimester Combined Screening) |
| Price (AED) | 280 |
| Turnaround Time | Same Day (sample received by 9 AM) |
| Sample Type / Matrix | Maternal Serum (Blood) |
| Methodology Used | Enhanced Chemiluminescent Immunoassay (ECLIA) |
| ICD-10-CM Code | Z13.79 |
| LOINC Code | 49566-4 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
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