PKD2 Gene Autosomal Dominant Polycystic Kidney Disease Type 2 (ADPKD2) Genetic Test in UAE | 2,800 AED

Executive Summary & Core Metrics

Diagnostic Sensitivity: 99.9% via ISO 9001:2015 certified Next‑Generation Sequencing (NGS) platform.
VIP Mobile Phlebotomy: Temperature‑controlled cold‑chain home collection available daily from 8 AM to 11 PM.
Post‑Test Counseling: Free genetic counseling session with a Consultant Medical Genetics.
Insurance Verification: Direct WhatsApp check at +971545488731.

Test Overview & Methodology

The PKD2 gene next‑generation sequencing test comprehensively analyzes all coding exons and splice‑site regions of the PKD2 gene to definitively diagnose autosomal dominant polycystic kidney disease type 2 (ADPKD2). This hereditary disorder leads to progressive renal cyst formation, hepatic cysts, and hypertension. Our NGS platform provides superior coverage compared to traditional methods, ensuring accurate detection of disease‑causing mutations.

Feature	Our Test (NGS Gold Standard)	Closest Alternative (Panel‑Based / Sanger)
Technology	Next‑Generation Sequencing (NGS)	Targeted mutation panel or single‑gene Sanger
Coverage	Full gene – coding exons, splice sites, deep intronic regions	Limited to pre‑selected hotspots
Turnaround Time	3–4 weeks	4–8 weeks
Price (AED)	2,800	1,800–2,500 (incomplete analysis)

Physician Insight & Safety Protocols

“A positive PKD2 variant confirms autosomal dominant polycystic kidney disease type 2, but clinical correlation with renal imaging and family pedigree remains essential. This test does not predict disease severity; regular nephrology follow‑up is mandatory. Do not discontinue prescribed antihypertensive or renal‑protective medications without direct physician consultation.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Medication Safety Advisory

Never alter prescribed medications (antihypertensives, tolvaptan, immunosuppressants) without explicit physician approval. Continue all medications as directed. This test is for diagnostic confirmation and does not replace ongoing medical management.

Exclusion Criteria & Red Flags

Exclusion criteria: Pregnancy or suspected pregnancy (requires specialist clearance), inability to provide 4 mL of whole blood, unavailability for pre-test genetic counseling, acute febrile illness.
Red flags requiring emergency room visit before testing: Sudden severe flank pain with hematuria, fever >38.5°C, signs of acute kidney injury, transient loss of consciousness.

Patient FAQ & Clinical Guidance

1. What is the PKD2 gene NGS test and why should I consider it?

This test reads the entire PKD2 gene sequence to detect disease‑causing mutations, confirming a clinical suspicion of ADPKD2 in at‑risk individuals or family members. It is recommended for individuals with a family history of polycystic kidney disease or those exhibiting renal cysts on imaging.

2. How accurate is this NGS‑based test for ADPKD2 diagnosis?

With a sensitivity of 99.9% and specificity near 100% for PKD2 coding variants, our NGS platform outperforms traditional methods, ensuring diagnostic confidence for UAE patients.

3. What sample is needed and how does the home collection service work?

A 4 mL whole blood sample (or DNA FTA card) is collected at your home by a DHA‑licensed phlebotomist between 8 AM and 11 PM; temperature‑controlled cold‑chain transport maintains sample integrity.

UAE Regulatory & Data Privacy Adherence

Data Privacy: All personal data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL). Health data processing complies with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient safety and consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.

Licensing: DHA Facility License No. 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.

Clinical & Logistical Metadata

Test Name	PKD2 Gene NGS – Autosomal Dominant Polycystic Kidney Disease Type 2 (ADPKD2)
Price (AED)	2,800
Turnaround Time	3–4 weeks
Sample Type / Matrix	Whole blood (4 mL) or DNA FTA card (buccal swab)
Methodology Used	Next-Generation Sequencing (NGS) – full gene sequencing with CNV detection
ICD-10-CM Code	Q61.2 (Polycystic kidney, adult type)
LOINC Code	81981-4
DHA Facility License & Laboratory Address	DHA License No. 1143 \| DNA Labs UAE \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE