PKD1 Gene Sequencing Test for Autosomal Dominant Polycystic Kidney Disease Type 1 (ADPKD1) in UAE | 2,800 AED

Executive Summary & Core Metrics

Accuracy Guarantee: >99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM.
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a Consultant Medical Geneticist.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Diagnostic Precision

The PKD1 Gene Sequencing Test is a comprehensive NGS-based analysis that detects pathogenic variants in the PKD1 gene, the most common cause of autosomal dominant polycystic kidney disease (ADPKD). This test provides definitive molecular diagnosis, enables pre-symptomatic screening, and guides personalized management and genetic counseling for affected families.

Feature	Our Test (PKD1 NGS)	Traditional Panel / Sanger
Methodology	NGS – full gene sequencing & CNV analysis	Limited target regions; no large deletions/duplications
Diagnostic Sensitivity	>99.9% for point mutations & structural variants	~85–90% for point mutations; misses large rearrangements
Turnaround Time	3–4 weeks	4–8 weeks (often batched)
Variant Interpretation	Clinically curated ACMG/AMP guidelines	Outdated databases; manual curation

Physician Insight & Safety Protocols

“A molecular diagnosis of ADPKD1 through comprehensive PKD1 sequencing offers families clarity and a foundation for informed reproductive and clinical decisions. This test must always be paired with expert genetic counseling and correlation with renal imaging for complete clinical context. Our role is to guide you through every step with precision and empathy.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

⚠ Medication Advisory

Do not alter or stop any prescribed treatment without direct consultation with your nephrologist. Genetic findings complement—but do not replace—ongoing renal management, blood pressure control, or other therapeutic interventions. All medication adjustments must be supervised by your treating physician.

Patient Safety: Exclusion Criteria & Emergency Red Flags

Exclusion Criteria

Testing minors without legal guardian consent (per Federal Decree-Law No. 4 of 2016 on Medical Liability)
Individuals unable to provide informed consent
Non‑medical, forensic, or paternity testing intent
Inadequate sample collection conditions (hemolysis, contamination, insufficient volume)

ER Red Flags – Seek Immediate Medical Attention

Sudden, severe flank or abdominal pain
Gross hematuria (visible blood in urine)
Acute onset of severe headache (suspected intracranial aneurysm)
Uncontrolled hypertension with neurological symptoms

Patient FAQ & Clinical Guidance

1. What is the clinical utility of the PKD1 genetic test?

Snippet: The PKD1 NGS test identifies disease‑causing mutations, enabling accurate diagnosis, pre‑symptomatic testing, and informed family planning for autosomal dominant polycystic kidney disease type 1. This empowers nephrologists to stratify risk, initiate early monitoring, and offer reproductive options through genetic counseling.

2. How is the sample collected, and is a hospital visit necessary?

Snippet: Our VIP mobile phlebotomy service collects a simple blood or buccal swab sample at your home or office, with cold‑chain logistics ensuring sample integrity from 8 AM to 11 PM. No hospital visit is required; a trained phlebotomist arrives with a sterile kit and completes the collection in under 10 minutes.

3. What is the turnaround time and reporting process?

Snippet: Results are delivered in 3 to 4 weeks in a secure, DHA‑compliant digital report, with optional telephonic post‑consultation from our clinical genetics team. The report includes variant classification, clinical significance, and recommendations for further clinical correlation with imaging and renal function.

UAE Regulatory & Data Privacy Adherence

DNA Labs UAE operates under DHA Facility License No. 1143 and strictly complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all patient data handling, storage, and sharing. All genetic test results are encrypted and accessible only to authorized healthcare providers with your explicit consent. Additionally, we adhere to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring secure electronic health records and telemedicine practices. Our laboratory processes are ISO 9001:2015 accredited, guaranteeing the highest standards of quality and confidentiality.

Clinical & Logistical Metadata

Test Name	PKD1 Gene Sequencing Test (ADPKD1)
Price (AED)	2,800 AED
Turnaround Time	3–4 Weeks
Sample Type / Matrix	Whole Blood or Buccal Swab
Methodology Used	Next-Generation Sequencing (NGS) – Full Gene Sequencing & CNV Analysis
ICD-10-CM Code	Q61.2
LOINC Code	94857-5
DHA Facility License & Laboratory Address	DHA License No: 1143 \| DNA Labs UAE \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE