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Test Price

2,800 AED

✅ Home Collection Available

MAX Gene (Pheochromocytoma Type 9) Mutation Analysis in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

This advanced genetic test utilises Next-Generation Sequencing (NGS) to detect pathogenic variants in the MAX gene, the primary cause of hereditary pheochromocytoma-type 9 and paraganglioma syndrome. The analysis delivers definitive risk assessment for personalised oncological surveillance and clinical management.

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all Emirates.
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The MAX gene NGS analysis provides comprehensive coverage of all coding exons and flanking intronic regions, with concurrent copy number variation (CNV) detection confirmed by MLPA. This single-assay approach eliminates the need for sequential testing and reduces turnaround time while maximising diagnostic yield for hereditary pheochromocytoma and paraganglioma susceptibility. The methodology is validated for both germline and tumour-derived DNA specimens.

Feature Our Test (NGS) Closest Alternative (Single-Gene Sanger + Panel)
Precision 99.9% analytical sensitivity & specificity for MAX ~98%, may miss large deletions or deep intronic variants
Method Full-gene NGS with CNV detection and MLPA confirmation PCR-based Sanger sequencing; CNV by separate MLPA
Turnaround Time 3 to 4 weeks 4 to 6 weeks (sequential assays)
Clinical Depth Comprehensive gene coverage + predisposition to paraganglioma Only targeted MAX exons; limited phenotypic context

Physician Insight & Safety Protocols

“As a consultant medical geneticist, I emphasize that a negative MAX NGS result does not exclude all hereditary tumour syndromes; comprehensive clinical evaluation and detailed family history remain essential. Molecular findings must always be correlated with biochemical testing and imaging, and therapeutic decisions should never be based solely on a genetic report.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Clinical Advisory

Do not discontinue, adjust, or initiate any medication—including antihypertensive or hormonal therapies—based solely on genetic test results without consulting your treating physician. All clinical actions must be guided by a complete endocrinological evaluation.

Exclusion Criteria & ER Red Flags

  • Acute hypertensive crisis or symptomatic catecholamine surge — seek emergency care immediately.
  • Inability to provide a valid blood or DNA sample (absolute contraindication).
  • Minors under 18 years without legal guardian consent and mandatory pre-test genetic counselling as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • Recent blood transfusion or allogeneic transplant may interfere with germline analysis; inform the laboratory team prior to sample collection.

Patient FAQ & Clinical Guidance

1. What is the MAX Gene Pheochromocytoma Type 9 Genetic Test and why is it priced at 2800 AED?

This test sequences the complete MAX gene using NGS to identify pathogenic variants that cause hereditary pheochromocytoma-type 9, a rare neuroendocrine tumour syndrome. The 2800 AED fee covers full gene sequencing, CNV analysis, clinical interpretation, and pre-test genetic counselling by a DHA-licensed consultant geneticist.

2. How is the sample collected and how long does it take to receive results?

Sample options include a standard venous blood draw, a dried blood spot on an FTA card, or extracted DNA. Our VIP Mobile Phlebotomy service collects at your home or workplace under temperature-controlled cold-chain conditions, available daily from 8 AM to 11 PM. Results are delivered within 3 to 4 weeks from sample receipt at the ISO-certified laboratory.

3. Is this test covered by UAE insurance and do you offer home collection?

Yes, direct billing verification is available through WhatsApp at +971 54 548 8731. Our service includes ISO-certified cold-chain home collection across all Emirates, ensuring specimen integrity from your doorstep to the laboratory.

UAE Regulatory & Data Privacy Adherence

This diagnostic service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-controlled, and processed exclusively within secure UAE-based infrastructure. Patient consent for genetic analysis and data handling is obtained prior to sample collection in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.

Clinical & Logistical Metadata

Test Name MAX Gene (Pheochromocytoma Type 9) Mutation Analysis – NGS
Price (AED) 2,800 AED
Turnaround Time 3 to 4 weeks
Sample Type / Matrix Peripheral whole blood (EDTA), dried blood spot on FTA card, or extracted genomic DNA
Methodology Used Next-Generation Sequencing (NGS) with CNV detection and MLPA confirmation
ICD-10-CM Code Z15.09 (Genetic susceptibility to other malignant neoplasm)
LOINC Code 21636-0 (Gene analysis)
DHA Facility License & Laboratory Address DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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All reports reviewed by DHA-Certified physicians