Oncomine Myeloproliferative Neoplasm MPN Panel Test Price 8190 AED

Introduction

Myeloproliferative neoplasms (MPNs) are a group of blood cancers characterized by the overproduction of blood cells in the bone marrow. Early and accurate diagnosis is crucial for effective treatment and management of these conditions. The Oncomine Myeloproliferative Neoplasm (MPN) Panel Test is an advanced genetic test designed to identify specific mutations associated with MPNs. For people in the UAE, understanding this test can help in managing and treating MPNs effectively.

Symptoms of Myeloproliferative Neoplasms

Recognizing the symptoms of MPNs is essential for early detection and diagnosis. Common symptoms associated with MPNs include:

1. Fatigue: Persistent tiredness and lack of energy, often severe enough to interfere with daily activities.
2. Bleeding or Bruising Easily: Unexplained bruises or prolonged bleeding from minor cuts can be a sign of blood disorders.
3. Enlarged Spleen: Discomfort or a feeling of fullness in the left upper abdomen due to an enlarged spleen.
4. Frequent Infections: Increased susceptibility to infections as a result of abnormal blood cell production.
5. Night Sweats: Excessive sweating during the night, often soaking through sleepwear.
6. Bone Pain: Pain or tenderness in the bones, which can occur due to the overproduction of blood cells.
7. Weight Loss: Unintended weight loss and loss of appetite.
8. Shortness of Breath: Difficulty breathing, especially during physical activity.

Components of the Oncomine Myeloproliferative Neoplasm (MPN) Panel Test

The Oncomine MPN Panel Test is a comprehensive genetic test that involves several key components to ensure accurate identification of mutations associated with MPNs:

1. Blood or Bone Marrow Sample Collection: A sample of blood or bone marrow is collected from the patient. This sample contains DNA that will be analyzed for genetic mutations.
2. Next-Generation Sequencing (NGS) Technology: The test uses advanced NGS technology to analyze the DNA from the collected sample. This technology allows for the simultaneous examination of multiple genes associated with MPNs.
3. Targeted Gene Panel: The Oncomine MPN Panel specifically targets genes known to be involved in MPNs, such as JAK2, CALR, and MPL. Mutations in these genes are commonly associated with different types of MPNs.
4. Bioinformatics Analysis: Sophisticated bioinformatics tools are used to interpret the sequencing data, identifying specific mutations and providing a comprehensive genetic profile of the patient’s sample.

Test Details

1. The Oncomine Myeloproliferative Neoplasm (MPN) Panel Test is a diagnostic tool that is used to detect genetic mutations associated with MPN. This panel test analyzes 35 genes that are frequently mutated in MPN, including JAK2, CALR, and MPL.
2. MPN is a group of blood disorders that cause the bone marrow to produce too many blood cells. This can lead to a range of symptoms, including fatigue, weakness, and an enlarged spleen. MPN can also increase the risk of blood clots and other complications.
3. The Oncomine MPN Panel Test is performed using a small sample of blood or bone marrow. The test uses advanced sequencing technology to identify genetic mutations that may be causing the patient’s MPN. The results of the test can help guide treatment decisions and provide important information about the patient’s prognosis.
4. Overall, the Oncomine MPN Panel Test is a valuable tool for diagnosing and managing MPN, and it can help improve outcomes for patients with this challenging condition.

Importance of the Oncomine MPN Panel Test

The Oncomine MPN Panel Test offers several significant benefits for patients and healthcare providers:

1. Accurate Diagnosis: By identifying specific genetic mutations, the test provides a precise diagnosis, distinguishing between different types of MPNs.
2. Personalized Treatment: The detailed genetic profile allows for personalized treatment plans, targeting the specific mutations and improving treatment outcomes.
3. Early Detection: The test enables early detection of MPNs, allowing for timely intervention and better disease management.
4. Monitoring Disease Progression: The test can be used to monitor disease progression and response to treatment, helping to adjust therapeutic strategies as needed.

Conclusion

The Oncomine Myeloproliferative Neoplasm (MPN) Panel Test is an advanced diagnostic tool essential for the accurate diagnosis and effective management of MPNs. For residents in the UAE, understanding the importance of this test, recognizing the symptoms of MPNs, and knowing the components and details of the test can lead to timely diagnosis and better disease management. If you experience symptoms suggestive of MPNs, consult with a healthcare provider about the Oncomine MPN Panel Test to ensure accurate diagnosis and appropriate treatment.

Test Name: ONCOMINE MYELOPROLIFERATIVE NEOPLASM MPN PANEL Test

Components: ABL1, ASXL1, CBL, CALR, DNMT3A, EZH2, ETV6, FLT3, IDH1, IDH2, IKZF1, JAK2, KIT, MPL, NPM1, NRAS, NF1, RUNX1, SF3B1, SRSF2, SH2B3, STAG2, TET2, TP53, U2AF1, ZRSR2

FUSION GENE: ETV6, JAK2, KMT2A, RUNX1

Price: 8190.0 AED

Sample Condition: 3 mL (2 mL min.) whole Blood OR Bone Marrow in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled NGS Test Requisition Form is mandatory.

Report Delivery: Sample by 1st / 16th of every month; Report 15th / 30th of Same month

Method: NGS

Test type: Leukemia

Doctor: Hematologist, Oncologist

Test Department: MOLECULAR DIAGNOSTICS

Pre Test Information: Duly filled NGS Test Requisition Form is mandatory.