Test Price
2,800 AED✅ Home Collection Available
SYNGAP1-Related Intellectual Disability (Autosomal Dominant Type 5) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين SYNGAP1 المرتبط بالإعاقة الذهنية (النوع 5 السائد جسديًا) في الإمارات | 2800 درهم | إرشادات هيئة الصحة بدبي 2026
ملخص تنفيذي
فحص وراثي دقيق بنسبة 99.9% عبر تقنية تسلسل الجيل التالي (NGS) لتشخيص الطفرات في جين SYNGAP1 المسبب للإعاقة الذهنية السائدة جسديًا من النوع الخامس. يتم التحليل في مختبر معتمد وفق ISO 9001:2015، مع خدمة سحب منزلي للمرضى على مستوى الإمارات، ودعم سريري بعد النتيجة. ضمان التزام كامل بقانون البيانات الصحية الاتحادي رقم 41 لسنة 2024 ولوائح هيئة الصحة بدبي.
Clinical & Service Executive Summary
- Diagnostic Accuracy: 99.9% analytical sensitivity and specificity via ISO-certified NGS processing.
- Premium Logistics: Hospital-grade ISO cold‑chain home collection (Dubai, Abu Dhabi, Sharjah, all Emirates) and VIP mobile phlebotomy service, 8 AM – 11 PM.
- Clinical Guidance: Complimentary post‑test telephonic clinical interpretation with a genetic counsellor.
- Insurance & Billing: Direct billing verification and pre‑approval support via WhatsApp at +971 54 548 8731.
Test Overview
The SYNGAP1 gene test utilises Next Generation Sequencing (NGS) to detect pathogenic variants in the SYNGAP1 gene, which is strongly associated with autosomal dominant intellectual disability type 5 (also termed SYNGAP1‑related developmental and epileptic encephalopathy). This investigation is the only definitive method to confirm the molecular diagnosis, guide targeted surveillance for associated epilepsy and autism spectrum disorder, and inform family recurrence risk.
(الفحص الجزيئي الوحيد لتأكيد تشخيص الإعاقة الذهنية المرتبطة بجين SYNGAP1 في الإمارات.)
| Feature | Our Test (SYNGAP1 NGS) | Closest Alternative (Chromosomal Microarray / CMA) |
|---|---|---|
| Precision Target | Single‑nucleotide variants, indels in SYNGAP1 with 99.9% sensitivity | Copy number variants only; misses ~85% of SYNGAP1 point mutations |
| Methodology | NGS with Sanger confirmation of pathogenic calls | Oligonucleotide array CGH |
| Turnaround Time | 3–4 weeks | 5–6 weeks |
| Cost (UAE) | 2800 AED | ~3500 AED |
Physician Insight & Safety Protocol
“While this NGS assay provides critical molecular confirmation, clinical correlation with developmental history and EEG findings remains essential. A negative result does not rule out other genetic aetiologies, and variant re‑classification may occur as knowledge evolves. Families should receive comprehensive genetic counselling before and after testing.” – Dr. Prabhakar Reddy, DHA: 61713011.
⚠ Medication & Safety Warning
Do not discontinue any prescribed medication (including antiepileptic drugs) without consulting your treating physician. This test does not replace ongoing neurological management.
- Exclusion Criteria: Known haematological disorder contraindicating venepuncture; inability to provide informed consent for genetic testing as per UAE CDS Law (Minors).
- ER Red Flags: Seek immediate medical attention if the patient develops new‑onset seizures, prolonged altered consciousness, or severe behavioural regression while awaiting results.
Frequently Asked Questions (FAQ)
What is the SYNGAP1 gene test, and why is it ordered?
This test sequences the entire coding region of the SYNGAP1 gene to identify pathogenic mutations causing intellectual disability and epilepsy. يفحص هذا الاختبار كامل المنطقة المشفرة لجين SYNGAP1 لتحديد الطفرات المسببة للإعاقة الذهنية والصرع.
How much does the SYNGAP1 NGS cost in Dubai / UAE, and is it covered by insurance?
The all‑inclusive price is 2800 AED; we offer direct insurance verification and can provide pre‑approval documentation before sample collection. السعر الشامل 2800 درهم؛ نقدم خدمة التحقق المباشر من التأمين ووثائق الموافقة المسبقة قبل سحب العينة.
What sample types are accepted, and how should the child be prepared?
We accept whole blood, extracted DNA, or a single drop of blood on an FTA card; a genetic counselling session to chart the family pedigree is mandatory before collection. نقبل الدم الكامل أو الحمض النووي المستخرج أو نقطة دم واحدة على بطاقة FTA؛ جلسة استشارة وراثية إلزامية لرسم شجرة العائلة قبل الجمع.
UAE Legal Compliance: This service fully adheres to Federal Decree‑Law No. 41 of 2024 on Health Data (Art. 87), the 2026 CDS Law for Minors, and the UAE Personal Data Protection Law (PDPL).
Quality Accreditation: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). Laboratory facility license: 9834453.
Support & Booking: Phone / WhatsApp +971 54 548 8731 (8 AM – 11 PM, daily). Direct billing verification available.
© 2026 — All clinical information is reviewed by DHA‑licensed neurologists and genetic counsellors. Last updated: April 2026.
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التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians