Test Price
2,800 AED✅ Home Collection Available
NDUFS8 Gene Leigh Syndrome Genetic Test in UAE | 2800 AED | DHA Compliant
Executive Summary & Core Metrics
Executive Summary: This advanced genetic test provides precise diagnosis for Leigh syndrome associated with the NDUFS8 gene, with 99.9% diagnostic sensitivity via ISO accredited processing. We ensure temperature-controlled cold-chain home collection, post-test clinical guidance, and direct insurance verification via WhatsApp.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The NDUFS8 Gene Leigh Syndrome Next-Generation Sequencing (NGS) test analyzes the entire coding region and splice sites of the NDUFS8 gene, detecting pathogenic variants associated with Leigh syndrome. This test provides comprehensive coverage for diagnosis, carrier screening, and family risk assessment with >99% detection rate for known and novel variants.
| Feature | Our NDUFS8 NGS Test | Alternative Single-Gene Test (Sanger) |
|---|---|---|
| Methodology | NGS (Next-Gen Sequencing) - full gene coverage | Sanger sequencing (limited to known variants) |
| Turnaround Time | 3 to 4 Weeks | 2 to 3 Weeks |
| Detection Rate | >99% of pathogenic variants | ~85% (misses deep intronic/novel variants) |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I emphasize that a genetic result must be interpreted within the full clinical context, including neurological examination, mitochondrial function studies, and family history. Do not alter any prescribed medication—especially metabolic supplements or anti-epileptic drugs—without direct supervision from your specialist, as abrupt changes can trigger metabolic decompensation.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Safety
Medication Warning:
Do not discontinue prescribed medication without consulting your doctor. Many treatments for mitochondrial disorders, including anti-epileptic drugs, cofactor supplements, and dietary therapies, are life-sustaining. Any changes must be medically supervised.
Exclusion Criteria & Red Flags
- Severe acute illness or metabolic crisis contraindicating blood draw.
- Uncontrolled seizures requiring immediate emergency care.
- Allergy to phlebotomy equipment (local anesthetic, antiseptic).
- If patient is unable to provide informed consent, a legally authorized guardian must consent per UAE law (Federal Decree-Law No. 4 of 2016 on Medical Liability).
- ER Red Flags: Sudden neurological decline, respiratory distress, lactic acidosis — seek immediate hospital care; genetic testing can be arranged after stabilization.
Patient FAQ & Clinical Guidance
1. What does a positive NDUFS8 gene variant mean for my child?
A positive result identifies a pathogenic mutation linked to Leigh syndrome, confirming the molecular diagnosis and enabling tailored management, prognosis, and family planning.
2. Can this test be done using a buccal swab instead of blood?
Yes, we accept DNA extracted from buccal swabs or dried blood spot cards (FTA), offering flexibility for pediatric patients. Our phlebotomists are trained in pediatric collection and cold-chain transport is ensured.
3. How long does it take to receive results and who will explain them?
Results are typically ready in 3 to 4 weeks and are delivered by a clinical geneticist or your referring neurologist during a post-test teleconsultation.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance
This test and associated data handling comply with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL)
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields
- Federal Decree-Law No. 4 of 2016 on Medical Liability
- DHA Standards for Genetic Testing and Laboratory Accreditation (ISO 15189)
All genetic data is encrypted, access-controlled, and processed under strict confidentiality. Consent for genetic testing is obtained in accordance with UAE law.
Clinical & Logistical Metadata
| Test Name | NDUFS8 Gene Leigh Syndrome Next-Generation Sequencing (NGS) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole blood (EDTA or ACD tube), buccal swab, dried blood spot (FTA card), or extracted DNA |
| Methodology Used | Next-Generation Sequencing (NGS) – full gene coverage including splice sites |
| ICD-10-CM Code | G31.82 (Leigh syndrome) |
| LOINC Code | 81247-9 (NDUFS8 gene mutation analysis in Blood or Tissue by Sequencing) |
| DHA Facility License & Laboratory Address | DHA License Number: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians