Test Price
2,800 AED✅ Home Collection Available
MTPAP Gene Spastic Ataxia Type 4 (Autosomal Recessive) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Guaranteed accuracy: 99.9% diagnostic sensitivity using ISO 9001:2015 certified processing (Cert: INT/EGQ/2509DA/3139).
- VIP logistics: hospital-grade home sample collection via ISO-certified cold chain and mobile phlebotomy (daily 8 AM – 11 PM).
- Clinical guidance: post-test teleconsultation with a certified genetic counsellor included.
- Insurance: direct pre-authorization via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This comprehensive genetic test uses Next‑Generation Sequencing (NGS) to detect all pathogenic variants in the coding region and splice sites of the MTPAP gene, responsible for autosomal recessive spastic ataxia type 4 (SPAX4). Our platform delivers definitive diagnostic and carrier information for affected families.
| Feature | Our MTPAP NGS Test | Closest Alternative (Sanger or Panel) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity for all coding variants, including deep intronic mutations (Illumina platform + Sanger confirmation) | ~95% misses large deletions, copy-number variations, or novel non‑coding mutations |
| Methodology | Next‑Generation Sequencing (NGS) with full gene coverage and variant‐by‐variant validation | Targeted single‑gene Sanger sequencing or limited exome panel |
| Turnaround | 3–4 weeks with pre‑test genetic counselling included | 4–6 weeks; often requires separate downstream confirmation |
Physician Insight & Safety Protocols
"As a consultant medical genetics specialist, I understand the profound implications of hereditary ataxia testing. The MTPAP gene result is a key piece of the diagnostic puzzle, yet it must always be correlated with a thorough neurological examination and comprehensive family history. Please discuss the findings with your treating physician before making any health or family‑planning decisions."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Important Safety Advisory
Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals who have received an allogeneic bone marrow transplant within the last 6 months; samples with insufficient or degraded DNA.
- ER Red Flag: Sudden, severe worsening of gait instability, acute vision loss, or new‑onset generalised weakness – seek immediate medical attention as these may signal acute neuro‑ophthalmological deterioration unrelated to the test itself.
Patient FAQ & Clinical Guidance
1. What does the MTPAP gene test detect, and why is it important for spastic ataxia?
This genetic test identifies pathogenic variants in the MTPAP gene causing autosomal recessive spastic ataxia type 4, enabling accurate diagnosis and family planning. The result helps differentiate SPAX4 from other ataxias, guides prognosis, and informs carrier testing for at‑risk relatives.
2. How is the sample collected, and is home collection available in the UAE?
A simple blood draw can be collected by our DHA‑licensed phlebotomist at your home or office between 8 AM and 11 PM daily. Our ISO‑certified cold‑chain logistics preserve sample integrity from collection to lab. For archival tissue specimens, secure medical courier retrieval is used.
3. How long do results take, and who will explain them to me?
Results are reported within 3–4 weeks; a post‑test teleconsult with a certified genetic counsellor is provided to interpret findings and discuss next steps. Your referring neurologist will also receive a comprehensive medical report for urgent clinical correlation.
UAE Regulatory & Data Privacy Adherence
This service complies with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring confidentiality of genetic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing digital health data.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – safeguarding patient safety and consent.
All laboratory processes are ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). For insurance pre‑authorization, send your Emirates ID to WhatsApp +971 54 548 8731.
Clinical & Logistical Metadata
| Test Name | MTPAP Gene Spastic Ataxia Type 4 (Autosomal Recessive) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA tube); VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily 8 AM – 11 PM |
| Methodology Used | Next‑Generation Sequencing (NGS) with Sanger confirmation of all variants |
| ICD-10-CM Code | G11.9 |
| LOINC Code | 21636-8 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians