Test Price
2,800 AED✅ Home Collection Available
FLNA Gene (Periventricular Nodular Heterotopia, X‑Linked Dominant) Genetic Test in UAE 2,800 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing. Premium Logistics: Hospital‑grade home collection with ISO‑certified cold‑chain transport ensures sample integrity from 8 AM to 11 PM. Clinical Guidance: Complimentary telephonic post‑test interpretation with a genetically trained clinician. Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The FLNA gene encodes filamin A, essential for neuronal migration. Pathogenic variants cause periventricular nodular heterotopia (PVNH), an X‑linked dominant disorder leading to drug‑resistant epilepsy and cognitive impairment. This NGS‑based genetic test reads the entire coding sequence to detect single‑nucleotide variants, small indels, and copy‑number changes – the gold‑standard for definitive diagnosis and family risk stratification.
| Feature | Our NGS Test | MLPA + Sanger (Alternative) |
|---|---|---|
| Coverage | Full gene sequencing + CNV detection | Limited to deletions/duplications + selected exons |
| Sensitivity | >99% for all variant types | ~85% (misses deep intronic/missense variants) |
| Turnaround | 3–4 weeks | 4–6 weeks (combined) |
Physician Insight & Safety Protocols
“A positive FLNA result confirms the genetic basis of periventricular nodular heterotopia, guiding tailored antiepileptic therapy and family counselling. However, a negative result does not rule out mosaic or deep intronic variants. I strongly recommend that all patients and families discuss the implications with a consultant medical geneticist and a neurologist before making decisions.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue or adjust any prescribed antiepileptic, antipsychotic, or cardiovascular medication without consulting your treating physician. Genetic test results guide long‑term management but do not replace urgent clinical care.
Exclusion Criteria & Emergency Red Flags
- Inability to provide valid informed consent (patient or legal guardian).
- Active febrile illness or severe coagulation disorder contraindicating blood draw.
- Acute neurological deterioration, status epilepticus, or signs of raised intracranial pressure – seek immediate emergency care before scheduling this test.
- Severe psychiatric condition impairing the understanding of genetic results.
Red Flag: If your child develops sudden visual loss, intractable headache, or prolonged seizure, go to the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What does a positive FLNA gene test mean for my child’s epilepsy treatment?
Snippet Answer: A confirmed pathogenic FLNA variant confirms periventricular nodular heterotopia, allowing your neurologist to tailor antiepileptic drug selection because malformations of cortical development often respond better to specific regimens.
2. How can I prepare for the home blood collection service in Dubai?
Snippet Answer: No fasting is required; simply keep yourself hydrated and have your Emirates ID ready, while our ISO‑certified phlebotomist collects a small blood sample or a finger‑prick drop onto an FTA card.
3. Is the test covered by UAE health insurance for family screening?
Snippet Answer: Coverage depends on your plan; most insurers reimburse when prescribed by a DHA‑licensed neurologist with documented clinical suspicion of PVNH or for cascade testing of first‑degree relatives of a known patient.
UAE Regulatory & Data Privacy Adherence
UAE Legal Compliance: This genetic test is performed in accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability. All samples are processed at DNA Labs UAE (DHA Facility License No. 1143) under ISO 9001:2015 certification. Results are encrypted end‑to‑end and released only to the ordering physician or legal guardian.
Clinical & Logistical Metadata
| Test Name | FLNA Gene (Periventricular Nodular Heterotopia, X‑Linked Dominant) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (venous or finger-prick FTA card) |
| Methodology Used | Next‑Generation Sequencing (NGS) with CNV detection |
| ICD‑10‑CM Code | Q04.8 |
| LOINC Code | 92632-0 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians