Test Price
2,800 AEDโ Home Collection Available
CASK Gene (FG Syndrome Type 4) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary
DNA Labs UAE delivers the CASK gene Next-Generation Sequencing (NGS) test with 99.9% diagnostic sensitivity for FG syndrome type 4, an X-linked neurodevelopmental disorder. The full service package includes VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM, plus post-test telephonic clinical guidance from Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA 9294403). Direct billing verification and insurance pre-authorization are available via WhatsApp at +971 54 548 8731.
- VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM โ 11 PM)
- 99.9% Diagnostic Sensitivity via NGS
- Post-Test Telephonic Clinical Guidance by Consultant Medical Genetics
- WhatsApp Insurance Billing: +971 54 548 8731
Test Overview & Methodology
The CASK gene test employs Next-Generation Sequencing (NGS) to examine the entire coding region of the CASK gene, diagnosing FG syndrome type 4 โ an X-linked neurodevelopmental disorder marked by intellectual disability, hypotonia, and characteristic craniofacial features. NGS provides comprehensive coverage of all exons and splice sites, enabling detection of missense, nonsense, frameshift, and splice-site variants with high confidence.
| Feature | Our Test (NGS) | Alternative (Sanger Sequencing) |
|---|---|---|
| Sensitivity | 99.9% | ~95% |
| Method | NGS (Next Generation Sequencing) | Sanger Sequencing |
| Turnaround | 3โ4 Weeks | 4โ6 Weeks |
Physician Insight & Safety Protocols
โA CASK mutation result must always be interpreted within the full context of the patientโs clinical phenotype, developmental history, and family pedigree. This NGS assay is a powerful diagnostic adjunct, but therapeutic and management decisions require integration with expert clinical genetics evaluation and multidisciplinary assessment.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Guidance for Patients and Clinicians
Patients should continue all prescribed medications and therapies unless explicitly directed otherwise by their treating physician. The genetic result alone should not prompt changes to existing treatment regimens without a formal consultation with a clinical geneticist or neurologist.
Safety Exclusion Criteria & Emergency Red Flags
- Not indicated for acute neurological emergencies; if the patient experiences sudden worsening of symptoms, new-onset seizures, or loss of consciousness, call 998 immediately.
- Exclusion: active bleeding disorder, recent blood transfusion within the last 2 weeks, or inability to provide informed consent.
- All blood sample collections are performed by licensed phlebotomists; report any adverse reaction to the collection team without delay.
- Final results must be interpreted by a neurologist or clinical geneticist in conjunction with the complete clinical picture.
Patient FAQ & Clinical Guidance
1. What is the CASK gene NGS test used for?
This test detects disease-causing mutations across the full coding sequence of the CASK gene to confirm a diagnosis of FG syndrome type 4, an X-linked neurodevelopmental condition. It helps differentiate this syndrome from other genetic causes of intellectual disability and hypotonia, guiding accurate prognosis and family counseling.
2. How accurate is the test and what sample is needed?
Our NGS assay delivers 99.9% diagnostic sensitivity using a standard peripheral blood sample collected via venipuncture. The test requires 3โ5 mL of whole blood in an EDTA tube. Results are typically available within 3โ4 weeks from sample receipt at the laboratory.
3. Is pre-test genetic counseling required before this test?
Yes, our service includes a mandatory pre-test genetic counseling session. The consultant medical geneticist will construct a three-generation family pedigree, review the patientโs medical history, and ensure informed consent is obtained before sample collection proceeds.
4. How do I prepare for the blood sample collection at home?
No special preparation such as fasting is required. Stay well hydrated before the appointment. A licensed phlebotomist will visit your residence between 8 AM and 11 PM. Please inform the team of any bleeding disorders, anticoagulant use, or previous fainting episodes related to blood draws.
5. Can insurance cover the cost of the CASK genetic test?
Many UAE health insurance plans provide partial or full coverage for genetic testing when ordered by a specialist. Our billing team can verify your insurance eligibility and process pre-authorization requests via WhatsApp at +971 54 548 8731. The out-of-pocket price is 2800 AED.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and adheres strictly to the data protection and health information security frameworks established in the UAE. All patient genetic data is processed and stored in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | CASK Gene (FG Syndrome Type 4) Sequencing โ NGS |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full Coding Region & Splice Sites |
| ICD-10-CM Code | Q87.8 |
| LOINC Code | 90268-4 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians