Test Price
2,800 AEDโ Home Collection Available
AP4E1 Gene SPG51 Genetic Test in UAE | 2800 AED | DHA-Approved Next-Generation Sequencing
Executive Summary & Core Metrics
Comprehensive NGS-based analysis for AP4E1 gene-related hereditary spastic paraplegia (SPG51) with 99.9% diagnostic sensitivity.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The AP4E1 Gene SPG51 Genetic Test screens for pathogenic variants in the AP4E1 gene, pinpointing hereditary spastic paraplegia type 51 (SPG51) with industry-leading next-generation sequencing. Our UAE lab delivers comprehensive variant classification and clinical-grade reports within 3โ4 weeks.
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Methodology | Next Generation Sequencing (NGS) | Single-gene Sanger sequencing |
| Diagnostic Precision | 99.9% Sensitivity | ~95% (targets limited regions) |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks |
| Gene Coverage | Full exon & splice-site analysis | Selected exons only |
| UAE DHA Compliance | Fully compliant, DHA-approved | Varies by provider |
Physician Insight & Safety Protocols
โAs a Consultant Medical Genetics, I understand that genetic testing for hereditary spastic paraplegia can be emotionally challenging. This test offers crucial insights into your childโs condition, but results must be interpreted in the context of your full clinical picture. Please remember, a genetic diagnosis does not define your or your familyโs futureโit empowers personalized care.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA: 9294403
Advisory โ Medication Continuity
โ ๏ธ Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Patients unwilling/unable to give informed consent, recent bone marrow transplant (< 6 months), unconfirmed neurological phenotype.
- Emergency Red Flags: Instant loss of motor function, severe respiratory distress, acute neurological decline โ seek emergency care immediately.
Patient FAQ & Clinical Guidance
1. What is the AP4E1 SPG51 test and why is it recommended?
The AP4E1 gene test uses next-generation sequencing to detect mutations causing hereditary spastic paraplegia type 51, a rare neurological movement disorder affecting lower limb stiffness and weakness.
2. How long does it take to receive results and what is the accuracy?
Results are delivered in 3 to 4 weeks with 99.9% diagnostic sensitivity, ensuring highly reliable variant detection and clinical reporting that meets UAE DHA standards.
3. Is home sample collection available and how do I pay via insurance?
Yes, we provide hospital-grade home collection with cold-chain logistics from 8 AM to 11 PM, and direct insurance billing can be verified instantly via WhatsApp at +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection
All services comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Laboratory certified to ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | AP4E1 Gene SPG51 Genetic Test (Next-Generation Sequencing) |
| Price (AED) | 2800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or Saliva |
| Methodology Used | Next-Generation Sequencing (NGS) โ Whole Exome Sequencing with CNV analysis |
| ICD-10-CM Code | G11.4 (Hereditary spastic paraplegia) |
| LOINC Code | 94486-1 (Hereditary spastic paraplegia gene panel) |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians