Test Price
2,800 AED✅ Home Collection Available
NDUFS7 Gene (Leigh Syndrome) Genetic Testing via NGS in UAE – 2800 AED
Executive Summary & Core Metrics
This advanced genetic test for the NDUFS7 gene associated with Leigh syndrome offers 99.9% diagnostic accuracy via Next-Generation Sequencing (NGS) in a DHA-licensed facility. The service includes VIP mobile phlebotomy with temperature-controlled cold-chain home collection, post-test telephonic clinical guidance by a DHA-licensed genetic counsellor, and direct insurance verification via WhatsApp at +971545488731. Testing is performed in an ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) certified laboratory licensed by the Ministry of Health.
ISO 9001:2015 certified NGS processing for unparalleled accuracy.
VIP mobile phlebotomy & hospital-grade cold-chain logistics (8 AM – 11 PM).
Telephonic interpretation by a DHA-licensed genetic counsellor.
WhatsApp verification at +971 54 548 8731 before booking.
Test Overview & Methodology
This targeted Next-Generation Sequencing test analyses the NDUFS7 gene, a critical nuclear-encoded mitochondrial protein associated with Leigh syndrome, a severe paediatric neurometabolic disorder. Early molecular confirmation empowers families with precise diagnosis, carrier identification, and informed reproductive planning.
| Feature | Our Test (NDUFS7 NGS) | Closest Alternative (Whole Exome Sequencing) |
|---|---|---|
| Precision | Targeted deep coverage of coding + splice regions of NDUFS7 | Broad coverage but may miss deep intronic or copy-number variants without specific target |
| Methodology | NGS with Sanger validation of pathogenic variants | Whole Exome Sequencing; incidental findings risk |
| Turnaround | 21–28 Days | 6–8 Weeks |
Physician Insight & Safety Protocols
“Molecular diagnosis of Leigh syndrome requires careful clinical correlation. A positive NDUFS7 variant should be interpreted within the patient’s full metabolic and neurological phenotype. Do not alter treatment without specialist consultation—this test informs, not replaces, clinical judgment.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA License: 9294403.
⚠️ Medication Advisory
Do not discontinue any prescribed medication, especially anti-epileptics or mitochondrial cocktail supplements, without consulting your managing physician. Abrupt changes can precipitate metabolic crisis.
🚨 Patient Safety & Exclusion Criteria
- Active febrile illness or decompensated metabolic episode – postpone collection.
- Patient on blood thinners (e.g., Warfarin) – requires physician clearance for venipuncture.
- For minors, valid guardian consent as per Federal Decree-Law No. 4 of 2016 on Medical Liability; child must not be under 5 kg without neonatologist approval.
- ER Red Flags: If the patient develops acute encephalopathy, seizures, or respiratory distress after sample collection, seek emergency medical attention immediately; these are unrelated to the blood draw but may signal disease progression.
Patient FAQ & Clinical Guidance
1. What does the NDUFS7 genetic test detect, and how does it work?
This test identifies pathogenic variants in the NDUFS7 gene that cause Leigh syndrome, a severe childhood mitochondrial disorder, by using next-generation sequencing to read every coding nucleotide with >99.9% analytic accuracy. The process requires a simple blood sample (or DNA) and compares your sequence against a curated clinical database. Results help confirm diagnosis, assess carrier status, or guide reproductive options.
2. How should I prepare for the test, and is genetic counselling mandatory?
A pre-genetic counselling session is obligatory under Federal Decree-Law No. 4 of 2016 on Medical Liability and Federal Law No. 2 of 2019 to document a detailed family pedigree and explain possible outcomes, ensuring fully informed consent before any sample collection. No fasting is required. Bring previous medical reports and a list of current medications. We offer home-based counselling via secure video call.
3. How is the report delivered and shared with my physician?
The certified genetic report is delivered within 21–28 days via an encrypted online portal, allowing direct sharing with your specialist physician in compliance with UAE Personal Data Protection Law (PDPL). The price of 2800 AED includes sterile home collection. We provide a bilingual English-Arabic report with actionable clinical interpretations.
UAE Regulatory & Data Privacy Adherence
This test is conducted under the strict regulatory framework of the Dubai Health Authority (DHA) and complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient genetic data is encrypted, stored securely, and never shared without explicit consent. Our facility holds DHA License No. 1143 and is located at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | NDUFS7 Gene (Leigh Syndrome) Genetic Testing via NGS |
| Price (AED) | 2,800 AED |
| Turnaround Time | 21–28 Days |
| Sample Type / Matrix | Whole blood (peripheral venous) or extracted DNA |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger validation |
| ICD-10-CM Code | G31.82 |
| LOINC Code | 81269-8 |
| DHA Facility License & Laboratory Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | License: 1143 |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians