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Test Price

2,800 AED

✅ Home Collection Available

EGR2 Gene CMT4E Next‑Generation Sequencing Genetic Test in UAE | 2800 AED

Executive Summary & Core Metrics

  • 99.9% Diagnostic Sensitivity via ISO‑certified processing and full‑gene Next‑Generation Sequencing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM.
  • Clinical Guidance: Telephonic post‑test consultation for result interpretation included.
  • Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The EGR2 gene CMT4E NGS test decodes the entire coding sequence of the EGR2 gene to identify pathogenic variants causing Charcot‑Marie‑Tooth disease type 4E, a severe early‑onset demyelinating neuropathy. The test uses Next‑Generation Sequencing (NGS) to confirm the molecular diagnosis and guide genetic counselling and treatment planning with certified accuracy.

Feature Our Test (NGS) Closest Alternative (Sanger Sequencing)
PrecisionFull‑gene coverage, >99% sensitivity for point mutations & small indelsLimited to selected exons; risk of missing deep intronic or novel variants
MethodologyNext‑Generation Sequencing (NGS) with confirmatory Sanger validationSanger sequencing of individual amplicons
Turnaround Time3–4 Weeks4–6 Weeks
Clinical UtilityComprehensive genotype–phenotype correlation, carrier testing & family screeningBasic mutation detection, less informative for complex rearrangements

Physician Insight & Safety Protocols

“A diagnosis of Charcot‑Marie‑Tooth disease can be deeply unsettling for patients and families. This test confirms the molecular basis of CMT4E, allowing us to tailor rehabilitation strategies and discuss inheritance risks with empathy. Please remember that genetic results must be integrated with a complete neurological exam—never self‑interpret.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Do Not Discontinue Prescribed Medication

🔴 Do not discontinue or alter any prescribed medication without consulting your physician. Genetic test results are adjunctive and do not replace ongoing clinical management.

Exclusion Criteria & Emergency Red Flags

  • Acute febrile illness or active systemic infection – reschedule post recovery.
  • Recent blood transfusion or bone marrow transplant (within 4 weeks) – invalidates DNA source.
  • Co‑existing severe respiratory or cardiac compromise – immediate physician assessment required.
  • Seek emergency care if: sudden worsening of limb weakness, swallowing difficulty, or respiratory distress develops before or after testing.

Patient FAQ & Clinical Guidance

1. How is the EGR2 gene test used to diagnose Charcot‑Marie‑Tooth disease?

This Next‑Generation Sequencing test reads the entire EGR2 gene to identify disease‑causing mutations responsible for Charcot‑Marie‑Tooth type 4E, providing molecular confirmation of the clinical diagnosis.

2. Do I need to fast before sample collection?

No fasting is required. A simple blood draw, extracted DNA, or one drop of blood on an FTA card is sufficient for the test.

3. How long do results take and does the price include genetic counselling?

Results are reported within 3–4 weeks and the package includes a post‑test genetic counselling session to explain your personal results.

UAE Regulatory & Data Privacy Adherence

This test is performed in strict compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability. All genetic data is encrypted, anonymised, and processed within secure UAE‑based servers.

Clinical & Logistical Metadata

Test Name EGR2 Gene CMT4E Next‑Generation Sequencing
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Peripheral whole blood, extracted DNA, or FTA card
Methodology Used Next‑Generation Sequencing (NGS) with confirmatory Sanger validation
ICD‑10‑CM Code G60.0
LOINC Code 94409-2
DHA Facility License & Laboratory Address License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE

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