Test Price
2,800 AED✅ Home Collection Available
ANO3 Gene (DYT24) Genetic Test in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity through ISO 9001:2015 Accredited NGS Processing
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) across all UAE cities.
Clinical Guidance: Telephonic Post-Test Genetic Counseling by DHA-licensed Consultant Medical Geneticist.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 (response within 15 minutes).
Pricing: 2,800 AED – includes full gene sequencing, bioinformatic analysis, and comprehensive clinical report.
Test Overview & Methodology
The ANO3 gene (DYT24) Next Generation Sequencing (NGS) test analyzes the entire coding region and splice sites of the ANO3 gene to detect pathogenic variants associated with autosomal dominant dystonia type 24. This test is indicated for individuals with early-onset cervical or laryngeal dystonia, a family history of dystonia, or unexplained movement disorders. Results provide definitive genetic confirmation, enabling targeted neurological management and family cascade screening.
The assay employs Illumina® NGS technology with orthogonal confirmation of clinically significant variants via Sanger sequencing. All interpretations follow ACMG/AMP guidelines and are independently reviewed by a clinical molecular geneticist.
| Feature | Our ANO3 NGS Test | Single-Gene Sanger (Alternative) |
|---|---|---|
| Analytical Sensitivity | 99.9% – detects all exonic variants, splice-site variants, and small indels | ~95% – limited to known hotspot mutations |
| Methodology | Illumina NGS with orthogonal Sanger confirmation and CNV analysis | Capillary electrophoresis; no copy number detection |
| Turnaround Time | 3–4 weeks (expedited 2-week option available) | 6–8 weeks |
| Sample Types | Whole blood (2–5 mL EDTA), extracted DNA (≥1 µg), or FTA card (3 dried blood spots) | Whole blood only (2–5 mL) |
| Price (UAE) | 2,800 AED | 2,100–2,500 AED |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist licensed by the DHA, I emphasize that a positive ANO3 variant confirmation should always be correlated with the full clinical phenotype, family history, and segregation analysis. A negative result does not exclude other dystonia-associated genes. Pre- and post-test genetic counseling is essential for emotional preparedness and informed decision-making, especially for at-risk relatives.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory – Medication & Clinical Management
Genetic results complement but do not replace clinical judgment. Do not discontinue any prescribed anti-dystonia medications (e.g., trihexyphenidyl, baclofen, botulinum toxin) without consulting your treating neurologist. A positive genetic finding may inform treatment choice but does not predict symptom severity or progression.
Exclusion Criteria & Safety Red Flags
- Inability or unwillingness to provide informed consent (for minors, consent from a legally authorized representative is mandatory).
- Absence of documented pre-test genetic counseling session with pedigree analysis.
- Acute psychiatric instability that may impair comprehension of probabilistic genetic results.
- Inadequate or degraded DNA sample (e.g., insufficient blood volume, hemolysis, or improperly spotted FTA card).
If you experience sudden worsening of muscle spasms, respiratory difficulty, or swallowing impairment, seek emergency care immediately – do not wait for test results.
Patient FAQ & Clinical Guidance
1. What is the turnaround time for the ANO3 NGS test in Dubai?
Standard reporting time is 3 to 4 weeks from sample receipt. An expedited option (2 weeks) is available for urgent neurological consultations upon request.
2. Can home collection be arranged for this genetic test in Abu Dhabi and Sharjah?
Yes. Our DHA-licensed VIP Mobile Phlebotomy team provides temperature-controlled home collection across all UAE emirates, including Abu Dhabi and Sharjah, daily from 8 AM to 11 PM. The sample is transported under cold-chain integrity to our laboratory.
3. What actions should I take if my ANO3 test result is positive?
A positive result should be reviewed with your neurologist and a genetic counselor. They will assess clinical implications, recommend family cascade testing for at-risk relatives, and discuss personalized treatment options including medication adjustments or deep brain stimulation candidacy.
4. Does insurance cover the ANO3 genetic test?
Coverage varies by insurance provider. We offer direct billing verification via WhatsApp at +971 54 548 8731 – typically responded to within 15 minutes. Prior approval may be required; our team can assist with documentation.
UAE Regulatory & Data Privacy Adherence
This test complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is stored and processed within UAE sovereign servers under strict confidentiality. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139).
For appointments, sample collection scheduling, and insurance verification, contact us via WhatsApp: +971 54 548 8731.
Clinical & Logistical Metadata
| Test Name | ANO3 Gene (DYT24) Next Generation Sequencing (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks (expedited 2-week option) |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card (dried blood spots) |
| Methodology Used | Next Generation Sequencing (Illumina®) with orthogonal Sanger confirmation and CNV analysis |
| ICD-10-CM Code | G24.1 (Genetic dystonia) |
| LOINC Code | 102022-8 (ANO3 gene sequencing) |
| DHA Facility License & Laboratory Address | DHA License: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians