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Test Price

2,800 AED

✅ Home Collection Available

NLGN3 Gene Asperger Syndrome Susceptibility X-Linked Type 2 Genetic Test in UAE | 2800 AED

Executive Summary & Core Metrics

  • Diagnostic Sensitivity 99.9% – 99.9% Analytical Sensitivity & Specificity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
  • VIP Mobile Phlebotomy & Cold-Chain Transport – Hospital-grade home collection available daily from 8 AM to 11 PM across all emirates.
  • Post-Test Genetic Counseling – Telephonic guidance by a DHA-licensed Consultant Medical Geneticist in result interpretation.
  • Direct Insurance Billing – Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The NLGN3 gene test employs Next-Generation Sequencing (NGS) to analyze the entire coding region and flanking intronic boundaries of the NLGN3 gene, identifying pathogenic variants linked to X-linked Asperger syndrome susceptibility. This advanced genomic screening enables early risk stratification for autism spectrum disorders and is offered exclusively as an elective, non-emergency test following genetic counseling.

Feature Our Genetic Test Closest Alternative (Single‑Gene Sanger Sequencing)
Precision 99.9% Analytical Sensitivity & Specificity ~99.0%, may miss low‑level mosaicism
Method NGS (Illumina NovaSeq) – full gene + intron‑exon boundaries Capillary electrophoresis, limited to targeted exons
Turnaround 3–4 Weeks 4–6 Weeks
Variant Detection SNVs, indels, CNVs across NLGN3 Only pre‑defined point mutations

Physician Insight & Safety Protocols

“The NLGN3 genetic result must be interpreted alongside a comprehensive neurodevelopmental assessment and detailed family history; a single variant does not establish a clinical diagnosis of Asperger syndrome. Any finding indicating elevated susceptibility should prompt integrated multidisciplinary care, never abrupt discontinuation of existing therapies. This test is a guide for early intervention, not a standalone verdict.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics
DHA Registration ID: 9294403

⚠ Medication Advisory

Do not stop prescribed medications or behavioral therapies without consulting your clinician. Genetic information may influence future management but does not replace current treatment plans.

Safety Exclusion Criteria & Emergency Red Flags

  • Patients with a known bleeding disorder or severe anemia require medical clearance before phlebotomy.
  • This test is elective genomic screening; it is not intended for acute diagnostic emergencies.
  • If the patient exhibits acute suicidal ideation, severe aggression, or catatonia, seek immediate psychiatric emergency care (call 998 in UAE).
  • Home collection is postponed if the patient has a fever >38.5°C or active infection.

Patient FAQ & Clinical Guidance

1. What is the NLGN3 gene test and who should consider it?

This NGS test identifies pathogenic variants in the NLGN3 gene associated with X-linked Asperger syndrome susceptibility, aiding early risk stratification for autism spectrum disorders. It is typically ordered for individuals with a family history of Asperger syndrome or unexplained social-communication delays, after genetic counseling.

2. How is the sample collected and what is the turnaround time?

A certified phlebotomist collects 2–4 mL of whole blood in an EDTA tube. A dry blood spot on a DNA FTA card is also acceptable. Results are ready in 3–4 weeks. VIP mobile phlebotomy is available daily from 8 AM to 11 PM across all emirates.

3. Is the test approved by UAE health authorities and covered by insurance?

The test is fully compliant with the DHA regulatory framework and is performed at an ISO 9001:2015 accredited laboratory. Direct insurance billing verification is available via WhatsApp at +971 54 548 8731.

UAE Regulatory & Data Privacy Adherence

Data Privacy & Health Information Protection: This test is conducted in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-controlled, and processed solely for diagnostic purposes. Patient consent is obtained per Federal Decree-Law No. 4 of 2016 on Medical Liability. Results are shared only with the ordering physician and the patient through secure channels.

Clinical & Logistical Metadata

Test Name NLGN3 Gene Asperger Syndrome Susceptibility X-Linked Type 2 Genetic Test
Price (AED) 2,800
Turnaround Time 3–4 Weeks
Sample Type / Matrix Peripheral Whole Blood (EDTA) or Dry Blood Spot (FTA Card)
Methodology Used Next-Generation Sequencing (NGS) – Illumina NovaSeq
ICD-10-CM Code Z15.89
LOINC Code 92872-6
DHA Facility License & Laboratory Address DHA License No: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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