Test Price
2,800 AED✅ Home Collection Available
MPZ Gene Dejerine‑Sottas Disease Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Laboratory Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Genetic Counselling by a DHA‑Licensed Specialist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The MPZ Gene NGS Test comprehensively sequences the entire coding region of the myelin protein zero gene to diagnose Dejerine‑Sottas disease and related hereditary neuropathies. This test identifies pathogenic variants responsible for CMT1B, Dejerine‑Sottas syndrome, and congenital hypomyelination, guiding precise clinical management and family planning.
| Feature | Our Test (NGS Full Gene) | Closest Alternative (Single‑Site Panel) |
|---|---|---|
| Precision | 99.9% analytic sensitivity for all MPZ variants | Limited to known hot‑spots; may miss novel mutations |
| Methodology | Next Generation Sequencing (NGS) with copy number analysis | Targeted Sanger sequencing of selected exons |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
Physician Insight & Safety Protocols
As a Consultant Medical Genetics with a focus on hereditary neuropathies, I emphasize that the MPZ genetic test provides definitive molecular confirmation when clinical suspicion is high. However, results must be correlated with a complete neurological evaluation and family history. This test is a powerful tool for personalized management and reproductive planning.
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue any prescribed medication without consulting your physician. Genetic testing does not replace ongoing neurological management. Always follow your treating doctor's guidance regarding medications.
Safety & Exclusion Criteria
- This test is not a stand‑alone diagnostic tool; clinical correlation by a neurologist or geneticist is mandatory.
- Testing is intended for individuals with clinical signs of hereditary neuropathy or a significant family history; asymptomatic screening should follow genetic‑counselling review.
- Minors may only be tested with verified parental consent and mandatory pre‑test genetic counselling as mandated by UAE medical regulations.
- Emergency Red Flags: Seek immediate medical care if you experience sudden, rapid worsening of muscle weakness, difficulty breathing, or loss of independent walking — these signs relate to the underlying disease, not the test procedure.
Patient FAQ & Clinical Guidance
1. What does the MPZ genetic test detect?
Identifies MPZ gene variants causing CMT1B, Dejerine‑Sottas disease, and congenital hypomyelination with 99.9% diagnostic sensitivity. This NGS‑based assay examines the full coding sequence and copy number variations in the MPZ gene, which encodes the myelin protein zero critical for peripheral nerve insulation. Pathogenic mutations are responsible for the majority of Dejerine‑Sottas neuropathy cases and a subset of Charcot‑Marie‑Tooth type 1B; early molecular confirmation supports accurate prognosis, treatment selection, and family risk assessment.
2. How is the sample collected?
Your blood or FTA card sample is collected comfortably at home by a DHA‑licensed phlebotomist. After scheduling, a trained specialist arrives with full cold‑chain equipment. A single venipuncture or a blood spot on an FTA card is obtained; the painless collection takes less than five minutes. The specimen is immediately secured and transported under ISO 9001:2015 cold‑chain conditions to our laboratory, where DNA is extracted for NGS analysis.
3. What is the turnaround time and cost?
Results are delivered within 3 to 4 weeks at a total cost of 2800 AED. This inclusive timeframe covers sequencing, bioinformatic interpretation by a clinical geneticist, and generation of a comprehensive report. The final report will be shared through our secure online portal, and a telephonic genetic counselling session is offered at no extra charge to explain the findings and next steps.
UAE Regulatory & Data Privacy Adherence
Your data is protected. DNA Labs UAE complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic information is encrypted, access‑restricted, and processed solely for diagnostic purposes with your explicit consent. We adhere to strict confidentiality protocols and never share data without legal authorization.
Clinical & Logistical Metadata
| Test Name | MPZ Gene Dejerine‑Sottas Disease Genetic Test |
| Price (AED) | 2800 |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Whole Blood (peripheral) or FTA Card Blood Spot – VIP Mobile Phlebotomy Home Collection Available (8 AM – 11 PM) |
| Methodology Used | Next Generation Sequencing (NGS) with copy number variation analysis |
| ICD-10-CM Code | G60.0 |
| LOINC Code | 48018-5 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – Corporate Lab: DNA Labs UAE |
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