Test Price
2,800 AEDโ Home Collection Available
GNB4 Gene CMTDIF Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity โ ISO 9001:2015 certified sequencing (Cert: INT/EGQ/2509DA/3139)
- Premium Logistics โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM)
- Clinical Guidance โ Complimentary telephonic post-test result interpretation by DHA-licensed Consultant Medical Genetics Lina Osama Zaki Quteineh (DHA ID: 9294403)
- Insurance โ Direct billing verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
This Next-Generation Sequencing (NGS) test examines the full coding region of the GNB4 gene to detect pathogenic variants causing Charcot-Marie-Tooth disease, dominant intermediate type F (CMTDIF). It is the definitive diagnostic tool for hereditary motor and sensory neuropathy with a 3โ4 week turnaround.
| Parameter | Our NGS Test | Sanger Sequencing (Alternative) |
|---|---|---|
| Precision | 99.9% single-nucleotide variant detection | ~95% (misses deep intronic/mosaic variants) |
| Methodology | NGS (Illumina NovaSeq) with CNV analysis | Capillary sequencing (gene-by-gene) |
| Turnaround Time | 3โ4 weeks | 6โ8 weeks |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics, I understand the profound uncertainty that accompanies genetic testing for hereditary neuropathies. The GNB4 NGS assay offers precise molecular clarity, but results must always be interpreted alongside clinical presentation and family history. Accurate diagnosis is the cornerstone of effective genetic counseling and personalized care."
โ Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Important Safety Advisory
โ Medication Warning
Do not discontinue any prescribed medication without consulting your treating physician. This test does not replace ongoing neurology care, and abrupt cessation of neurotropic drugs can precipitate serious adverse events.
Exclusion Criteria & Red Flags
- Exclusion: Recent blood transfusion (within 4 weeks) or active osteomyelitis โ may cause DNA chimerism.
- Exclusion: Inability to provide informed consent (legal guardian required for minors per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Emergency Red Flag: Sudden onset of severe muscle weakness, respiratory distress, or bulbar symptoms โ proceed to ER immediately; genetic testing is not appropriate in acute settings.
Patient FAQ & Clinical Guidance
1. What is the GNB4 CMTDIF test and how does it help diagnose Charcot-Marie-Tooth disease?
Snippet Answer: This advanced NGS test analyzes the GNB4 gene to diagnose Charcot-Marie-Tooth disease type DIF, a hereditary neuropathy causing progressive muscle weakness.
The assay identifies pathogenic single-nucleotide variants and copy-number changes, confirming a molecular diagnosis that guides targeted physiotherapy, occupational therapy, and genetic counseling for at-risk family members.
2. Why is the test priced at 2800 AED and does insurance cover it?
Snippet Answer: The 2800 AED cost reflects high-depth NGS, bioinformatic interpretation, and DHA-mandated genetic counseling, with direct insurance verification available via WhatsApp.
Our facility submits eligibility for all major UAE insurers; send your policy copy to +971 54 548 8731 for instant confirmation. Coverage is subject to your policy terms and benefits.
3. What sample is needed and how does the home collection work?
Snippet Answer: A simple blood draw, extracted DNA, or a single drop of blood on an FTA card is collected at home by our DHA-licensed team.
The sample is transported in a validated cold-chain system at 2โ8ยฐC to our ISO 9001:2015 facility. Results are delivered in 3โ4 weeks with a telehealth consultation to discuss findings.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly complies with the following UAE federal legal frameworks:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ Ensuring the confidentiality and security of your genetic and personal data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ Governing the safe and ethical use of health data and telemedicine.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ Protecting patient rights and informed consent in clinical and diagnostic procedures.
Accreditation: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | GNB4 Gene Sequencing (CMTDIF) |
| Price (AED) | 2,800 |
| Turnaround Time | 21โ28 Days (3โ4 Weeks) |
| Sample Type / Matrix | Peripheral Whole Blood or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) - Illumina NovaSeq with CNV Analysis |
| ICD-10-CM Code | G60.0 (Hereditary motor and sensory neuropathy) |
| LOINC Code | 81263-6 (GNB4 gene targeted mutation analysis) |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Brand: DNA Labs UAE |
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