Test Price
1,500 AED✅ Home Collection Available
Spinocerebellar Ataxia (SCA) Genetic Profile (4 Markers) Test in UAE | 1,500 AED | DHA Licensed
Executive Summary & Core Metrics
Analytical Sensitivity: 99.9% via PCR Fragment Analysis with ISO 9001:2015 Accredited Processing.
Specimen Collection: VIP Mobile Phlebotomy and Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
Post-Test Support: Telephonic clinical guidance session with a Consultant Medical Genetics Specialist included.
Direct Billing Verification: Available via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The Spinocerebellar Ataxia (SCA) Profile (4 Markers) Test is a molecular genetic assay that screens for pathogenic trinucleotide repeat expansions in four genes commonly associated with autosomal dominant cerebellar ataxia: SCA1, SCA2, SCA3, and SCA6. The test employs polymerase chain reaction (PCR) amplification followed by capillary electrophoresis fragment analysis (GeneScan / STR typing) to precisely determine repeat lengths. Results enable definitive diagnosis of hereditary ataxia, guide prognosis, and inform cascade genetic counselling for at-risk family members.
| Feature | SCA 4-Marker Panel (Our Test) | Single-Gene Sequencing Approach |
|---|---|---|
| Analytical Sensitivity | 99.9% (PCR + Fragment Analysis) | ~95% (Sanger Sequencing of one locus) |
| Methodology | PCR + Capillary Electrophoresis / Fragment Analysis (GeneScan / STR) | PCR + Sanger Sequencing |
| Turnaround Time | Report by Saturday (sample received by Tuesday 11:00 AM) | 7 to 10 business days |
| Covered Markers | SCA1, SCA2, SCA3, SCA6 | One gene per order |
Physician Insight & Safety Protocols
"This 4-marker SCA panel provides high-confidence molecular confirmation of hereditary ataxia when clinical presentation and family history suggest an autosomal dominant inheritance pattern. A negative result does not exclude all forms of ataxia; broader next-generation sequencing panels may be indicated if suspicion remains high. I strongly advise patients to correlate genetic findings with a comprehensive neurological examination and to engage in genetic counselling prior to and after testing."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory & Critical Safety Information
Do not discontinue any prescribed medication without prior consultation with your treating physician.
Pre-Test Requirement:
A duly completed Genomics Clinical Information Requisition Form (Form 20) is mandatory for sample acceptance. Please ensure all sections are filled and signed by the referring clinician.
Exclusion Criteria & Emergency Red Flags
- Severe acute illness or hemodynamic instability – defer collection until clinical stabilisation.
- Recent blood transfusion within the preceding two weeks may interfere with germline DNA analysis.
- Sudden or progressive worsening of gait, vision, speech, or consciousness requires immediate emergency medical evaluation.
Patient FAQ & Clinical Guidance
1. What is the purpose of the SCA 4-marker genetic test?
This test detects disease-causing trinucleotide repeat expansions in the SCA1, SCA2, SCA3, and SCA6 genes. These expansions are responsible for the majority of autosomal dominant cerebellar ataxias. Confirming the genetic subtype allows for precise prognosis, targeted management, and accurate genetic counselling for family members.
2. How should I prepare for the blood draw?
No fasting or special dietary preparation is required. The only prerequisite is a fully completed and signed Genomics Clinical Information Requisition Form (Form 20), which must be handed to the phlebotomist at the time of collection.
3. When will I receive my results and how are they delivered?
If your blood sample is received in the laboratory by Tuesday at 11:00 AM, the final clinical report will be issued on the following Saturday. Results are accessed through a secure online patient portal and are followed by a scheduled telephonic post-test guidance session with a Consultant Medical Genetics specialist.
4. Does a negative result rule out all forms of hereditary ataxia?
No. This panel covers only four of the more than 40 known SCA subtypes. A negative result significantly reduces the likelihood of these common forms but does not exclude ataxias caused by rare or non-repeat-expansion mechanisms. Your genetic counsellor or neurologist may recommend a broader next-generation sequencing panel if clinical suspicion remains high.
UAE Regulatory & Data Privacy Adherence
Data Protection: All genetic data is processed and stored in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent, data minimisation, and secure transmission protocols are enforced throughout the testing lifecycle.
Clinical Safety & Liability: Specimen collection and diagnostic reporting adhere to the standards set forth in Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring patient safety and professional accountability.
ISO Certification: ISO 9001:2015 Certified (Cert. No. INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | Spinocerebellar Ataxia (SCA) Genetic Profile (4 Markers) |
| Price (AED) | 1,500 AED |
| Turnaround Time | Report by Saturday (sample received by Tuesday 11:00 AM) |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) |
| Methodology Used | PCR + Capillary Electrophoresis Fragment Analysis (GeneScan / STR) |
| ICD-10-CM Code | G11.9 (Hereditary ataxia, unspecified) / G11.8 (Other hereditary ataxias) |
| LOINC Code | 94249-3 (Spinocerebellar ataxia 1, 2, 3, 6 repeat expansion panel) |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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