NF1 Gene Neurofibromatosis Type 1 Genetic Test in UAE | 2800 AED

Executive Summary & Core Metrics

Executive Summary

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.

Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).

Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.

Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This state-of-the-art genetic test employs Next Generation Sequencing (NGS) to analyze the entire NF1 gene coding region, detecting single nucleotide variants, small insertions/deletions, and copy number variations that cause neurofibromatosis type 1 (NF1). It is the gold-standard for confirming clinical suspicion, assessing familial risk, and guiding oncology/neurology surveillance plans.

Feature	Our NGS Test (ISO-Certified)	Closest Alternative (Standard Targeted Panel)
Diagnostic Sensitivity	99.9% analytical, full gene coverage	~85% (misses deep intronic/CNVs)
Methodology	NGS with copy number analysis	Sanger sequencing or limited multiplex ligation probe amplification
Turnaround Time	3–4 Weeks	4–8 Weeks
UAE Regulatory Compliance	Full DHA/MOHAP genetic testing standards	May not include pedigree counseling step

Physician Insight & Safety Protocols

“A positive NF1 test result is a piece of a complex clinical puzzle. It does not replace a thorough physical examination by a multidisciplinary team, but it empowers you with knowledge. As your consulting physician, I will guide you through what the variant means for you or your child—whether it’s risk stratification, early intervention, or simply peace of mind. You are not alone in this journey.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Safety Exclusion Criteria & Emergency Red Flags

Exclusion Criteria: Hemolyzed blood samples, clotted specimens, insufficient DNA (<1 µg), or FTA cards with incomplete saturation. Recent allogeneic bone marrow transplant may confound results—please contact the lab before collection.
Emergency Red Flags: If you experience sudden vision loss, new-onset seizures, severe and persistent headache with vomiting, or rapidly enlarging painful soft-tissue masses, seek immediate emergency care, as these may indicate optic pathway gliomas or malignant transformation.

Pre-Test Genetic Counseling

Mandatory Counseling: Under UAE federal regulations, pre-test genetic counseling is mandatory. A detailed pedigree chart is drawn and informed consent obtained. The session is conducted by our consultant medical geneticist.

Patient FAQ & Clinical Guidance

1. What does the NF1 Genetic Test detect, and who should consider it?

This test detects pathogenic variants in the entire NF1 gene using Next Generation Sequencing. It is recommended for individuals with clinical features such as café-au-lait spots, neurofibromas, Lisch nodules, or a family history of neurofibromatosis type 1. Predictive testing for at-risk relatives is also available.

2. How accurate is this test, and what are the turnaround times?

The test achieves 99.9% analytical sensitivity and specificity, surpassing standard panels, with results delivered in 3–4 weeks. Our ISO 9001:2015 certified lab uses validated NGS chemistry and Sanger confirmation of all clinically significant variants to eliminate false positives.

3. What pre-test steps are required, and is genetic counseling mandatory?

Yes, pre-test genetic counseling is mandatory under UAE regulations. You will review your personal and family medical history, and a blood sample (or FTA card) will be collected after informed consent. The session includes pedigree analysis and discussion of possible outcomes.

4. Can the test be performed with a home collection kit?

Yes, for peripheral whole blood samples, we offer VIP Mobile Phlebotomy and Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM. For FTA cards, secure courier retrieval is available.

5. What regulatory standards govern this test in the UAE?

This test is performed under DHA Facility License 1143 and adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of ICT in Health Fields. Patient consent follows Federal Decree-Law No. 4 of 2016 on Medical Liability.

UAE Regulatory & Data Privacy Adherence

Compliance Statement

All genetic testing services at DNA Labs UAE are fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection and Federal Law No. 2 of 2019 for health information security. Informed consent is obtained under the provisions of Federal Decree-Law No. 4 of 2016. Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and operates under DHA Facility License 1143.

Clinical & Logistical Metadata

Test Name	NF1 Gene Neurofibromatosis Type 1 Genetic Test (NGS)
Price (AED)	2,800 AED
Turnaround Time	3–4 Weeks
Sample Type / Matrix	Peripheral whole blood (EDTA) or FTA card
Methodology Used	Next-Generation Sequencing (NGS) with copy number variation analysis
ICD-10-CM Code	Q85.0
LOINC Code	81349-5
DHA Facility License & Laboratory Address	License No. 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE DNA Labs UAE