Test Price
2,800 AED✅ Home Collection Available
MLYCD Gene Malonyl-CoA Decarboxylase Deficiency Genetic Test in UAE | 2,800 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO-certified NGS laboratory processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
Clinical Guidance: Telephonic post-test counselling with a DHA-licensed consultant medical geneticist for comprehensive result interpretation.
Insurance: Direct billing verification via WhatsApp +971 54 548 8731 – reply within 15 minutes.
Test Overview & Methodology
The MLYCD gene test detects pathogenic variants causing malonyl-CoA decarboxylase deficiency, a rare autosomal recessive fatty acid oxidation disorder. Using next-generation sequencing covering all coding exons and splice junctions, this genetic test provides definitive molecular diagnosis for patients with unexplained metabolic crises, hypoglycemia, or cardiomyopathy. Comprehensive bioinformatics analysis identifies single nucleotide variants, small insertions or deletions, and copy number variations with high sensitivity.
| Parameter | Our Test (DNA Labs UAE) | Closest Alternative |
|---|---|---|
| Methodology | NGS with Sanger validation of all identified variants | PCR-based single-gene analysis |
| Turnaround Time | 3–4 weeks | 5–6 weeks |
| Diagnostic Yield | >95% for MLYCD point mutations and CNVs | ~80% (misses deep intronic and regulatory variants) |
| Sample Types | Whole blood, extracted DNA, or FTA card specimen | Whole blood only |
| Price | 2,800 AED | 3,200–4,500 AED |
Physician Insight & Safety Protocols
"MLYCD gene sequencing offers definitive molecular confirmation of malonyl-CoA decarboxylase deficiency, yet results must be integrated with urine organic acid profiling and clinical phenotype. A thorough three-generation family pedigree is essential for accurate variant classification and recurrence risk counseling. This test alone does not predict disease severity and should always be paired with metabolic specialist evaluation."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Important Medication Warning
Do not discontinue prescribed carnitine, riboflavin, or anticonvulsant therapies prior to genetic testing without explicit consultation with your treating physician. Abrupt withdrawal of these medications may precipitate acute metabolic decompensation requiring emergency intervention.
Exclusion Criteria & Emergency Red Flags
- Recent blood transfusion within 2 weeks may introduce donor DNA – reschedule testing after a 4-week interval.
- Severe anemia with hemoglobin below 8 g/dL requires physician clearance before venipuncture.
- Uncontrolled seizure activity or hypoglycemia at the time of collection – stabilize the patient first.
- Red Flag: If after home blood draw you develop a large hematoma, fever, or uncontrolled bleeding, seek emergency medical care immediately.
Patient FAQ & Clinical Guidance
1. What is the MLYCD gene test and how does it confirm malonyl-CoA decarboxylase deficiency?
Direct Answer: This genetic test sequences the entire MLYCD gene to identify pathogenic mutations, confirming malonyl-CoA decarboxylase deficiency with near-absolute diagnostic certainty when correlated with clinical symptoms and biochemical findings.
The test detects single nucleotide variants, small insertions or deletions, and copy number variations across all coding exons and conserved splice regions, making it the most comprehensive non-invasive molecular diagnostic approach available. Pre-test genetic counselling including a three-generation pedigree is recommended to support accurate variant interpretation.
2. How is the sample collected and can the test be performed on infants?
Direct Answer: Sample collection uses a standard venipuncture for whole blood, an FTA card for a single heel-prick or finger-stick drop, or extracted DNA, making it suitable for patients of all ages including newborns.
For infants and children, an FTA card is preferred as it requires minimal blood volume and stabilizes DNA at room temperature for transport. No fasting is required. A licensed nurse can perform the collection at home within 15 minutes. Parental or guardian consent is mandatory for minors under UAE Federal Law. The specimen is sent via temperature-controlled courier to the central laboratory with results available in 3 to 4 weeks.
3. Will my health insurance cover the MLYCD genetic test in the UAE?
Direct Answer: Most UAE health insurers now provide coverage for genetic testing of inborn errors of metabolism when ordered by a DHA-licensed metabolic specialist or clinical geneticist, with pre-authorisation required for the 2,800 AED test fee.
We verify your coverage directly via WhatsApp at +971 54 548 8731; please send your Emirates ID, insurance card, and referral letter. Under UAE PDPL regulations, all genetic data is encrypted and stored in a DHA-compliant health information exchange, and you may request deletion at any time. A mandatory pre-test genetic counselling session is included to draw a family pedigree and obtain informed consent.
UAE Regulatory & Data Privacy Adherence
This diagnostic service operates in full compliance with UAE federal data protection and health information governance frameworks. All genetic data is processed under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE maintains ISO-certified laboratory standards and DHA licensure to ensure the highest levels of data security, patient confidentiality, and diagnostic accuracy.
Clinical & Logistical Metadata
| Test Name | MLYCD Gene Malonyl-CoA Decarboxylase Deficiency Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood, extracted DNA, or FTA card specimen |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger validation |
| ICD-10-CM Code | E71.1 |
| LOINC Code | 93134-2 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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