Test Price
2,800 AEDโ Home Collection Available
ICK Gene Endocrine-Cerebroosteodysplasia Genetic Test
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM โ 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance with a certified clinical geneticist for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The ICK Gene Endocrine-Cerebroosteodysplasia Genetic Test is a definitive next-generation sequencing analysis targeting all coding regions of the ICK gene. This test resolves the molecular etiology of this ultra-rare multi-system disorder characterized by endocrine, neurological, and skeletal dysplasia, enabling personalized therapeutic strategies.
A pre-test genetic counselling session with a certified clinical geneticist is mandatory to draw a detailed family pedigree and obtain informed consent, as required by UAE medical practice standards.
| Feature | Our Test (NGS) | Closest Alternative |
|---|---|---|
| Methodology | Next-Generation Sequencing (100% coding region coverage) | Sanger Sequencing (selected exons only) |
| Precision / Sensitivity | >99.9% for single nucleotide variants and indels | ~95% for targeted mutations |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks |
| Regulatory Compliance | DHA/MOHAP Licensed, ISO 9001:2015, UAE PDPL | Often limited to international reference labs |
Physician Insight & Safety Protocols
Clinical Insight from Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403): "Navigating a rare diagnosis like Endocrine-Cerebroosteodysplasia is emotionally challenging for families. This NGS test provides molecular clarity, but it is essential to interpret results within the full clinical and pedigree context. A negative result does not exclude the diagnosis, and variant classification may evolve with updated databases."
Advisory & Pre-Test Considerations
- Genetic test results require clinical correlation and must not be used as sole basis for treatment decisions.
- Do not discontinue any prescribed medication (e.g., hormone replacement, anti-epileptics) without consulting your treating physician.
- Informed consent must be obtained after thorough pre-test counselling.
Exclusion Criteria & Emergency Red Flags
โ Contraindications & Urgent Signs
Exclusion Criteria
- Recent whole blood transfusion (within 2 weeks).
- Inability to provide informed consent or confirm legal guardianship.
- Grossly hemolyzed or contaminated sample (recollection will be advised).
Emergency Red Flags (Seek Immediate Medical Care if Present)
- Acute adrenal insufficiency (hypotension, shock, hypoglycemia).
- Unexplained seizures or loss of consciousness.
- Pathological fractures without trauma.
- Severe metabolic acidosis or electrolyte imbalance.
This genetic test is a diagnostic aid, not an emergency tool. For acute symptoms, proceed to your nearest ER.
Patient FAQ & Clinical Guidance
1. What does the ICK gene test detect?
In Brief: It detects pathogenic variants in the ICK gene linked to Endocrine-Cerebroosteodysplasia, covering endocrine anomalies, brain malformations, and skeletal dysplasia. This NGS test screens all coding exons and exonโintron boundaries for single nucleotide changes, small insertions/deletions, and copy number variations. A positive finding confirms the molecular diagnosis and informs tailored management.
2. How is the sample collected?
In Brief: A small amount of whole blood, extracted DNA, or a drop of blood on an FTA card is sufficient; home phlebotomy is available across all emirates. Our ISO-certified VIP mobile phlebotomy team visits your home, office, or hotel from 8 AM to 11 PM daily, transporting samples in validated cold-chain containers.
3. What is the turnaround time and how do I receive results?
In Brief: Typically results are delivered within 3 to 4 weeks via a secure encrypted PDF report, accompanied by a telephonic consultation with our clinical geneticist. The report includes variant classification per ACMG guidelines and actionable recommendations.
UAE Regulatory & Data Privacy Adherence
This service is fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genomic data is processed with strict confidentiality and stored on secure UAE-based servers. DNA Labs UAE operates under DHA Facility License No. 1143 at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | ICK Gene Endocrine-Cerebroosteodysplasia Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Blood Spot Card |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full coding region coverage |
| ICD-10-CM Code | Q87.8 (Other specified congenital malformation syndromes involving multiple systems) |
| LOINC Code | 47365-9 (Genetic analysis) |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians