SDHA Gene Mitochondrial Respiratory Chain Complex II Deficiency Genetic Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

🏆 Precision Genomics at DNA Labs UAE

✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next Generation Sequencing (NGS). Certified INT/EGQ/2509DA/3139.
✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
✓ Clinical Guidance: Telephonic post-test interpretation by DHA-licensed Consultant Medical Genetics.
✓ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This advanced genetic test screens the entire SDHA gene for mutations linked to mitochondrial respiratory chain complex II deficiency—a rare inherited disorder often presenting with neurological deterioration. Available across the UAE with a 3–4 week reporting time, it provides families and clinicians with definitive molecular diagnosis to guide management and reproductive planning.

Feature	Our Test (DNA Labs UAE)	Closest Alternative
Method	Next Generation Sequencing (NGS) — full gene coverage	Single-gene Sanger sequencing (limited sensitivity)
Turnaround Time	3–4 Weeks	6–8 Weeks (many overseas labs)
Sample Type	Whole Blood, Extracted DNA, or FTA Card (1 drop blood)	Whole blood only (cold-chain required)
Clinical Report	DHA-compliant, clinical correlation notes & genetic counselling included	Raw variant list with limited interpretation
Regulatory Assurance	ISO 9001:2015, UAE PDPL & Federal Law No. 2 of 2019 compliant	Variable; often non-local privacy standards

Physician Insight & Safety Protocols

“As a Consultant Medical Genetics dedicated to inherited mitochondrial disorders, I understand the anxiety that accompanies genetic testing. The SDHA gene analysis is a profound step toward clarity, but a positive result does not predict symptom severity and must be interpreted in the full clinical context. Our multidisciplinary team is committed to guiding you through every result, ensuring you never navigate this journey alone.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403

Advisory & Safety Protocol

⚠️ Medication Advisory

Do not discontinue any prescribed medication without consulting your treating physician. This genetic test is for diagnostic clarification only and must not replace ongoing neurological or metabolic management. If you experience sudden vision loss, severe headache, seizures, acute muscle weakness affecting breathing or swallowing, or altered consciousness, seek immediate emergency care.

Exclusion Criteria

Inability to provide informed consent or lack of legal guardian consent for minors (pursuant to Federal Decree-Law No. 4 of 2016 on Medical Liability).
Uncontrolled active infection or severe anemia contraindicating venipuncture.
Insufficient sample volume or compromised DNA integrity after collection.

Patient FAQ & Clinical Guidance

1. What exactly does the SDHA gene test detect?

This genetic test analyzes the entire SDHA gene for pathogenic mutations that cause mitochondrial respiratory chain complex II deficiency, a rare neurometabolic disorder. It confirms a molecular diagnosis, aids prognosis, and guides reproductive options. The test covers all coding exons and splice sites with 99.9% analytical sensitivity.

2. How is the test performed and what sample is needed?

A healthcare professional collects a small blood sample (3–5 mL) via venipuncture; alternatively, a dried blood spot on an FTA card or previously extracted DNA is accepted. No special dietary preparation is required. Our DHA-licensed mobile phlebotomy team visits your home or office between 8 AM and 11 PM, maintaining strict cold-chain transport to our UAE ISO-certified laboratory.

3. What does a positive result mean for my health and family?

A positive result confirms a disease-causing SDHA mutation, indicating mitochondrial complex II deficiency that may require lifelong neurological and metabolic surveillance. The inheritance pattern is autosomal recessive, with a 25% recurrence risk for future pregnancies. Genetic counselling will discuss prenatal or preimplantation genetic testing options.

UAE Regulatory & Data Privacy Adherence

🏛 Legal Compliance: This test is performed in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic data is processed solely within the UAE under ISO 9001:2015 certified protocols (Cert: INT/EGQ/2509DA/3139).

Clinical & Logistical Metadata

Test Name	SDHA Gene Mitochondrial Respiratory Chain Complex II Deficiency Genetic Test
Price (AED)	2,800 AED
Turnaround Time	3–4 Weeks
Sample Type / Matrix	Whole Blood, Extracted DNA, or FTA Card (dried blood spot)
Methodology Used	Next Generation Sequencing (NGS) – Full gene coverage
ICD-10-CM Code	E88.89
LOINC Code	81236-0
DHA Facility License & Address	DHA License No. 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE