Test Price
2,800 AED✅ Home Collection Available
MT-TW Gene Mitochondrial Encephalopathy Genetic Test in UAE
Executive Summary & Core Metrics
- Diagnostic Accuracy: >99.9% diagnostic sensitivity via ISO-certified next‑generation sequencing.
- Logistics Excellence: VIP mobile phlebotomy and temperature‑controlled home collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Post‑test telephone consultation with a DHA‑licensed medical geneticist.
- Insurance Verification: Direct WhatsApp coverage check at +971 54 548 8731.
Test Overview & Methodology
The MT-TW gene encodes mitochondrial tRNATrp, essential for mitochondrial protein synthesis. Pathogenic variants in this gene cause severe, often paediatric‑onset mitochondrial encephalopathy. This definitive genetic test uses next‑generation sequencing (NGS) to analyse the entire MT-TW locus, identifying known and novel mutations for precise diagnosis and family counselling.
| Feature | Our Test (NGS) | Closest Alternative (Sanger/TP‑PCR) |
|---|---|---|
| Precision | >99.9% diagnostic sensitivity, full gene coverage | Limited to selected exons; up to 15% false negatives |
| Methodology | Next‑Generation Sequencing (Illumina®) | Conventional Sanger sequencing |
| Turnaround Time | 3–4 weeks (ISO‑certified lab) | 6–8 weeks (no urgent options) |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
“Mitochondrial encephalopathy can be deeply distressing for families. This NGS assay provides high‑resolution genetic evidence, but it must be integrated with neurological examination, MRI findings, and family history. A positive result confirms the diagnosis; a negative result does not exclude other mitochondrial or metabolic disorders. Clinical correlation remains essential.”
Advisory Precautions
⚠️ Important Safety Notice
Do not discontinue any prescribed medication without consulting your doctor. This genetic test is a diagnostic tool and does not replace emergency medical care.
Exclusion Criteria & Emergency Red Flags
- Acute intercurrent illness with haemodynamic instability – postpone sample collection.
- Inability to provide informed consent (requires legal guardian for minors or unconscious patients).
- Uncontrolled seizure within the last 48 hours – reschedule phlebotomy under medical supervision.
- ER Red Flags: New‑onset confusion, respiratory distress, or sudden loss of consciousness after sampling – seek emergency care immediately.
Pre‑test requirement: A genetic counselling session is mandatory to draw a detailed pedigree of affected family members.
Patient FAQ & Clinical Guidance
1. Who should consider the MT-TW gene encephalopathy test?
Any individual with unexplained progressive neurological symptoms—especially developmental delay, seizures, or muscle weakness—and a family history suggestive of maternal inheritance should consider this test.
2. How is the sample collected, and is home collection available?
A small volume of whole blood, extracted DNA, or a dried blood spot (FTA® card) is required. Our ISO‑certified VIP mobile phlebotomy team performs hospital‑grade home collection daily from 8 AM to 11 PM.
3. What do the results mean, and what should I do next?
A pathogenic variant confirms the diagnosis of MT-TW‑related mitochondrial encephalopathy. Immediately schedule a post‑test clinical guidance session with our DHA‑licensed consultant medical geneticist to discuss management and family screening.
4. Is this test covered by insurance?
Coverage varies by insurer. We provide direct WhatsApp verification at +971 54 548 8731 to confirm your policy details before proceeding.
UAE Regulatory & Data Privacy Adherence
DHA Facility License No.: 1143
All patient data is processed in strict compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Clinical safety and patient consent procedures adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Data is encrypted and processed under secure, audited protocols in accordance with UAE health data governance standards.
Clinical & Logistical Metadata
| Test Name | MT‑TW Gene Mitochondrial Encephalopathy Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood, extracted DNA, or dried blood spot (FTA® card) |
| Methodology Used | Next‑Generation Sequencing (Illumina®) |
| ICD‑10‑CM Code | G31.81, G31.89 |
| LOINC Code | 81247‑9 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians