Test Price
2,800 AED✅ Home Collection Available
MMAB Gene Methylmalonic Aciduria, cblB Type Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited facility using next-generation sequencing (NGS) for full MMAB gene analysis.
VIP Logistics: Temperature-controlled cold-chain home phlebotomy available daily from 8 AM to 11 PM across Dubai, Abu Dhabi, and Sharjah. Secure courier retrieval for blood or FTA card samples.
Clinical Guidance: Post-test telephonic session with board-certified genetic counsellor to interpret results and discuss familial implications.
Insurance Verification: Direct coverage check via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The MMAB gene test employs next-generation sequencing to detect pathogenic variants associated with methylmalonic aciduria, cblB type—a rare autosomal recessive metabolic disorder. This test aids in definitive molecular diagnosis, carrier screening, and family risk assessment, contributing to precision management and genetic counselling in the UAE.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative (Biochemical Assay) |
|---|---|---|
| Methodology | Full Gene NGS with Copy Number Variant Analysis | Urine Organic Acids + Vitamin B12 Loading Test |
| Diagnostic Sensitivity | >99.9% for pathogenic variants | ~85% for biochemical indication |
| Turnaround Time | 3-4 Weeks | 1-2 Weeks |
| Carrier Status Detection | Identifies heterozygous carriers | Cannot detect carriers |
| Price (AED) | 2,800 | ~1,500 |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I emphasize that genetic test results must be contextualized within the full clinical picture, including metabolic markers and family history. A positive variant confirms the diagnosis but does not replace ongoing biochemical monitoring and multidisciplinary management. Always combine molecular findings with clinical and laboratory data for optimal patient care.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Advisory
⚠️ Do not discontinue any prescribed medication or metabolic therapy without direct consultation with your treating physician. This test is a diagnostic aid, not a substitute for ongoing medical management.
Exclusion Criteria & Emergency Red Flags
- Do not schedule this test if the patient is currently experiencing acute metabolic decompensation (vomiting, lethargy, hyperammonemia).
- If the patient has received a blood transfusion within the last 4 weeks, DNA extraction from blood may be compromised; use extracted DNA or buccal swab as alternative.
- Pregnancy is not a contraindication, but genetic counselling is mandatory before testing.
- ER Red Flags: Seek immediate medical attention if after sample collection the patient develops seizures, altered consciousness, or respiratory distress.
Patient FAQ & Clinical Guidance
1. What is the MMAB gene test and why is it performed?
The MMAB gene test identifies pathogenic variants causing methylmalonic aciduria cblB type, a rare metabolic disorder. It is utilized for definitive molecular diagnosis in symptomatic individuals, carrier detection for at-risk family members, and prenatal planning. In the UAE, genetic testing follows the Federal Decree-Law No. 4 of 2016 on Medical Liability and PDPL data protection standards, ensuring informed consent and confidentiality.
2. How is the sample collected, and is a home visit available?
Sample collection is performed via a simple blood draw (peripheral whole blood in EDTA) or using a DNA FTA card from a single drop of blood. A VIP mobile phlebotomy service is available across Dubai, Abu Dhabi, and Sharjah from 8 AM to 11 PM. All collections are conducted under ISO 9001:2015 cold-chain protocols to preserve DNA integrity. Simply contact our team on WhatsApp at +971 54 548 8731 to schedule.
3. What do the results mean and how will I receive them?
Results are delivered in a comprehensive DHA-compliant report within 3-4 weeks, clearly indicating pathogenic, likely pathogenic, or variants of uncertain significance. A board-certified genetic counsellor will schedule a telephonic session to explain the findings, discuss implications for family members, and guide next steps, all in strict adherence to UAE PDPL data privacy laws.
UAE Regulatory & Data Privacy Adherence
- Genetic testing is conducted in strict accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability, mandating pre-test genetic counselling and informed consent.
- All patient data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), ensuring encrypted storage and secure transmission of genetic information.
- Health information processing adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Clinical & Logistical Metadata
| Test Name | MMAB Gene Methylmalonic Aciduria, cblB Type Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3-4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or FTA card (dried blood spot) |
| Methodology Used | Next-generation sequencing (NGS) with copy number variant analysis |
| ICD-10-CM Code | E71.1 |
| LOINC Code | 81404-6 |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians