Also known as: FBN1 Gene Sequencing for Marfan Syndrome
Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3โ4 weeks
FBN1 Gene Marfan Syndrome Genetic Test in UAE | 2800 AED DHA CERTIFIED ISO 9001:2015
Executive Summary & Core Metrics
Secure your cardiovascular future with a definitive FBN1 gene sequencing test for Marfan syndrome. Delivered via Next Generation Sequencing (NGS) with 99.9% diagnostic sensitivity, ISO-certified cold-chain home collection across the UAE. Includes post-test genetic counselling and direct insurance verification. Core metrics: Price 2,800 AED, Turnaround Time 3โ4 weeks, Sample Type: Whole blood or FTA card blood spot.
Test Overview & Methodology
The FBN1 gene test screens for pathogenic variants causing Marfan syndrome, a life-threatening connective tissue disorder affecting the aorta, skeleton, and eyes. Our test uses state-of-the-art Next Generation Sequencing (NGS) with full exon and splice site coverage, including CNV analysis, delivering definitive results within 3 to 4 weeks.
| Feature | Our ISO Lab Test | Conventional Genetic Panel |
|---|---|---|
| Sequencing Method | NGS with CNV analysis (LCโMS/MS grade validation) | Sanger sequencing or limited panel |
| Turnaround Time | 3โ4 weeks | 4โ6 weeks |
| Variant Coverage | Full gene (coding exons ยฑ20 bp intronic boundaries) | Hotspot mutations only |
| Sample Types Accepted | Blood, extracted DNA, or one drop of blood on FTA card | Blood only |
| Price | 2800 AED | 2500โ3500 AED |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics specialist, I recognize the importance of definitive molecular diagnosis for Marfan syndrome. The FBN1 NGS test provides unparalleled accuracy, but results must always be interpreted alongside clinical examination, family history, and echocardiographic findings. Genetic testing is a powerful tool, not a substitute for comprehensive cardiologic surveillance." โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Continuation
Important: Do not discontinue prescribed medication (e.g., beta-blockers, ARBs) without consulting your doctor. This test is for diagnostic clarification and does not replace your current treatment plan.
Exclusion Criteria & Emergency Red Flags
- Pregnant or breastfeeding individuals should defer elective genetic testing unless medically urgent.
- Patients with active hematologic malignancies may have sample quality issues; consult the lab prior to collection.
- This test is intended for germline analysis only; it is not validated for somatic mutation detection.
- Immediate Emergency: If you experience sudden chest or back pain, severe shortness of breath, or signs of aortic dissection, go to the nearest ER immediately. This test does not replace acute medical care.
Patient FAQ & Clinical Guidance
1. What is an FBN1 genetic test, and why is it critical for Marfan syndrome?
This NGS test identifies pathogenic variants in the FBN1 gene responsible for Marfan syndrome, enabling early cardiac surveillance and life-saving preventive intervention. It is essential for confirming a clinical suspicion and guiding family screening.
2. Can I use a simple blood spot on an FTA card instead of a full blood draw?
Yes, our validated protocol accepts one drop of blood on an FTA card, suitable for remote collection and pediatric cases, while maintaining 99.9% sensitivity and specificity.
3. How do I schedule home collection, and will insurance cover this test in the UAE?
Simply WhatsApp +971 54 548 8731 for direct billing verification and arrange VIP mobile phlebotomy between 8 AM and 11 PM, with fast-track insurance pre-approval. Home collection is temperature-controlled and ISO-certified.
UAE Regulatory & Data Privacy Adherence
Data Protection: All genetic data is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety align with Federal Decree-Law No. 4 of 2016 on Medical Liability. Your results remain confidential and are accessible only to authorized healthcare providers.
Clinical & Logistical Metadata
| Test Name | FBN1 Gene Sequencing for Marfan Syndrome |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 weeks |
| Sample Type / Matrix | Whole blood (venous or dried blood spot on FTA card) or extracted DNA VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AMโ11 PM |
| Methodology Used | Next Generation Sequencing (NGS) with CNV analysis, full exon and splice site coverage |
| ICD-10-CM Code | Q87.4 (Marfan syndrome) |
| LOINC Code | 94451-2 (FBN1 gene targeted mutation analysis) |
| DHA Facility License & Laboratory Address | License No. 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. DNA Labs UAE |
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Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
Preparation Required
["Do not discontinue prescribed medication without consulting your doctor."]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians