Test Price
2,800 AED✅ Home Collection Available
LPA Gene (Congenital Deficiency) NGS Genetic Test in Dubai & UAE | 2,800 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity through ISO 9001:2015 accredited NGS sequencing covering the full LPA gene including kringle IV repeats.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
Clinical Guidance: Post-test telephonic clinical guidance and molecular interpretation with our DHA-licensed Consultant Medical Geneticist.
Insurance: Direct billing verification via WhatsApp: +971 54 548 8731
Test Overview & Methodology
The LPA Gene NGS Genetic Test provides definitive molecular confirmation of congenital lipoprotein(a) deficiency by sequencing the entire LPA gene. Unlike standard quantitative Lp(a) assays that only measure circulating protein levels, this test identifies single nucleotide variants, insertions, deletions, and copy number variations that abolish Lp(a) production, distinguishing genetic deficiency from acquired causes.
| Feature | Our Test (NGS) | Standard Lp(a) Blood Level |
|---|---|---|
| Precision | Single-nucleotide resolution across full LPA gene including kringle IV domains | Quantitative immunoassay; no genetic insight |
| Methodology | Next Generation Sequencing (NGS) with full gene coverage | ELISA / Immunoturbidimetry |
| Turnaround Time | 3–4 Weeks | 1–3 Days |
| Clinical Utility | Diagnose congenital deficiency, carrier screening, family risk stratification | CVD risk stratification only |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
“From a medical genetics standpoint, the LPA gene test is a powerful tool for confirming congenital Lp(a) deficiency, but it must be interpreted within the context of a complete lipid profile, Lp(a) mass measurement, and a three-generation family pedigree. I require mandatory pre-test genetic counseling to document clinical history and secure informed consent, ensuring that incidental findings are managed appropriately and that patients understand the implications for family planning.”
Advisory & Safety Considerations
Medication Warning: Do not discontinue any prescribed lipid-lowering, anticoagulant, or antiplatelet therapy without consulting your referring physician. This genetic test provides diagnostic clarification and does not replace ongoing clinical management.
Safety Exclusion Criteria & Emergency Red Flags
- Active febrile illness or suspected systemic infection – postpone collection until complete resolution.
- Known bleeding diathesis, coagulopathy, or severe hematological disorder – inform our phlebotomy team for advanced precautions.
- This is an elective genetic test and is NOT indicated for acute cardiovascular events.
- If you experience sudden chest pain, severe dyspnea, or stroke-like symptoms, call 999 immediately. This test does not diagnose acute myocardial infarction or stroke.
Patient FAQ & Clinical Guidance
1. What does the LPA Gene NGS test detect?
The LPA Gene NGS test identifies pathogenic variants in the LPA gene responsible for congenital lipoprotein(a) deficiency. It detects single nucleotide variants, small insertions and deletions, and large copy number changes with greater than 99% diagnostic sensitivity, confirming the genetic cause of extremely low Lp(a) levels.
2. How should I prepare for this genetic test?
No fasting or special preparation is required. A standard blood sample (2-3 ml EDTA) or a dried blood spot on an FTA card is sufficient. A mandatory pre-test genetic counseling session is required to document family history, review clinical indications, and obtain informed consent. Please bring any prior lipid profiles and physician referral forms.
3. Who should consider the LPA congenital deficiency test?
Individuals with repeatedly very low Lp(a) levels (<10 nmol/L), a family history of congenital Lp(a) deficiency, or unexplained cardiovascular risk in the setting of low Lp(a) should consider this test. Pediatricians order it for neonates with suspected inborn errors of lipoprotein metabolism, while general physicians and geneticists use it for adult familial screening and cascade testing.
UAE Regulatory & Data Privacy Adherence
Your genetic data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety, patient consent, and medical liability adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE operates under DHA Facility License 1143 and is ISO 9001:2015 certified for quality management in genetic diagnostics.
Clinical & Logistical Metadata
| Test Name | LPA Gene (Congenital Deficiency) NGS Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 21 – 28 Days |
| Sample Type / Matrix | Whole Blood (EDTA) or Dried Blood Spot (FTA Card) |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | E78.9 (Disorder of lipoprotein metabolism, unspecified), Z13.22 (Encounter for screening for metabolic disorder) |
| LOINC Code | 94514-9 |
| DHA Facility License & Laboratory Address | DHA License 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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