Test Price
2,800 AED✅ Home Collection Available
PAX5 Germline Mutation Susceptibility Test for Acute Lymphoblastic Leukemia (NGS) in UAE – 2,800 AED
Executive Summary & Core Metrics
TRUST Executive Summary
- Accuracy Guarantee: 99.9% diagnostic sensitivity for clinically significant PAX5 germline variants, delivered via ISO 9001:2015‑accredited NGS with Sanger confirmation.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Complimentary post‑test telephonic interpretation by a DHA‑licensed genetic counsellor.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This advanced NGS‑based test screens your DNA for inherited mutations in the PAX5 gene that markedly increase the lifetime risk of developing acute lymphoblastic leukemia (ALL), guiding early surveillance and family risk management.
| Feature | Our Test (NGS Full‑Gene Sequencing) | Closest Alternative (Single‑Site PCR) |
|---|---|---|
| Precision | ≥99.9% sensitivity with deletion/duplication analysis | Detects only specific common variants; misses rare mutations |
| Method | Next Generation Sequencing + Sanger validation | PCR‑based genotyping (limited targets) |
| Turnaround | 21–28 Days (3–4 Weeks) | 2–3 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh – Consultant Medical Genetics (DHA Registration ID: 9294403) shares:
“A PAX5 germline result must be interpreted in the context of your complete personal and family pedigree. This test reveals inherited predisposition, not active malignancy. A positive finding enables targeted surveillance protocols that can significantly improve long‑term outcomes. Clinical correlation with complete haematological work‑up remains essential.”
Clinical Advisory & Medication Safety
⚠️ Safety Advisory
Never discontinue, alter, or pause any prescribed medication without explicit consultation with your treating physician. This genetic test provides risk information only and does not replace ongoing clinical management or emergency care.
Exclusion Criteria & Emergency Red Flags
⚠️ Exclusion & Emergency Indicators
- Exclusion Criteria: Individuals under 18 years of age without court‑authorized guardian consent. Testing during pregnancy requires prior genetic counselling for informed decision‑making.
- Emergency Red Flags: Sudden unexplained fever, easy bruising, bleeding gums, or severe bone pain may indicate active leukaemia and warrant immediate emergency department evaluation.
Patient FAQ & Clinical Guidance
1. What does the PAX5 gene mutation test detect?
A: It identifies hereditary PAX5 gene changes that raise the chance of developing acute lymphoblastic leukemia.
This comprehensive NGS analysis scans the entire coding region of PAX5, revealing both point mutations and large deletions that are passed through families and correlate with elevated ALL susceptibility.
2. How is the sample collected and what is the turnaround time?
A: A DHA‑registered phlebotomist collects your blood sample at home via VIP Mobile Phlebotomy, and results are delivered within 21–28 days.
We dispatch a licensed nurse with a temperature‑controlled cold‑chain kit. Alternatively, pre‑extracted DNA or a dried blood spot on an FTA card may be submitted. Results are released through our secure patient portal.
3. What happens if my test result is positive?
A: A positive result triggers immediate clinical referral for lifelong surveillance and cascade testing of first‑degree relatives.
You will be connected to a DHA‑licensed haematologist‑oncologist who will design a personalised monitoring plan including periodic blood counts and imaging. Family members can undergo cascade testing under dedicated genetic counselling.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection: This service operates under DHA Facility License No. 1143 and adheres to Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability. All genetic data is handled with strict confidentiality and encrypted storage.
Clinical & Logistical Metadata
| Test Name | PAX5 Germline Mutation Susceptibility Test for Acute Lymphoblastic Leukemia (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 21–28 Days (3–4 Weeks) |
| Sample Type / Matrix | Peripheral Whole Blood – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily 8 AM – 11 PM) |
| Methodology Used | Next Generation Sequencing (NGS) with Sanger Confirmation |
| ICD-10-CM Code | Z15.02 |
| LOINC Code | 81262-0 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians