Test Price
1,600 AED✅ Home Collection Available
NPM1 & FLT3 Mutation Analysis in UAE | 1600 AED | 2026 DHA Guidelines
تحليل طفرات NPM1 و FLT3 في الإمارات | 1600 درهم | معتمد من هيئة الصحة بدبي 2026
Executive Summary (الملخص التنفيذي)
- Diagnostic Precision: 99.9% Diagnostic Sensitivity through ISO 9001:2015 Accredited Sequencing, ensuring unambiguous detection of NPM1 and FLT3 mutations relevant to acute myeloid leukemia (AML) prognosis.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO-Certified Cold-Chain Home Collection, with VIP Mobile Phlebotomy available 8 AM–11 PM across all Emirates.
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance to interpret results with your treating physician.
- Insurance & Billing: Direct Billing Verification and pre-approval via WhatsApp at +971 54 548 8731.
- UAE Compliance: Fully compliant with Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), and UAE PDPL Data Privacy standards.
ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر معالجة معتمدة بمعيار ISO 9001:2015. خدمة سحب منزلي متميزة عبر سلسلة تبريد معتمدة ونظام سحب النُخاع المتنقلة. إرشادات سريرية هاتفية بعد الفحص.
Overview
NPM1 & FLT3 Mutation Analysis is a high-precision Sanger Sequencing assay designed to detect somatic mutations in the nucleophosmin 1 (NPM1) and fms-related tyrosine kinase 3 (FLT3) genes from bone marrow or peripheral blood. This test is essential for risk stratification and therapeutic decision-making in acute myeloid leukemia (AML), as these mutations directly inform prognosis and eligibility for targeted therapies. تحليل طفرات NPM1 و FLT3 هو فحص تسلسل جيني عالي الدقة لتحديد الطفرات في نخاع العظم أو الدم المحيطي، وهو أساسي لتقسيم مخاطر ابيضاض الدم النقوي الحاد واتخاذ قرارات العلاج الموجه.
| Parameter | Our NPM1 & FLT3 Test | Closest Alternative (NGS Panel) |
|---|---|---|
| Methodology | Sanger Sequencing (Gold Standard for targeted mutations) | Next-Generation Sequencing (broad gene panel) |
| Analytical Sensitivity | Detection limit ~5% variant allele frequency | Varies ~2-5% depending on coverage |
| Turnaround Time | 7–8 working days | 10–14 working days (typical) |
| Cost (AED) | 1600 | 2500–4000 |
| DHA Compliance | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Variable |
Physician Insight & Safety Protocol
"As a consultant with over two decades of experience, I consider NPM1 and FLT3 testing indispensable for every newly diagnosed AML patient. These mutations are not only prognostic but directly guide the use of modern targeted agents. However, I always interpret these results alongside the full clinical picture, including bone marrow morphology and patient performance status, because no standalone biomarker can replace holistic judgement." — Dr. PRABHAKAR REDDY, Consultant Hematologist, DHA License 61713011
⚠️ Medication Warning: Do not discontinue prescribed medication or modify your treatment plan based solely on these results. Always consult your haematologist or oncologist.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusions: This test requires a physician's prescription; it is not intended for routine screening, surgery clearance, pregnancy evaluation, or travel certification without clinical suspicion of haematologic malignancy.
- Red Flags (seek immediate emergency care): Sudden onset of severe fatigue, pallor, unexplained bruising/bleeding, persistent fever >38.3°C, bone pain, or night sweats. These may indicate acute leukaemia and require urgent evaluation, not just genetic testing.
- Sample Stability: Bone marrow or peripheral blood must be transported immediately in appropriate EDTA or heparin tubes to ensure RNA/DNA integrity. Delays beyond 24 hours may compromise results.
Patient FAQ & Clinical Guidance
Q: What exactly does the NPM1 and FLT3 mutation test reveal about my leukaemia?
Direct Answer: This test identifies specific genetic changes in your leukemic cells that predict how aggressive your disease is and which targeted treatments will work best. يكشف هذا الفحص عن التغيرات الجينية في خلايا ابيضاض الدم والتي تتنبأ بمدى عدوانية المرض وأفضل العلاجات الموجهة المناسبة.
Q: Is the bone marrow collection painful, and can it be done at home?
Direct Answer: Bone marrow aspiration is performed under local anaesthesia by a specialist, causing mild discomfort; we offer VIP home collection with strict cold-chain for your convenience. يتم سحب نخاع العظم تحت التخدير الموضعي بواسطة أخصائي مع إحساس خفيف بعدم الراحة؛ نوفر خدمة السحب المنزلي المتميزة مع سلسلة تبريد صارمة.
Q: Can I use this test result to travel or for surgery clearance?
Direct Answer: No, this is solely for clinical decision-making in suspected or confirmed haematologic cancers; it is not valid for travel or preoperative assessment. لا، هذا الفحص مخصص فقط لاتخاذ القرارات السريرية في حالات السرطانات الدموية المشتبهة أو المؤكدة؛ لا يصلح للسفر أو التقييم قبل الجراحة.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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