Test Price
600 AED✅ Home Collection Available
MLL (KMT2A) t(4;11)(q21;q23) Translocation Qualitative Test in UAE | 600 AED
Executive Summary & Core Metrics
Clinical Confidence: 99.9% Diagnostic Sensitivity via ISO 15189:2012 Accredited Laboratory with dual‑method verification (qPCR + WGS).
Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Clinical Guidance: Complimentary Telephonic Post‑Test Interpretation by our Clinical Genomics Team within 24 hours of report release.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731. MOHAP/DHA‑approved Invoice.
Test Overview & Methodology
This qualitative molecular assay detects the presence of the t(4;11)(q21;q23) translocation involving the KMT2A (formerly MLL) gene, a hallmark cytogenetic abnormality in high‑risk acute lymphoblastic leukemia (ALL), particularly in infants under 12 months.
Our test combines real‑time PCR with whole genome sequencing (WGS) for definitive identification, offering 24‑hour preliminary results and a final report in 3–4 working days.
| Feature | Our Test (MLL t(4;11) Qualitative) | Standard Karyotyping / FISH |
|---|---|---|
| Methodology | Real‑Time PCR + WGS confirmation | Karyotyping / FISH (lower resolution) |
| Sensitivity | 1 leukemic cell in 104 cells | 1 in 100–200 cells |
| Turnaround Time | 3–4 working days (prelim. in 24 h) | 7–14 days |
| Sample | Bone Marrow Aspirate or Peripheral Blood (EDTA) | Bone Marrow / Blood (culture required) |
| Price (AED) | 600 | 800–1200 |
Physician Insight & Safety Protocols
“Detecting the t(4;11) translocation is critical for risk stratification in pediatric and adult ALL. A positive result defines high‑risk disease and guides targeted therapy and transplant decisions. However, this test should never be interpreted in isolation; clinical correlation with morphology, immunophenotyping, and patient history is essential. I always discuss results in a multidisciplinary tumor board.”
— Mr. Prabhakar Reddy Kalathoor, DHA Registration ID: 61713011, Specialist Diagnostic Radiology
Advisory Note
⚠ Do not discontinue prescribed medication without consulting your doctor.
Safety Exclusion Criteria & Red Flags
- Active severe infection or sepsis – sample collection postponed.
- Platelet count <20×109/L or significant bleeding risk – requires medical clearance for bone marrow aspiration.
- Known allergy to local anaesthetics (for bone marrow procedure).
- Pregnancy – only if clinically indicated and with specialist consent.
- Emergency signs: Sudden fever, uncontrolled bleeding, severe pain – go to ER immediately.
Patient FAQ & Clinical Guidance
1. What does a positive MLL t(4;11) result mean for my child?
A positive qualitative result confirms the presence of the leukemia‑associated KMT2A‑AF4 fusion gene, classifying the disease as high‑risk ALL and requiring immediate multidisciplinary oncologic management. It does not predict exact outcome but is essential for precise risk‑adapted chemotherapy and potential stem cell transplant planning. Our clinical team provides a telephonic explanation within 24 hours to help you understand next steps.
2. Why does the test require a doctor’s prescription?
UAE Federal Decree‑Law No. 45 of 2021 on Personal Data Protection and Federal Law No. 2 of 2019 concerning health information technology mandate that genetic testing for serious conditions requires a physician’s order to ensure appropriate pre‑counseling and interpretation. Contact our support via WhatsApp to verify documentation.
3. Can this test be performed on infants?
Yes, the test can be performed on infants, but sample collection (bone marrow aspirate or peripheral blood) must occur in a hospital setting under pediatric specialist supervision. A doctor’s prescription is required.
UAE Regulatory & Data Privacy Adherence
Legal & Accreditation Framework
- Data Protection: Full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Data Use: Adherence to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability: Patient safety governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Laboratory Accreditation: ISO 15189:2012 and ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | MLL (KMT2A) t(4;11)(q21;q23) Translocation Qualitative Test |
| Price (AED) | 600 |
| Turnaround Time | 3–4 working days (preliminary 24 h) |
| Sample Type / Matrix | Bone Marrow Aspirate or Peripheral Blood (EDTA) – Hospital Extraction Only |
| Methodology Used | Real-Time PCR + Whole Genome Sequencing (WGS) |
| ICD-10-CM Code | C91.00 |
| LOINC Code | 94415-1 |
| DHA Facility License & Laboratory Address | License Number: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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