Test Price
800 AED✅ Home Collection Available
TEL/AML1 (ETV6-RUNX1) Fusion Quantitative PCR Test in UAE | 800 AED | 2026 DHA Guidelines
تحليل TEL/AML1 الكمي في الإمارات | 800 درهم | معتمد من هيئة الصحة بدبي
Clinical Excellence Guarantee
- 99.9% Diagnostic Sensitivity via ISO Accredited Real-Time qPCR & WGS.
- Methodology: Real-Time PCR (qPCR) and Whole Genome Sequencing (WGS) for MRD monitoring.
Premium Patient Logistics
- VIP Mobile Phlebotomy: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain (8 AM - 11 PM).
- Post-Test Clinical Guidance: Complimentary telephonic interpretation by a clinical expert.
Insurance & Compliance
Direct Billing Verification: Check your coverage instantly via WhatsApp +971 54 548 8731. Test requires a Doctor's prescription; not applicable for surgery, pregnancy, or travel clearance. Fully compliant with UAE PDPL and Federal Decree-Law No. 41 of 2024 (Art. 87) for minor consent.
Test Overview & Comparative Precision
The TEL/AML1 fusion transcript, resulting from t(12;21)(p13;q22), is the most frequent genetic abnormality in childhood B-cell precursor acute lymphoblastic leukemia (ALL). Early and precise quantification is a cornerstone of risk stratification and minimal residual disease (MRD) monitoring. يُعدّ تقدير كمية جين الاندماج TEL/AML1 العلامة الجزيئية الأكثر شيوعًا لتقسيم مخاطر سرطان الدم الليمفاوي الحاد ومراقبة المرض المتبقي بأدنى حد له.
| Feature | Our Test (TEL/AML1 qPCR) | Closest Alternative (FISH) |
|---|---|---|
| Analytical Precision | Sensitivity down to 1 in 10⁴ cells (0.01%) | Sensitivity limit ~1-5% |
| Methodology | Real-Time PCR (qPCR) & WGS | Fluorescence In Situ Hybridization |
| Turnaround Time | 3-4 Days | 7-10 Days |
| MRD Monitoring Utility | Gold Standard for dynamic monitoring | Limited to baseline diagnosis |
*Specimen: Bone Marrow or Peripheral Blood (Transport immediately in cold-chain). Do not delay transport.
Physician Insight & Clinical Safety Protocol
"As clinicians, a positive TEL/AML1 result, while often associated with a favorable prognosis in pediatric ALL, must always be correlated with comprehensive cytogenetics and clinical presentation. I advise parents that this quantitative PCR test is a powerful tool for tracking treatment efficacy, and we are available to interpret the log reduction values post-result to provide absolute clarity on their child’s treatment response trajectory."
— Dr. PRABHAKAR REDDY, Clinical Consultant (DHA License: 61713011)
⚠ Critical Medication Warning
Do not discontinue or modify any prescribed chemotherapy, corticosteroid, or supportive medication without explicit consultation with your treating oncologist. Alterations in medication status can affect MRD levels and clinical stability.
Exclusion Criteria & ER Red Flags
- Specimen clotted, hemolyzed, or volume insufficient for RNA extraction.
- Collection tube not immediately placed in cold-chain or delay > 2 hours.
- Patient on active antibiotic therapy for unrelated infection; reschedule if possible.
- Seek immediate emergency care if the patient develops fever > 38.3°C, unexplained bleeding, or severe respiratory distress.
Patient FAQ & Clinical Guidance
Why is monitoring TEL/AML1 with quantitative PCR more informative than a standard blood smear during leukemia remission?
Quantitative PCR detects one leukemic cell among 10,000 normal cells, providing a molecular-level measure of residual disease that standard morphology cannot see. يكتشف تفاعل البوليميراز المتسلسل الكمي خلية سرطانية واحدة بين 10,000 خلية طبيعية، مما يعطي قياسًا جزيئيًا للمرض المتبقي لا يمكن للفحص المجهري القياسي رؤيته.
If my child’s report shows a log reduction of 4 from the baseline diagnosis after induction therapy, what does this mean clinically?
A 4-log reduction signifies a excellent early response, classifying the patient in the low-risk MRD category and generally predicting a favorable long-term prognosis for pediatric ALL. انخفاض بمقدار 4 لوغاريتمات يعني استجابة مبكرة ممتازة، مما يصنف المريض في فئة المرض المتبقي منخفض الخطورة ويتنبأ عمومًا بتوقعات جيدة على المدى الطويل لسرطان الدم الليمفاوي الحاد لدى الأطفال.
What are the pre- preparation requirements for a TEL/AML1 bone marrow aspiration, and how is home collection performed?
A doctor’s prescription is mandatory, and the specimen must be collected via our DHA-licensed phlebotomist and transported immediately in a validated cold-chain kit to preserve RNA integrity. وصفة الطبيب إلزامية، ويجب جمع العينة بواسطة أخصائي سحب الدم المرخص لدينا ونقلها فورًا في صندوق تبريد معتمد للحفاظ على سلامة الحمض النووي الريبي.
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