JAK2 Gene Familial Thrombocytosis NGS Test in UAE | 2800 AED | DNA Labs UAE

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-accredited NGS processing, compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.

Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM). Sample options: Whole Blood, Extracted DNA, or FTA Card.

Clinical Guidance: Post-Test Genetic Counseling session with a DHA-licensed Consultant Medical Genetics included.

Insurance & Billing: Direct Billing Verification via WhatsApp at +971 54 548 8731. DHA Facility License: 1143.

Test Overview & Methodology

The JAK2 gene familial thrombocytosis NGS test comprehensively sequences the JAK2 gene to detect inherited and acquired mutations linked to essential thrombocythemia and other myeloproliferative neoplasms. This next-generation sequencing approach replaces older single-mutation PCR, offering clinicians and patients in the UAE a definitive molecular diagnosis aligned with international precision medicine standards.

Feature	Our Test (JAK2 NGS)	Closest Alternative (JAK2 V617F PCR)
Precision / Sensitivity	>99.9% – full gene sequencing	~95% – single hotspot only
Methodology	NGS (Next‑Generation Sequencing)	Allele‑Specific PCR
Turnaround Time	3–4 Weeks	1–2 Weeks
Mutations Detected	V617F, exon 12, and rare variants	V617F only
Price	2800 AED	~1500–2000 AED

Physician Insight & Safety Protocols

Clinical Note from Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA ID: 9294403): “As a clinical geneticist, I rely on comprehensive JAK2 NGS to differentiate familial thrombocytosis from reactive conditions and to guide prognostic discussions. A positive result must be interpreted in concert with a full blood count and bone marrow evaluation. Never alter or discontinue any prescribed medication without direct consultation with your treating physician—abrupt changes in anti‑platelet or cytoreductive therapy can carry serious thrombotic or hemorrhagic risks.”

Medication & Clinical Advisory

Do not stop or adjust any prescribed medication before the test without consulting your treating physician. Abrupt changes in anti‑platelet or cytoreductive therapy can lead to severe thrombotic or hemorrhagic complications. If you experience sudden chest pain, shortness of breath, severe headache, vision changes, or unilateral limb swelling, seek immediate emergency care.

Eligibility & Consent Requirements

This genetic test is intended for individuals with persistent unexplained thrombocytosis (>450×10⁹/L), a family history of myeloproliferative neoplasms, or suspicion of JAK2 mutation‑associated disorders. It is not recommended for asymptomatic screening without a clinical indication. In compliance with Federal Decree‑Law No. 4 of 2016 on Medical Liability, testing of minors requires legal guardian consent and a paediatric haematologist referral.

Patient FAQ & Clinical Guidance

1. What is the JAK2 gene test used for?

The JAK2 gene NGS test detects inherited and acquired mutations in the JAK2 gene that cause familial thrombocytosis and myeloproliferative neoplasms. It provides a comprehensive molecular diagnosis to guide therapy and family screening, exceeding the scope of single‑variant PCR assays.

2. How is the sample collected and what options are available?

Sample collection is performed by a DHA‑licensed phlebotomist during a home visit via our VIP Mobile Phlebotomy service. You may provide a standard whole blood sample, pre‑extracted DNA, or a single drop of blood on an FTA card. All specimens are transported using ISO‑certified temperature‑controlled cold‑chain logistics to ensure molecular integrity from collection to laboratory.

3. What is the turnaround time and total cost?

Turnaround time for the JAK2 NGS test is 3 to 4 weeks from sample receipt. The total investment is 2800 AED, inclusive of home collection, a formal genetic counseling session, and post‑result clinical guidance. Insurance verification and direct billing can be initiated via WhatsApp at +971 54 548 8731.

UAE Regulatory & Data Privacy Adherence

Our Commitment to Regulatory Compliance

Data Privacy: We strictly adhere to Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL). Your genetic data is encrypted, securely stored, and never shared without explicit informed consent.
Health ICT Regulation: Our digital health infrastructure complies with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring secure telemedicine and data transmission.
Medical Liability: Patient safety and informed consent protocols are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Accreditations: DNA Labs UAE is an ISO 9001:2015 certified laboratory (Certificate: INT/EGQ/2509DA/3139), operating under DHA Facility License No. 1143 located in Dubai Healthcare City.

Clinical & Logistical Metadata

Test Name	JAK2 Gene Familial Thrombocytosis NGS Test
Price (AED)	2,800 AED
Turnaround Time	3–4 Weeks
Sample Type / Matrix	Whole Blood, Extracted DNA, or FTA Card (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection)
Methodology Used	Next-Generation Sequencing (NGS)
ICD-10-CM Code	D47.3 (Essential thrombocythemia), Z82.1 (Family history of neoplasms)
LOINC Code	92819-1 (JAK2 gene mutation analysis)
DHA Facility License & Address	License No: 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE