Test Price
2,800 AED✅ Home Collection Available
TMPRSS6 Gene Analysis for Iron-Refractory Iron Deficiency Anemia (IRIDA) via NGS in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين TMPRSS6 لفقر الدم الناجم عن نقص الحديد المقاوم للعلاج بالحديد في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing. Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy. Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation. Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
يقدم هذا الفحص الجيني الدقيق تشخيصًا موثوقًا لفقر الدم الناجم عن نقص الحديد المقاوم للعلاج بالحديد (IRIDA) باستخدام تقنية التسلسل المتقدم المتوافقة مع معايير هيئة الصحة بدبي لعام 2026. الدقة المعتمدة، النقل المبرد، والإرشاد السريري يضمن تجربة آمنة ونتائج قابلة للتنفيذ.
Clinical Overview
The TMPRSS6 Gene Analysis for IRIDA is a definitive next-generation sequencing (NGS) test that identifies pathogenic variants in the TMPRSS6 gene, the principal cause of iron-refractory iron deficiency anemia. This test replaces invasive bone marrow exams and repeated iron trials with a single, high-resolution genetic answer, enabling personalized treatment and family screening. Bilingual reporting and DHA-aligned protocol ensure the highest diagnostic confidence for UAE patients.
| Feature | Our Test (TMPRSS6 NGS) | Closest Alternative (Serum Ferritin & Iron Studies) |
|---|---|---|
| Diagnostic Precision | >99.9% sensitivity for TMPRSS6 variants | Indirect; cannot differentiate IRIDA from classic iron deficiency |
| Methodology | High-depth NGS with full gene coverage | Biochemical assays; non-genetic |
| Turnaround Time | 3 to 4 Weeks | 1–3 Days |
| Clinical Utility | Confirms IRIDA, guides cessation of futile iron therapy, enables family screening | Often leads to misdiagnosis and prolonged iron overload risk |
Physician Insight & Safety Protocol
“This NGS panel uncovers the precise genetic basis of your refractory anemia. While the result offers clarity, I emphasize that clinical correlation with your hematologist remains paramount. Please do not alter any prescribed regimen without a thorough consultation.” — Dr. PRABHAKAR REDDY (DHA License: 61713011), Consultant Hematologist.
⚠️ Critical Medication Warning: Do not discontinue prescribed medication or iron supplementation without consulting your doctor. Abrupt cessation may destabilize your hematological status.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Children under 18 years require explicit pediatrician authorization and guardian consent per CDS Law 2026; acute febrile illness or active infection; known bleeding diathesis not controlled.
- Emergency Red Flags After Blood Collection: Sudden severe pallor, difficulty breathing, chest pain, or syncope require immediate medical attention at the nearest emergency department.
Patient FAQ & Clinical Guidance
1. What is the TMPRSS6 genetic test for iron-refractory anemia?
It is a next-generation sequencing test that identifies mutations in the TMPRSS6 gene causing iron-refractory iron deficiency anemia, enabling precise diagnosis and personalized treatment planning. This test directly detects the genetic defect that prevents the body from absorbing oral iron effectively, distinguishing IRIDA from common iron deficiency and avoiding unnecessary iron infusions. Results assist hematologists in targeting alternative therapies such as intravenous iron or novel agents.
2. How is the sample collected and what is the home collection process?
A certified phlebotomist visits your home between 8 AM and 11 PM to collect 2–3 mL of whole blood in a special DNA stabilization tube, ensuring cold-chain transport. Alternatively, you may provide a dried blood spot on an FTA card. The sample is sent to our ISO-certified molecular laboratory under strict chain-of-custody, and you receive a notification when processing begins. The VIP mobile service is available across all seven emirates.
3. How do I interpret my results and what are the next steps?
Your report will detail any pathogenic variant, its zygosity, and clinical significance, accompanied by a post- telephonic consultation with a hematologist. A positive finding confirms IRIDA, guiding the cessation of oral iron and initiation of targeted management. A negative result may still warrant further hematological workup. Genetic counselling is included for family planning and cascade screening of relatives.
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Available in Arabic, English, Hindi & Urdu
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All reports reviewed by DHA-Certified physicians