Test Price
450 AED✅ Home Collection Available
Immunophenotyping by Flow Cytometry (CD45) Test in UAE | 450 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM–11 PM). For bone marrow extraction, collection is strictly hospital-only.
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed specialists.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
Immunophenotyping by Flow Cytometry (CD45) is a high-precision laboratory test that identifies and quantifies immune cell populations in blood or bone marrow using fluorescent-labeled antibodies against CD45, a pan-leukocyte marker. The methodology employs multicolor Fluorescent-Activated Cell Sorting (FACS) with CD45 gating to achieve simultaneous 10–12 marker analysis per cell, delivering >99% diagnostic sensitivity for leukemia/lymphoma subtyping, minimal residual disease (MRD) detection, and immunodeficiency quantification.
| Parameter | Our Test (Immunophenotyping CD45) | Closest Alternative (Immunohistochemistry) |
|---|---|---|
| Diagnostic Precision | Simultaneous 10–12 marker analysis per cell, >99% sensitivity | Semiquantitative, 3–4 markers, prone to observer bias |
| Methodology | Multicolor Flow Cytometry (FACS) with CD45 Gating | Tissue-based staining, manual scoring |
| Turnaround Time | Same Day (if sample received by 9 AM) | 2–3 business days |
| Clinical Utility | Leukemia/lymphoma subtyping, MRD detection, immunodeficiency quantification | Limited to tumor-marker expression on tissue sections |
Physician Insight & Safety Protocols
“As a DHA-licensed Specialist Diagnostic Radiology (ID: 61713011), I emphasize that immunophenotyping by flow cytometry must always be interpreted in conjunction with complete blood counts, bone marrow morphology, and clinical findings. While the test is exquisitely sensitive for clonality and lineage assignment, it should never replace comprehensive histopathological examination in cancer diagnosis. Please share all relevant clinical details to guide accurate gating and analysis.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology
Patient Safety & Advisory Precautions
Immunosuppressive therapies may affect leukocyte counts and surface marker expression. Patients should inform the laboratory and their physician about all current medications prior to sample collection. Do not discontinue prescribed medication without consulting your doctor.
Specimen Handling & Exclusion Criteria
- ER Red Flags: Profound cytopenias (Hb <7 g/dL, Platelets <20×10⁹/L), active bleeding, or hemodynamic instability should be managed in hospital before elective testing.
- Exclusion Criteria: Inability to provide a valid sample due to severe hypovolemic shock, ongoing high-dose anticoagulant therapy that cannot be paused, or documented allergic reaction to heparin (green-top tube).
- Specimen Integrity: Venous blood samples must be kept at 18–22°C and transported immediately. Do not refrigerate or freeze. Use lavender (EDTA) and green (sodium heparin) tubes. For bone marrow extraction: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Patient FAQ & Clinical Guidance
1. What does the CD45 immunophenotyping test detect, and how is it used in cancer care?
Flow cytometric CD45 immunophenotyping precisely identifies abnormal lymphoid or myeloid populations using a pan-leukocyte gate, enabling accurate leukemia and lymphoma classification, minimal residual disease monitoring, and immune reconstitution assessment post-transplant.
2. How should I prepare for the blood or bone marrow collection, and what are the critical transport conditions?
No fasting is required; simply provide a brief clinical history and medication list, while ensuring the laboratory receives the tubes at 18–22°C within 2 hours to preserve leukocyte viability for accurate CD45 gating. For bone marrow samples, collection must be performed in a hospital setting.
3. Are there any special regulatory protections for minors undergoing this in the UAE?
For minors, UAE Federal Law mandates documented parental or guardian consent before sample collection. All pediatric immunophenotyping data is safeguarded under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning health ICT use.
UAE Regulatory & Data Privacy Adherence
All immunophenotyping procedures comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Data is encrypted and stored within UAE sovereign infrastructure.
Clinical & Logistical Metadata
| Test Name | Immunophenotyping by Flow Cytometry (CD45) |
| Price (AED) | 450 AED |
| Turnaround Time | Same Day (if sample received by 9 AM) |
| Sample Type / Matrix | Peripheral blood (EDTA or sodium heparin) or bone marrow aspirate (heparin). Hospital extraction required for bone marrow. |
| Methodology Used | Multicolor Fluorescent-Activated Cell Sorting (FACS) with CD45 Gating |
| ICD-10-CM Code | C81-C96 (Malignant neoplasms of lymphoid, hematopoietic and related tissue) |
| LOINC Code | 14198-2 (Flow cytometry immunophenotyping panel - Blood) |
| DHA Facility License & Laboratory Address | Facility License: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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