Test Price
850 AED✅ Home Collection Available
Immunophenotyping by Flow Cytometry: Kappa and Lambda Light Chains in UAE | 850 AED
Executive Summary & Core Metrics
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM–11 PM. Bone marrow collection: hospital extraction only.
- Clinical Guidance: Telephonic post-test interpretation provided by our specialist diagnostics team.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This highly sensitive flow cytometry assay quantifies kappa and lambda immunoglobulin light chain expression on B-cells, used to detect clonality in lymphoproliferative disorders. It provides same‑day reports with 99.9% diagnostic sensitivity when samples are received by 9 AM, supporting timely clinical management in oncology and hematology.
| Feature | Our Test (Flow Cytometry) | Closest Alternative (IHC / Routine Histology) |
|---|---|---|
| Methodology | Fluorescent Flow Cytometry (LC‑MS/MS validated) | Immunohistochemistry (qualitative) |
| Diagnostic Precision | 99.9% sensitivity & clonality assessment with kappa/lambda ratio | Limited clonality, lower sensitivity (~85%) |
| Turnaround Speed | Same‑day (sample by 9 AM) | 3–5 working days |
| Clinical Utility | Differentiates reactive vs. malignant B‑cell populations; minimal residual disease | Morphology-based; cannot reliably quantify light chain restriction |
Sample Collection & Pre‑Test Information
- Specimen: 3 mL (2 mL min.) whole blood in Lavender Top (EDTA) tube AND 3 mL (2 mL min.) whole blood in Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) bone marrow in Green Top (Sodium Heparin) tube. Bone marrow collection is a hospital‑only procedure.
- Critical Transport: Ship immediately at 18–22°C. DO NOT REFRIGERATE OR FREEZE.
- Documentation: Specify time, date, and clinical details on test request form. Provide brief clinical history.
- Medication Note: Inform the laboratory of any immunosuppressive or chemotherapeutic agents that may influence white cell counts.
Physician Insight & Safety Protocols
“As a DHA‑licensed specialist in diagnostic radiology (DHA Registration: 61713011), I emphasize that flow cytometry immunophenotyping is a key complementary tool to imaging in the diagnosis and staging of lymphoproliferative disorders. The kappa/lambda ratio provides critical information on clonality that, when combined with CT, MRI, or PET/CT findings, guides precise therapeutic planning. Results must always be interpreted in conjunction with clinical history and molecular markers.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology (DHA: 61713011)
Safety & Exclusion Criteria
- Exclusion: Active bleeding disorder, hemodynamic instability, severe anemia (Hb < 7 g/dL) – collection only after medical clearance.
- Do not discontinue any prescribed medication without consulting your doctor.
- Emergency Red Flags: If you develop fainting, uncontrolled bleeding, rapid swelling, or severe pain at the puncture site, seek immediate medical attention.
- Patients under 18 years: guardians must provide consent per Federal Decree‑Law No. 4 of 2016 on Medical Liability; home collection for minors is conducted with guardian presence.
Advisory: Medication Influence on B‑Cell Markers
Certain immunosuppressants, corticosteroids, and chemotherapy agents can alter B‑cell populations and light chain expression. Please provide a full medication list at booking to ensure accurate interpretation of the kappa/lambda ratio.
Patient FAQ & Clinical Guidance
1. What is the purpose of kappa/lambda light chain immunophenotyping?
This test detects clonal B-cells by measuring kappa/lambda light chain expression in blood or marrow. It helps differentiate reactive polyclonal expansions from malignant B-cell lymphomas such as chronic lymphocytic leukemia, mantle cell lymphoma, and plasma cell myeloma. The kappa/lambda ratio is a sensitive marker of clonality and is used for diagnosis, classification, and monitoring minimal residual disease.
2. Is fasting required for this test?
Fasting is not required; inform your physician of immunosuppressant drugs that may affect lymphocyte counts. Certain medications like corticosteroids, chemotherapy agents, or monoclonal antibody therapies can alter B‑cell proportions and light chain expression. Please share your complete medication list during booking to ensure accurate interpretation.
3. How quickly will I receive my results?
Our lab reports same-day if sample arrives by 9 AM, enabling urgent clinical hematology-oncology decisions. Specimens are processed using automated flow cytometry with dual-laser analysis; reports are verified by a consultant pathologist and released through our secure patient portal or WhatsApp. Batches after the cutoff time are processed the next morning, but urgent results can be expedited upon request.
4. Can home collection be arranged for this test?
Yes, for whole blood samples only. Our VIP Mobile Phlebotomy service is available daily from 8 AM to 11 PM. Specimens are transported at 18–22°C. Bone marrow collection requires a hospital setting and must be arranged separately. Contact us for scheduling.
UAE Regulatory & Data Privacy Adherence
Data Protection: All patient data is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
Accreditations: ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) with DHA facility license number 1143.
Corporate Branding: DNA Labs UAE · Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | Immunophenotyping by Flow Cytometry: Kappa and Lambda Light Chains |
| Price (AED) | 850 AED |
| Turnaround Time | Same‑day (sample by 9 AM) |
| Sample Type / Matrix | Whole blood (EDTA & Sodium Heparin) or bone marrow (Sodium Heparin) |
| Methodology Used | Fluorescent Flow Cytometry (LC‑MS/MS validated) |
| ICD-10-CM Code | D47.2 (Monoclonal gammopathy) |
| LOINC Code | 58438-6 (Immunophenotyping of B cells by flow cytometry, blood) |
| DHA Facility License & Laboratory Address | License 1143 · Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE · DNA Labs UAE |
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