Test Price
550 AED✅ Home Collection Available
Immunophenotyping by Flow Cytometry (CD123) Test in Dubai, UAE | 550 AED
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity via ISO 9001:2015 accredited processing with EuroFlow multicolor flow cytometry.
- Collection Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily 8 AM to 11 PM for peripheral blood specimens.
- Post-Test Guidance: Telephonic result interpretation provided by a DHA-licensed specialist diagnostic radiologist.
- Insurance & Billing: Direct billing verification via WhatsApp at +971 54 548 8731.
- Report Turnaround: Same-day electronic report delivery when sample is received by 9 AM.
Test Overview & Methodology
The CD123 immunophenotyping assay employs multicolor flow cytometry to detect the interleukin-3 receptor alpha chain (CD123) on hematopoietic cells. This analysis is essential for diagnosing acute leukemias, blastic plasmacytoid dendritic cell neoplasm (BPDCN), and myelodysplastic syndromes. The EuroFlow standardized panel enables precise quantification of CD123 expression intensity and percentage, providing critical data for disease classification and targeted therapy selection.
| Feature | DNA Labs UAE CD123 Test | Standard Alternative |
|---|---|---|
| Methodology | EuroFlow multicolor flow cytometry with dedicated CD123 monoclonal antibody panel on BD FACSCanto II | Basic 4-color flow cytometry with limited clone selection |
| Diagnostic Sensitivity | 99.9% per ISO 9001:2015 accreditation | ~95% with inter-lab variability |
| Turnaround Time | Same-day (sample received by 9 AM) | 2–3 business days |
| Specimen Transport | Active cold-chain maintained at 18–22°C with continuous temperature logging | Ambient transport with potential processing delays |
Specimen Requirements: Option 1 — 3 mL whole blood in lavender top (EDTA) tube plus 3 mL whole blood in green top (sodium heparin) tube. Option 2 — 2 mL bone marrow in green top (sodium heparin) tube. Transport immediately at 18–22°C; do not refrigerate or freeze. Include collection time, date, and clinical history on the test request form.
Physician Insight & Safety Protocols
"Interpreting CD123 expression patterns requires integration with peripheral blood morphology, bone marrow histology, and complete immunophenotypic profiles. This assay provides high-specificity data for differentiating myeloid neoplasms, but results must always be correlated with clinical presentation. Patients are encouraged to discuss findings with their referring physician in the context of their full diagnostic workup." — Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Patient Safety Exclusion Criteria
- Active severe bleeding disorder or therapeutic anticoagulation that cannot be temporarily paused for bone marrow aspiration.
- Known anaphylaxis to heparin or latex where alternative collection devices are unavailable.
- Inability to provide informed consent; for minors, guardian consent is required per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Emergency Indicators: If after sample collection you experience heavy bleeding, syncope, rapid local swelling, or dyspnea, seek immediate emergency care or call 998.
Clinical Advisory
This immunophenotyping test is a complement to comprehensive clinical evaluation, not a substitute. Do not discontinue or alter prescribed medications without consulting your treating physician. Results should be interpreted alongside complete blood counts, peripheral smear, and bone marrow histology when applicable.
Patient FAQ & Clinical Guidance
1. What is CD123 immunophenotyping and why is it used?
CD123 immunophenotyping by flow cytometry identifies the interleukin-3 receptor alpha chain on abnormal hematopoietic cells. This marker is overexpressed in several hematologic malignancies including acute myeloid leukemia, blastic plasmacytoid dendritic cell neoplasm, and hairy cell leukemia. The test enables precise disease classification and guides targeted therapy decisions such as anti-CD123 monoclonal antibody treatments.
2. How should I prepare for the CD123 flow cytometry test?
No fasting is required. Inform the phlebotomist of all current medications including chemotherapy, immunotherapy, and colony-stimulating factors. Provide a brief clinical history detailing any suspected or known diagnosis, recent treatments, and relevant laboratory findings to ensure accurate result correlation.
3. When will I receive my results and how are they interpreted?
Results are delivered electronically on the same day when the sample is received by 9 AM. The report includes the percentage and mean fluorescence intensity of CD123-positive cells, gating strategy details, and an integrated interpretation correlating findings with other immunophenotypic markers and clinical context.
4. Can this test be performed at home or does it require a hospital visit?
For peripheral whole blood collection, our VIP mobile phlebotomy service is available daily from 8 AM to 11 PM with temperature-controlled cold-chain transport. If bone marrow aspiration is required, the procedure must be performed in an accredited hospital setting by a qualified clinician.
5. What is the difference between CD123 and other leukemia markers?
CD123 is specifically overexpressed in certain leukemia subtypes and BPDCN, whereas markers like CD33, CD34, and CD117 are expressed across a broader range of myeloid neoplasms. The combined panel of markers in EuroFlow analysis provides a comprehensive immunophenotypic profile for accurate subclassification and prognostic assessment.
UAE Regulatory & Data Privacy Adherence
This clinical testing service operates in full compliance with UAE federal data protection and healthcare privacy frameworks. All patient data is processed and stored in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE holds ISO 9001:2015 certification (INT/EGQ/2509DA/3139) and maintains DHA Facility License No. 1143 for diagnostic laboratory services in Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | Immunophenotyping by Flow Cytometry (CD123) |
| Price (AED) | 550 |
| Turnaround Time | Same-day (sample received by 9 AM) |
| Sample Type / Matrix | Peripheral whole blood (EDTA + sodium heparin) / Bone marrow (sodium heparin) |
| Methodology Used | EuroFlow multicolor flow cytometry with CD123 monoclonal antibody panel (BD FACSCanto II) |
| ICD-10-CM Code | C95.90 |
| LOINC Code | 81183-9 |
| DHA Facility License & Address | License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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