Test Price
450 AED✅ Home Collection Available
IgG Heavy Chain Cytoplasmic Immunophenotyping by Flow Cytometry in UAE | 450 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
- Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This high-precision assay detects cytoplasmic expression of IgG heavy chains in B‑cells and plasma cells by multiparametric flow cytometry, essential for classifying mature B‑cell neoplasms such as multiple myeloma and lymphoplasmacytic lymphoma. The test employs fluorescent antibody paneling with cytoplasmic permeabilization and volumetric cell analysis to provide definitive immunophenotypic characterization.
| Feature | Our Test (UAE) | Closest Alternative |
|---|---|---|
| Precision / Method | Multiparametric Flow Cytometry (FACSCanto II) with cytoplasmic staining, fluorescent antibodies, and iso‑volumetric analysis | Standard 4‑color flow cytometry without cytoplasmic permeabilization |
| Diagnostic Speed | Same‑day report (sample by 9 AM) | Next‑day or 48‑hour turnaround |
| Sample Flexibility | Accepts whole blood (EDTA or heparin) and bone marrow aspirate; immediate ambient transport at 18–22°C | Requires dedicated sodium heparin tube only; stricter cold‑chain needs |
Physician Insight & Safety Protocols
A Note from Mr. Prabhakar Reddy Kalathoor (Specialist Diagnostic Radiology, DHA Registration ID: 61713011)
Cytoplasmic IgG detection by flow cytometry must be interpreted alongside morphology, clinical history, and other phenotypic markers. No single test is diagnostic in isolation, and any result requires correlation with the treating oncologist or hematologist to avoid misclassification of indolent versus aggressive disease. The combination of surface and cytoplasmic immunophenotyping provides a comprehensive profile that guides targeted therapy decisions in plasma cell dyscrasias.
Advisory: Medication Continuation
⚠️ Do not discontinue prescribed medications without consulting your treating physician. Temporary adjustments may be required for certain chemotherapeutic agents; your oncologist will provide specific guidance.
Exclusion Criteria & Emergency Red Flags
- Specimen Rejection: Clotted samples, refrigerated or frozen specimens, tubes without exact lavender (EDTA) or green (sodium heparin) top, bone marrow volume less than 1 mL.
- Patient Exclusion: Active severe infection with leukocyte left shift; recent chemotherapy within 7 days that may compromise cell viability.
- Red Flags for Immediate ER: Dyspnea, uncontrolled bleeding, loss of consciousness, or sudden severe pain after sample collection – seek emergency care or call 998.
- Minors: Parental or legal guardian consent required as per Federal Decree-Law No. 4 of 2016 on Medical Liability; collection for children supervised by a pediatric phlebotomist within the hospital setting.
Patient FAQ & Clinical Guidance
1. Why do I need this test instead of a bone marrow biopsy alone?
This test determines whether abnormal B‑cells or plasma cells are producing IgG heavy chain in the cytoplasm, which refines the diagnosis of disorders like multiple myeloma or Waldenström macroglobulinemia and guides targeted therapy. A stand‑alone biopsy cannot always resolve the immunophenotypic profile required for precise subclassification and prognostic stratification.
2. What does a positive cytoplasmic IgG result mean for my treatment plan?
A positive cytoplasmic IgG heavy chain indicates a clonal plasma cell or lymphoplasmacytic population, which typically correlates with diseases such as IgG multiple myeloma or lymphoplasmacytic lymphoma. This finding may prompt your oncologist to initiate or adjust chemotherapy, immunotherapy, or autologous transplant strategies based on the complete clinical picture and additional marker analysis.
3. Can I continue taking prescribed medications before sample collection?
Never stop prescribed medications without your doctor's approval. Provide a brief clinical history of your current treatment regimen; most drugs do not interfere with this assay. Your physician will advise on any temporary adjustments if needed to ensure optimal cell viability and accurate immunophenotyping results.
UAE Regulatory & Data Privacy Adherence
🛡️ DHA‑Compliant & Ministry of Health Approved (License 1143) · ISO 9001:2015 Certified
All patient data is processed in strict accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Your personal health information is encrypted, access‑controlled, and never shared without explicit written consent.
Clinical & Logistical Metadata
| Test Name | IgG Heavy Chain Cytoplasmic Immunophenotyping by Flow Cytometry |
| Price (AED) | 450 AED |
| Turnaround Time | Same day (sample received by 9 AM) |
| Sample Type / Matrix | Bone marrow aspirate (2 mL in green top sodium heparin) or peripheral whole blood (3 mL lavender top EDTA + 3 mL green top sodium heparin); hospital extraction only |
| Methodology Used | Multiparametric flow cytometry (FACSCanto II) with cytoplasmic permeabilization, fluorescent antibody panel, and isovolumetric analysis |
| ICD-10-CM Code | C90.0, C90.1, D47.2, C83.0 |
| LOINC Code | 43142-9 |
| DHA Facility License & Laboratory Address | License 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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