Test Price
2,800 AED✅ Home Collection Available
MYLK2 Gene Sequencing for Hypertrophic Cardiomyopathy in UAE | 2,800 AED | DHA Licensed Genetic Analysis
Executive Summary & Core Metrics
This advanced genetic sequencing test detects pathogenic variants in the MYLK2 gene associated with hypertrophic cardiomyopathy, enabling precise risk stratification and informed family screening. The analysis is performed under ISO-accredited protocols at DNA Labs UAE, governed by the Dubai Healthcare City Authority and DHA Facility License 1143.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Next Generation Sequencing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation from a Consultant Medical Geneticist.
- Insurance & Billing: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The MYLK2 gene test identifies single-nucleotide variants and small insertions or deletions across the entire coding region and splice-site boundaries. Pathogenic alterations in MYLK2 are linked to hypertrophic cardiomyopathy with midventricular involvement and digenic inheritance patterns. This analysis provides robust data for clinical decision-making, risk stratification, and cascade screening of at-risk relatives.
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Precision | 99.9% Analytical Sensitivity for MYLK2 full gene | ~99% for single exon, may miss deep intronic variants |
| Method | Next Generation Sequencing (NGS) – complete coding & splice sites | Capillary sequencing of selected regions |
| Speed (TAT) | 3-4 weeks | 6-8 weeks |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I emphasize that MYLK2 sequencing must be interpreted within the full clinical context — including echocardiographic findings, family pedigree analysis, and electrocardiographic data. A genetic variant alone does not establish a diagnosis; it is one component of a comprehensive cardiovascular risk assessment. Your referring physician will correlate all results before clinical action.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication & Clinical Advisory
Essential Safety Information
Never discontinue or adjust prescribed cardiac medications — including beta-blockers, calcium channel blockers, or antiarrhythmics — without direct consultation with your treating physician. This genetic test does not replace clinical monitoring or imaging surveillance for hypertrophic cardiomyopathy.
- Emergency Red Flags: Sudden chest pain, syncope (fainting), severe shortness of breath, or palpitations require immediate emergency care.
- Pregnancy: Not a contraindication for genetic testing, but requires prior discussion with your obstetrician and cardiologist.
Exclusion Criteria
- Individuals without clinical suspicion of hypertrophic cardiomyopathy based on cardiology evaluation.
- Minors unless accompanied by a legal guardian and compliant with UAE pediatric consent regulations.
- Patients with prior cardiac transplantation where native DNA is no longer circulating.
Patient FAQ & Clinical Guidance
1. What is the MYLK2 gene test used for?
This test identifies disease-causing DNA variants in the MYLK2 gene, which are associated with hypertrophic cardiomyopathy — specifically the midventricular form with potential digenic inheritance. Results aid in diagnosis, risk stratification, and family screening decisions.
2. How is the sample collected?
A trained phlebotomist collects a peripheral blood sample through our VIP Mobile Phlebotomy service, following strict temperature-controlled cold-chain protocols. Home collection is available daily from 8 AM to 11 PM. Alternatively, you may visit our Dubai Healthcare City facility for in-clinic blood draw.
3. What is the turnaround time for results?
Results are delivered within 3 to 4 weeks from sample receipt at our CAP-accredited laboratory. A comprehensive clinical interpretation report, including variant classification per ACMG guidelines, is provided.
4. Will my insurance cover this test?
Coverage varies by insurer and policy. Contact our billing team via WhatsApp at +971 54 548 8731 for direct verification and pre-authorization assistance.
5. Do I need a doctor referral to proceed?
Yes, a referral from a cardiologist or genetic specialist is required. Our team coordinates with your referring physician to ensure appropriate test selection and result interpretation.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates in full compliance with the UAE federal legal framework governing genetic data and health information. All patient data, including genetic sequencing results, are processed and stored under the protections of Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic information remains confidential and is used solely for the purpose of diagnostic interpretation and clinical guidance as authorized by you and your referring physician.
DHA Facility License: 1143 | Corporate Lab: DNA Labs UAE | Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
Clinical & Logistical Metadata
| Test Name | MYLK2 Gene Sequencing for Hypertrophic Cardiomyopathy |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks from sample receipt |
| Sample Type / Matrix | Peripheral whole blood (5–10 mL in EDTA tube) — VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM to 11 PM |
| Methodology Used | Next Generation Sequencing (NGS) — full coding region and splice-site analysis |
| ICD-10-CM Code | I42.1 (Obstructive hypertrophic cardiomyopathy) |
| LOINC Code | 82897-8 (MYLK2 gene mutation analysis) |
| DHA Facility License & Laboratory Address | DHA License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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