Test Price
750 AED✅ Home Collection Available
Human Papillomavirus (HPV) 16 & 18 RNA Detection, Qualitative Test in UAE | 750 AED
Executive Summary & Core Metrics
Executive Summary: This RNA-based assay detects active E6/E7 mRNA of high-risk HPV 16 & 18, providing definitive clinical specificity for transforming infections that may progress to cervical cancer. The qualitative RT-qPCR result directly guides triage to colposcopy, reducing unnecessary procedures while capturing high-grade dysplasia with >97% sensitivity for CIN2+. Includes 24/7 VIP mobile home collection, secure ISO 9001:2015 certified processing, and direct physician result interpretation.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 certified laboratory (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital-grade home collection for cervical swab via temperature-controlled chain and VIP mobile service (8 AM – 11 PM daily).
- Clinical Guidance: Telephonic post-test result interpretation by our senior clinical team, ensuring immediate correlation with cytology and patient history.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731 – submit your policy for instant confirmation.
Test Overview & Methodology
The HPV 16 & 18 RNA Detection Test identifies messenger RNA of the E6/E7 oncogenes using Reverse Transcription Real-Time PCR (RT-qPCR), offering superior specificity for active, clinically significant infections compared to conventional DNA-based methods. This qualitative assay distinguishes transforming infections that drive cervical carcinogenesis from transient viral shedding, enabling precise triage of patients with abnormal cytology.
| Feature | Our HPV RNA Test | Closest Alternative (HPV DNA) |
|---|---|---|
| Methodology | Reverse Transcription Real-Time PCR (RT-qPCR) | Hybrid Capture / DNA PCR |
| Clinical Sensitivity (CIN2+) | >97% | ~94% |
| Specificity for Active Infection | Near 100% (detects oncogene expression) | Lower – may detect cleared transient infections |
| Turnaround Time | 24 – 36 hours | 5 – 7 days |
| Sample Type | Cervical Swab (self-collected or provider-collected) | Cervical Swab |
| UAE Regulatory & Accreditation | DHA Licensed, ISO 9001:2015, UAE PDPL Compliant | Varies |
Physician Insight & Safety Protocols
Mr. Prabhakar Reddy Kalathoor (Specialist Diagnostic Radiology, DHA Registration ID: 61713011) notes: “An HPV 16/18 RNA positive result is a strong biomarker for high-grade dysplasia and requires immediate colposcopy referral. A negative result, however, does not entirely rule out cervical neoplasia—other high‑risk types or rare endocervical lesions may still exist. Clinical correlation with cytology and patient history remains paramount for every individual.”
Pre-Test Advisory
⚠ Specimen Quality Advisory
Accurate RNA detection depends on adequate cellular sampling from the cervical transformation zone. Avoid sexual intercourse, douching, vaginal medications, and tampon use for 48 hours prior to collection. Heavy menstrual bleeding may dilute cellular content; rescheduling is recommended. The test does not replace regular gynaecological surveillance or Pap smear screening.
Exclusion Criteria & Emergency Signals
- Exclusion: Active heavy menstrual bleeding – reschedule until flow is light or finished.
- Exclusion: Recent (<48 hours) vaginal intercourse, douching, or use of vaginal creams or medicated pessaries.
- Exclusion: Known allergy to medical latex (alternative non-latex kit available on request).
- Emergency Red Flag: Severe pelvic pain, uncontrolled vaginal bleeding, fever >38.5°C, or signs of systemic infection following sample collection – seek immediate medical attention.
Patient FAQ & Clinical Guidance
1. What is the difference between HPV RNA and HPV DNA testing?
HPV RNA detects E6/E7 mRNA, signaling active infection and higher specificity for cervical precancer than DNA.
This RNA-based test identifies the presence of messenger RNA from HPV types 16 and 18, the most oncogenic strains. Unlike DNA tests, which may detect transient or cleared infections, RNA positivity indicates active viral gene expression and is strongly linked to CIN2+ lesions. It is particularly useful for triage of women with ASC‑US cytology.
2. Is the cervical swab for this test painful?
The collection is quick and minimally uncomfortable, similar to a routine Pap smear, with no lasting pain.
Our trained clinical team uses a soft cervical brush that gently reaches the transformation zone. Most patients report only a mild sensation of pressure or mild cramping lasting a few seconds. For anxious patients, a chaperone and detailed guidance are provided during home collection.
3. How should I prepare for this HPV RNA test?
Avoid sexual intercourse, douching, and vaginal medications for 48 hours before the test to ensure accurate results.
Proper preparation prevents interference with the cervical specimen. Do not use spermicidal foams, jellies, or tampons. Schedule the test when you are not menstruating heavily. Bring your clinical history and a signed consent form, which will be provided via WhatsApp or at the time of home collection.
4. How are results delivered and interpreted?
Results are reported within 24–36 hours with a clear qualitative result (detected or not detected) and a telephonic physician review.
You will receive a secure digital report with interpretative comments. Our senior clinical team calls to explain the result in the context of your gynaecological history and to coordinate any indicated follow-up, such as colposcopy referral, if positive.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance: All clinical data and test results are processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent for sample collection and molecular analysis adheres to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Laboratory Licensing: This test is performed under DHA Facility License Number 1143 at DNA Labs UAE, located at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. International accreditation: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). Teleconsultation and result interpretation are supplementary to standard medical care.
Clinical & Logistical Metadata
| Test Name | Human Papillomavirus (HPV) 16 & 18 RNA Detection, Qualitative |
| Price (AED) | 750 AED |
| Turnaround Time | 24 – 36 hours |
| Sample Type / Matrix | Cervical Swab (endocervical / ectocervical) |
| Methodology Used | Reverse Transcription Real-Time PCR (RT-qPCR) |
| ICD-10-CM Code | Z11.51, R87.810, Z15.89 |
| LOINC Code | 80380-7 |
| DHA Facility License & Laboratory Address | License #1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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