Test Price
1,500 AED✅ Home Collection Available
HLA Celiac Disease (DQ2/DQ8) Haplotype Association Test in UAE
1500 AED — Genetic Risk Stratification for Gluten Intolerance
Executive Summary & Core Metrics
This DNA-based PCR assay detects the high-risk genetic markers HLA-DQ2 and HLA-DQ8 with 99.9% diagnostic sensitivity via ISO-accredited processing. The test provides lifelong risk stratification for celiac disease and supports differential diagnosis of malabsorption syndromes. A telephonic post-test clinical guidance session is included to help interpret results in the context of serology, histology, and symptoms.
Test Overview & Methodology
The HLA Celiac Disease Haplotype Test identifies the high-risk genetic markers HLA-DQ2 and HLA-DQ8, which are present in over 95% of individuals with celiac disease. This DNA-based PCR assay stratifies lifelong gluten intolerance risk and supports differential diagnosis of malabsorption syndromes. The methodology uses Sequence-Specific Primer PCR (SSP-PCR), delivering a predictive negative value that virtually rules out celiac disease when both markers are absent.
| Feature | Our HLA Haplotype Test | Serology (tTG-IgA) |
|---|---|---|
| Precision | 99.9% predictive negative value – virtually rules out celiac disease if absent | High sensitivity but may miss early or IgA-deficient cases |
| Method | Sequence-Specific Primer PCR (SSP-PCR) | Enzyme-linked immunoassay (ELISA) |
| Turnaround | 7 Working Days | 1–3 Days |
| Clinical Utility | Lifelong genetic risk stratification; aids in family screening | Reflects active immune response; requires gluten challenge |
Physician Insight & Safety Protocols
“A positive HLA-DQ2/DQ8 result indicates genetic susceptibility, not active disease. I always emphasize that this test must be interpreted alongside serology, histological findings, and clinical symptoms. Never start a gluten-free diet based on genetics alone – consult your gastroenterologist for a comprehensive evaluation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠ Important Clinical Advisory
Do not discontinue any prescribed medication, alter your diet, or begin a gluten-free regimen without first consulting your managing physician. This genetic test is a risk assessment tool and must not replace a full clinical workup including serology and duodenal biopsy if indicated.
Patient Safety: Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Active severe infection, recent blood transfusion (within 3 months), or known hematological malignancy may affect sample integrity and test accuracy.
- Emergency Red Flags: If you experience severe abdominal pain, bloody stools, unexplained weight loss, or signs of intestinal obstruction, seek immediate medical attention – do not wait for test results.
- Age & Consent: Minors (under 18 years) require parental or legal guardian consent as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Data Privacy: Your genetic data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and processed only within licensed facilities (DHA License No. 1143).
Patient FAQ & Clinical Guidance
1. What does a positive HLA-DQ2/DQ8 result mean for my health?
A positive result indicates you carry one or both of the high-risk genetic markers associated with celiac disease. This means you have a genetic susceptibility, but it does not confirm active disease. Clinical correlation with serology (tTG-IgA, EMA), duodenal biopsy, and symptoms is always required for a definitive diagnosis. A negative result virtually rules out celiac disease and has a high predictive negative value.
2. How should I prepare for the test, and can I do it from home?
No fasting, special diet, or medication adjustment is needed prior to sample collection. Our DHA-licensed mobile phlebotomy team can collect the peripheral whole blood sample at your residence using an ISO-certified temperature-controlled cold-chain protocol. Home collection is available daily from 8 AM to 11 PM. Simply contact us via WhatsApp at +971 54 548 8731 to schedule an appointment.
3. Will insurance cover the HLA typing, and how fast will I receive results?
Most UAE health insurance plans cover genetic testing for celiac disease risk stratification, subject to policy terms and pre-approval. We offer direct billing verification and can check your coverage instantly via WhatsApp. Test results with a detailed clinical interpretation are delivered within 7 working days from sample collection at the laboratory.
UAE Regulatory & Data Privacy Adherence
- Licensed by DHA under Facility License Number: 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
- Corporate Lab Branding: DNA Labs UAE — ISO 9001:2015 Certified (Certificate No: INT/EGQ/2509DA/3139).
- Genetic data processing complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Home collection service available daily 8 AM – 11 PM. WhatsApp support: +971 54 548 8731.
Clinical & Logistical Metadata
| Test Name | HLA Celiac Disease (DQ2/DQ8) Haplotype Association Test |
| Price (AED) | 1500 AED |
| Turnaround Time | 7 Working Days |
| Sample Type / Matrix | Peripheral Whole Blood – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM – 11 PM) |
| Methodology Used | Sequence-Specific Primer PCR (SSP-PCR) |
| ICD-10-CM Code | Z13.82, K90.0 |
| LOINC Code | 53380-0, 53381-8 |
| DHA Facility License & Address | License No: 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE — DNA Labs UAE |
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