Test Price
2,800 AEDโ Home Collection Available
HLA DNA Typing for Bone Marrow Transplant (10 Antigens) PCR Test in UAE
Executive Summary & Core Metrics
This high-resolution HLA DNA typing test evaluates 10 critical Class I & II antigens (HLA-A, B, C, DR, DQ) using SSP-PCR (Sequence Specific Primers) technology, offering 99.9% diagnostic sensitivity. The test is essential for matching bone marrow transplant donors and recipients, drastically reducing graft-versus-host disease risk. Price: 2,800 AED. Turnaround time: 10โ12 working days. VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM. Direct billing verification via WhatsApp: +971 54 548 8731.
Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AMโ11 PM).
Clinical Guidance: Post-test telephonic consultation with a Consultant Medical Genetics.
Insurance: Direct Billing Verification available via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This molecular test employs SSP-PCR (Sequence Specific Primers) to amplify and identify specific HLA gene alleles at high resolution. Unlike conventional serological typing (which only detects antigens at the protein level), SSP-PCR discriminates individual nucleotide differences, providing unambiguous results critical for unrelated donor matching.
| Feature | Our ISO-Accredited SSP-PCR Test | Conventional Serological Typing |
|---|---|---|
| Precision | High-resolution DNA-level allele discrimination | Low-resolution protein-based (antigen-level) only |
| Methodology | SSP-PCR (Sequence Specific Primers) + PCR Amplification | Complement-dependent microcytotoxicity |
| Turnaround | 10โ12 working days | 5โ7 days (but with ambiguous results) |
| Clinical Utility | Gold standard for unrelated donor matching | Preliminary screening only |
Physician Insight & Safety Protocols
โInterpreting HLA typing for bone marrow transplant requires clinical correlation; a perfect match does not guarantee transplant success, and close monitoring remains essential. I advise all patients to discuss results with their hematologist to understand graft-versus-host disease risks. This high-resolution SSP-PCR test is the recommended approach for unrelated donor selection.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed medication without consulting your doctor. This test does not replace any ongoing treatment.
Safety Exclusion Criteria & Emergency Red Flags
- Active systemic infection or febrile illness at the time of sample collection; reschedule after recovery.
- Severe coagulopathy or platelet count below 20,000/ยตL unless medically cleared for venipuncture.
- Known allergy to antiseptics used during phlebotomy โ discuss alternatives with the collection team.
- ER Red Flags post-procedure: Persistent bleeding lasting more than 20 minutes, expanding hematoma, signs of anaphylaxis (facial swelling, difficulty breathing) โ seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is the HLA 10-antigen PCR test, and why is it essential before a bone marrow transplant?
Answer: The test analyzes DNA of 10 HLA antigens (Class I: A, B, C; Class II: DR, DQ) using SSP-PCR to identify the best donor-recipient match, drastically reducing failure rates from graft-versus-host disease. Without such high-resolution matching, the risk of severe rejection increases significantly, especially in unrelated donors.
2. How is the sample collected, and can I choose home phlebotomy in the UAE?
Answer: A trained phlebotomist collects 4 mL whole blood in a lavender-top EDTA tube or 6 mL in a yellow-top ACD tube during a home visit from 8 AM to 11 PM, with temperature-controlled cold-chain transport that never freezes the sample. You can book via WhatsApp +971 54 548 8731, and direct billing verification is available.
3. What do the UAE regulations say about HLA testing for minors?
Answer: Under the UAE Personal Data Protection Law (PDPL) and Federal Decree-Law No. 4 of 2016 on Medical Liability, HLA testing on individuals below 18 years requires explicit parental or guardian consent. All results are protected under health information confidentiality standards as per Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
4. Is any special preparation required before the blood draw?
Answer: No special preparation (e.g., fasting) is required. Continue all medications as prescribed. The sample must be collected in a lavender-top EDTA tube (4 mL) or yellow-top ACD tube (6 mL) and shipped refrigerated. Never freeze the specimen.
UAE Regulatory & Data Privacy Adherence
Compliance Framework: This service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability. All patient data is encrypted and handled under ISO 9001:2015 certified processes. The laboratory is licensed by the Dubai Health Authority (DHA) under Facility License Number 1143.
Clinical & Logistical Metadata
| Test Name | HLA DNA Typing for Bone Marrow Transplant (10 Antigens) PCR |
| Price (AED) | 2,800 AED |
| Turnaround Time | 10โ12 working days |
| Sample Type / Matrix | Peripheral whole blood (4 mL lavender-top EDTA or 6 mL yellow-top ACD tube) |
| Methodology Used | SSP-PCR (Sequence Specific Primers) + PCR Amplification |
| ICD-10-CM Code | Z94.81 (Bone marrow transplant status), Z52.0 (Bone marrow donor), Z01.89 (Encounter for other specified special examinations) |
| LOINC Code | 10320-2 (HLA-A,B,C,DR,DQ panel) |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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