Test Price
750 AEDโ Home Collection Available
HLA-B27 Flow Cytometry Test in UAE | 750 AED | DHA-Approved
Executive Summary & Core Metrics
Executive Summary
This test delivers 99.9% diagnostic sensitivity for HLA-B27 antigen detection, processed in an ISO 9001:2015 certified laboratory using standardized flow cytometric immunophenotyping. We offer paid hospital-grade home collection via ISO certified cold-chain logistics and VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection services, available daily from 8 AM to 11 PM. Telephonic post-test clinical guidance for result interpretation is included. Direct insurance billing verification is available via WhatsApp at +971 54 548 8731. DNA Labs UAE is your trusted provider for this precise immunophenotyping assay.
Test Overview & Methodology
HLA-B27 is a protein marker strongly associated with ankylosing spondylitis and other spondyloarthropathies; this flow cytometry test identifies its presence on white blood cells with high precision. The methodology uses fluorescently labeled antibodies and laser-based detection to quantify antigen expression on leukocytes, providing a reliable binary result (positive or negative) that aids rheumatologic diagnosis.
| Feature | Our Test (Flow Cytometry) | Closest Alternative (PCRโbased HLA-B27) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity / reliable antigen detection | High sensitivity but may miss antigen-loss variants |
| Methodology | Flow Cytometry (Immunophenotyping by Fluorescent Antibodies) | PCR/SSP genotyping (DNA-based) |
| Turnaround Time | 1 week | 5โ7 working days |
Physician Insight & Safety Protocols
"This test is a valuable tool in the diagnostic workup for inflammatory back pain. However, diagnosis requires integration with clinical evaluation and MRI findings. A positive HLA-B27 increases spondyloarthritis risk, but it is never diagnostic in isolation. Always consult your rheumatologist before making treatment decisions." โ Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132
Advisory Notes
Medication Safety
Do not discontinue any prescribed medication without consulting your doctor. Results from this test are intended to support, not replace, your physician's clinical judgment.
Exclusion Criteria & ER Red Flags
Important Contraindications
- Patients with active severe systemic infection or hemodynamic instability should defer the test (unless medically urgent).
- Known allergy to antiseptic used for phlebotomy โ inform collection team beforehand.
- ER Red Flag: Sudden severe back pain accompanied by leg weakness, numbness around the saddle area, loss of bladder or bowel control, or high fever โ seek emergency care immediately.
- ER Red Flag: New-onset joint swelling with skin rashes and recurrent eye inflammation (possible systemic autoimmune flare) โ contact your rheumatologist or visit ER.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of HLA-B27 testing?
Flow cytometry detects HLA-B27 antigen on leukocytes for diagnosing ankylosing spondylitis and spondyloarthropathies accurately. The result must be correlated with clinical history, inflammatory back pain pattern, and imaging (Xโray/MRI) because a positive result alone does not confirm disease, nor does a negative rule it out entirely.
2. Is fasting required before the test?
No, fasting is not required for the HLA-B27 flow cytometry test. You may eat and drink normally. The test can be performed at any time of day without special preparation. Continue your regular medications unless otherwise advised by your physician.
3. How should I interpret a positive HLA-B27 result?
Positive HLA-B27 increases spondyloarthritis risk, but diagnosis requires careful clinician evaluation, imaging, and symptom review. A positive result is present in approximately 90% of ankylosing spondylitis patients, yet also occurs in 6-8% of healthy individuals; therefore, it is never diagnostic in isolation and must be interpreted by a rheumatologist in the full clinical context.
UAE Regulatory & Data Privacy Adherence
Data Protection and Compliance
All patient data is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety follows Federal Decree-Law No. 4 of 2016 on Medical Liability. The laboratory is ISO 9001:2015 certified (INT/EGQ/2509DA/3139) and operates under DHA Facility License No. 1143. Patient confidentiality and test result security are paramount.
Clinical & Logistical Metadata
| Test Name | HLA-B27 by Flow Cytometry |
| Price (AED) | 750 AED |
| Turnaround Time | 7 Days (1 Week) |
| Sample Type / Matrix | Whole Blood (Peripheral Blood) โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available Daily from 8 AM to 11 PM |
| Methodology Used | Flow Cytometry (Immunophenotyping) |
| ICD-10-CM Code | M45.9 |
| LOINC Code | 19992-0 |
| DHA Facility License & Laboratory Address | DHA License: 1143, DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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