Test Price
1,300 AED✅ Home Collection Available
HLA T and B Cell Flow Cytometry Crossmatch in UAE | 1300 AED | 2026 DHA Guidelines
تحليل التوافق النسيجي للخلايا التائية والبائية بطريقة التدفق الخلوي في الإمارات | 1300 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection. VIP Mobile Phlebotomy available.
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر معالجة معتمدة من الآيزو.
الخدمات اللوجستية المتميزة: خدمة سحب الدم المنزلي على مستوى المستشفيات عبر سلسلة تبريد معتمدة، وخدمة الفصد المتنقل لكبار الشخصيات.
الإرشاد السريري: استشارة هاتفية بعد الفحص لتفسير النتائج.
التأمين: التحقق المباشر من الفواتير عبر واتساب +971545488731.
What is the HLA T and B Cell Flow Cytometry Crossmatch?
This test uses advanced flow cytometry to detect donor-specific antibodies against recipient T and B lymphocytes, providing a critical compatibility check before solid organ transplantation. النتيجة الدقيقة تمنع رفض الطعم الحاد وتوجه قرارات زراعة الكلى.
It measures both IgG and IgM antibodies with single-cell sensitivity, far surpassing older complement-dependent cytotoxicity (CDC) methods.
| Feature | Our Test | Closest Alternative (CDC) |
|---|---|---|
| Methodology | 3-Color Fluorescent Flow Cytometry (FACS) | Complement-Dependent Cytotoxicity |
| Diagnostic Sensitivity | >99% (detects low-titer non-complement-fixing antibodies) | ~80% (misses weak/non-cytotoxic antibodies) |
| Turnaround Time | 10–12 working days | 5–7 days (lower informational value) |
| Specific Cell Identification | Separate T-cell & B-cell channel interpretation | No cell-type discrimination |
| Clinical Relevance | 2026 DHA/EFI guideline-aligned, virtual crossmatch capable | Historical use only, not recommended for high-risk patients |
Clinical Expert Commentary
“A positive flow crossmatch to donor B cells may indicate the presence of non-cytotoxic antibodies that still increase rejection risk. Correlate with single antigen bead assays and the patient’s complete immunological history. Never rely solely on crossmatch results; discuss all findings with your transplant team.”
— Dr. PRABHAKAR REDDY, DHA License 61713011
Medication Warning
Do not discontinue prescribed immunosuppressants, anticoagulants, or any other medication without consulting your doctor. The test result alone does not replace clinical decision-making.
Exclusion Criteria & Emergency Red Flags
- Sampling within 48 hours post-dialysis may yield false results; collect specimen preferably 48 hours after dialysis.
- Active systemic infection or recent vaccination (within 2 weeks) can transiently alter antibody profiles – reschedule if clinically safe.
- RED FLAG: If recipient develops acute graft dysfunction (oliguria, fever, graft tenderness) during testing wait period, go to the nearest emergency department immediately – do not wait for lab results.
- Missing mandatory documents (doctor’s prescription with stamp, one photograph each of recipient and donor, completed Solid Organ Transplant Consent Form 33) will delay processing; our team will contact you.
Frequently Asked Questions
1. Why is the T-cell and B-cell distinction important in this crossmatch?
The HLA flow crossmatch separately identifies T-cell IgG antibodies, which are strongly associated with acute rejection, and B-cell antibodies—including those against class II HLA—that may signal chronic antibody-mediated damage. يكشف فحص التوافق النسيجي بالتدفق الخلوي عن الأجسام المضادة الخاصة بالخلايا التائية IgG المرتبطة بالرفض الحاد، والأجسام المضادة للخلايا البائية التي تنبئ بالضرر المزمن المناعي.
2. Can I perform this at home, and how is the sample collected?
Yes, our DHA-licensed mobile phlebotomy team collects both recipient and donor blood samples in your home between 8 AM and 11 PM. Samples are transported at 18–22°C in validated cold-chain boxes to the ISO 9001:2015 lab immediately—never frozen, preserving lymphocyte viability. نعم، يقوم فريق الفصد المرخص من هيئة الصحة بدبي بسحب عينات الدم من المتلقي والمتبرع في المنزل بين 8 صباحاً و11 مساءً، ويتم نقلها فوراً ضمن سلسلة تبريد معتمدة للحفاظ على حيوية الخلايا.
3. What if my crossmatch is positive—does it mean I cannot receive a transplant?
A positive flow crossmatch indicates donor-specific antibodies but does not automatically exclude transplantation; your nephrologist may use desensitization protocols (e.g., plasmapheresis, IVIg) based on the antibody strength and specificity. Clinical correlation with the physician is mandatory. لا تعني نتيجة التوافق الإيجابية استحالة الزرع؛ فقد يلجأ طبيب الكلى إلى بروتوكولات إزالة التحسس مثل فصل البلازما والغلوبولين المناعي الوريدي حسب شدة الأجسام المضادة ونوعيتها.
This screening service is compliant with Federal Decree-Law No. 41 of 2024 (Art. 87), UAE CDS Law 2026 (Minors), and UAE PDPL. Laboratory accredited ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139), DHA Facility License 9834453. All data handled per UAE health data privacy regulations.
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