HLA T & B Cell Lymphocyte Crossmatch Test in UAE | 1,300 AED | DNA Labs UAE

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Hospital‑Grade Home Collection (8 AM‑11 PM) with ISO‑Certified Cold‑Chain Transport & VIP Mobile Phlebotomy.
Clinical Guidance: Telephonic Post‑Test Clinical Guidance for result interpretation by our clinical team.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The HLA T & B Cell Lymphocyte Crossmatch is a definitive immunological assay that detects pre‑formed donor‑specific antibodies (DSA) in solid organ transplantation. It directly assesses the risk of hyperacute rejection by mixing recipient serum with donor lymphocytes. This test is mandatory before kidney transplantation under UAE transplant protocols and is performed using the Complement-Dependent Cytotoxicity (CDC) method with DTT treatment to eliminate IgM interference, ensuring only clinically relevant IgG antibodies are evaluated.

Parameter	CDC-XM with DTT (Our Test)	Flow Cytometry Crossmatch (Alternative)
Precision	Gold‑standard for T‑cell antibodies; eliminates IgM interference via DTT	Higher sensitivity for B‑cell antibodies, but may detect non‑cytotoxic IgM
Clinical Specificity	Identifies complement‑fixing IgG antibodies; strong correlation with graft survival	Less specific in separating complement‑fixing from non‑fixing antibodies
Turnaround Time	10–12 working days	7–10 working days (often used as supplementary test)
Regulatory Acceptance	Mandated by DHA/MOHAP for all deceased & live donor transplant workups	Accepted only as a complementary assay, not a standalone decision tool

Physician Insight & Safety Protocols

“Based on my clinical experience managing transplant candidates, a positive crossmatch is a critical finding that requires correlation with donor‑specific antibody strength and the patient’s overall clinical urgency. We are committed to providing compassionate support and clear communication throughout your diagnostic journey. Please never discontinue or alter immunosuppressive medications without explicit guidance from your transplant team.”

— Dr. Ajay Singh, General Practitioner | DHA Registration ID: 36234132

⚠️ Medication Safety Advisory

Do not discontinue prescribed immunosuppressive medication, anticoagulants, or anti‑hypertensives before the test without consulting your doctor.

Exclusion Criteria & Emergency Red Flags

Test Exclusion: Recent blood transfusion (< 4 weeks), active systemic infection, or administration of IVIg/rituximab within 3 months (can interfere with assay).
ER Red Flags – Seek Immediate Medical Care: Sudden decrease in urine output, flank pain over the graft, fever > 38.5 °C, or severe dyspnea after transplant.
Paediatric Consent: Written informed consent from a legal guardian is mandatory for minors; all data handled per UAE PDPL.

Patient FAQ & Clinical Guidance

1. What exactly does the HLA T & B Cell Lymphocyte Crossmatch test detect?

This test directly measures whether recipient antibodies kill donor lymphocytes, predicting hyperacute rejection risk. The DTT treatment removes IgM, ensuring only clinically relevant IgG antibodies are evaluated.

2. Why does the test require photographs and Form 33?

These documents satisfy UAE regulatory requirements for traceability, donor‑recipient verification, and legal consent in solid organ transplantation as per Federal Law No. 2 of 2019.

3. How should I prepare for the blood draw?

Collect the sample preferably 48 hours after dialysis. Neither recipient nor donor must freeze the specimen—ship refrigerated only. Bring a valid Emirates ID, original doctor’s prescription, and the completed Solid Organ Transplant Consent Form (Form 33).

4. What sample volumes are required for this test?

Recipient: 1 ACD tube (6 mL whole blood) + 1 SST (3 mL serum). Donor: 2 ACD tubes (12 mL whole blood) per single crossmatch. Ship refrigerated; DO NOT FREEZE.

UAE Regulatory & Data Privacy Adherence

Our Regulatory Commitment

DNA Labs UAE strictly adheres to the legislative framework of the United Arab Emirates governing medical diagnostics and patient data protection. Our operations are fully compliant with:

Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): Ensuring the highest standards of data privacy and security for all patient health information.
Federal Law No. 2 of 2019: Concerning the Use of Information and Communication Technology in Health Fields, regulating the secure handling of electronic medical records and digital diagnostics.
Federal Decree-Law No. 4 of 2016 on Medical Liability: Governing clinical testing safety and informed patient consent protocols.
DHA Standards: Fully licensed by the Dubai Health Authority (DHA Facility License Number: 1143).

Clinical & Logistical Metadata

Test Name	HLA T & B Cell Lymphocyte Crossmatch
Price (AED)	1,300 AED
Turnaround Time	10–12 working days
Sample Type / Matrix	Whole Blood (ACD Tubes & SST)
Methodology Used	Complement-Dependent Cytotoxicity (CDC) with DTT Treatment
ICD-10-CM Code	Z94.0 (Kidney Transplant Status)
LOINC Code	4882-0 (HLA Crossmatch)
DHA Facility License & Lab Address	License No. 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE \| DNA Labs UAE