RB1 Gene Hereditary Retinoblastoma Genetic Test in UAE | 2,800 AED | DHA Licensed

Executive Summary & Core Metrics

✓ Accuracy Guarantee

99.9% Diagnostic Sensitivity via ISO Accredited Processing

✓ Premium Logistics

VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM)

✓ Clinical Guidance & Insurance

Telephonic Post-Test Clinical Guidance in Result Interpretation. Direct Billing Verification via WhatsApp +971 54 548 8731

Test Overview & Methodology

The RB1 gene NGS test sequences the entire coding region and exon-intron boundaries to detect germline mutations causing hereditary retinoblastoma, a rare childhood eye cancer. This high-resolution analysis enables early intervention, family risk stratification, and informed reproductive choices.

Feature	Our RB1 NGS Test	Standard Single-Gene PCR/MLPA
Precision	99.9% diagnostic sensitivity (full coding + exon-intron boundaries)	~85% sensitivity (misses deep intronic variants)
Method	Next-Generation Sequencing (Illumina™ platform, 500x coverage)	Sanger sequencing or MLPA (limited scope)
Turnaround Time	3–4 Weeks	4–6 Weeks

Physician Insight & Safety Protocols

“As a Consultant Medical Genetics, I emphasize that a germline RB1 mutation indicates a hereditary predisposition, not an active cancer diagnosis. Lifelong ophthalmologic surveillance and genetic counselling are essential to translate this genetic information into clinical action. Never base treatment decisions solely on this test; always correlate with clinical and imaging findings.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403)

⚠ Medication Advisory

Do not discontinue any prescribed medication without prior consultation with your treating physician. This genetic test does not replace ongoing oncologic or ophthalmologic care.

⛔ Exclusion Criteria & Emergency Red Flags

Not indicated as a stand-alone screening tool in asymptomatic individuals without family history or clinical suspicion of retinoblastoma.
For minors, genetic testing requires explicit parental/guardian consent in compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patients with active bleeding disorders or on anticoagulants must inform the phlebotomist before sample collection.
Seek immediate medical attention if the child develops leukocoria (white pupil), strabismus (crossed eyes), sudden vision loss, or eye redness.

Patient FAQ & Clinical Guidance

1. What does a positive RB1 mutation result mean for my child?

A positive result confirms a hereditary predisposition to retinoblastoma, requiring lifelong ocular surveillance every 2–4 months until age 5, then annually thereafter. Genetic counselling is strongly recommended to discuss screening protocols and reproductive options.

2. How is the sample collected for this test in the UAE?

Our VIP Mobile Phlebotomy service sends a DHA-licensed phlebotomist to your home between 8 AM and 11 PM. The sample is 3–4 mL of venous blood collected under ISO-certified cold-chain conditions to ensure sample stability and diagnostic accuracy.

3. Is this test covered by insurance in the UAE?

We offer direct billing verification; many UAE insurers cover genetic testing when medically necessary. WhatsApp your policy details to +971 54 548 8731 for instant confirmation.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance & Accreditation

Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – genetic data privacy.
Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – digital health data security.
Federal Decree-Law No. 4 of 2016 on Medical Liability – patient consent and safety protocols.
ISO 9001:2015 Certified Facility (Cert: INT/EGQ/2509DA/3139).

All laboratory processing adheres to DHA/MOHAP standard nomenclature. Contact: +971 54 548 8731 (WhatsApp) | DHA Facility License: 1143

Clinical & Logistical Metadata

Test Name	RB1 Gene Hereditary Retinoblastoma Genetic Test (NGS)
Price (AED)	2,800
Turnaround Time	3–4 Weeks
Sample Type / Matrix	Peripheral Whole Blood (3–4 mL) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection
Methodology Used	Next-Generation Sequencing (Illumina™, 500x coverage)
ICD-10-CM Code	C69.20 (Malignant neoplasm of unspecified retina)
LOINC Code	21680-2 (RB1 gene mutation analysis in Blood by NGS)
DHA Facility License & Laboratory Address	DHA License: 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE \| Corporate Lab: DNA Labs UAE

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All reports reviewed by DHA-Certified physicians