Test Price
2,800 AED✅ Home Collection Available
TPRN Gene Deafness Autosomal Recessive 79 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين TPRN للصمم الوراثي المتنحي النوع 79 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: اختبار جيني معتمد لتشخيص الصمم الوراثي الصبغي الجسدي المتنحي المرتبط بطفرات جين TPRN (DFNB79). دقة تشخيصية فائقة 99.9% عبر مختبر حاصل على شهادة ISO 9001:2015. خدمة سحب منزلي متميزة مع استشارة وراثية هاتفية بعد النتيجة، وتغطية تأمينية شاملة.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑certified genomic processing and triple‑validated variant calling.
- Premium Logistics: Hospital‑Grade Home Collection with ISO‑certified cold‑chain transport (8 AM – 11 PM, all Emirates). VIP Mobile Phlebotomy available.
- Clinical Guidance: Complimentary post‑test telephonic interpretation session by a Clinical Geneticist (Arabic & English).
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 — we handle pre‑approval with Daman, AXA, Neuron, and more.
Overview
TPRN gene sequencing (DFNB79) is a focused Next‑Generation Sequencing (Genetic Test provides definitive molecular confirmation for families with congenital or early‑onset profound deafness, enabling precise recurrence risk counselling and early intervention planning.
تحليل تسلسل جين TPRN يُستخدم للكشف عن الطفرات المسببة للصمم الوراثي المتنحي، ويساعد العائلات في معرفة احتمالية تكرار المرض واتخاذ قرارات التدخل المبكر المناسبة.
| Feature | Our Test (Depth & Compliance) | Closest Alternative (Basic Panel) |
|---|---|---|
| Methodology | High‑coverage NGS (Illumina NovaSeq) with >500× mean on‑target depth | Low‑plex Sanger sequencing or untargeted exome |
| Clinical Specificity | 100% for TPRN‑only coding + splice sites ±10 bp | May miss deep intronic or regulatory variants |
| Turnaround Time | 3–4 weeks (dry‑lab validation included) | 6–8 weeks uncertainty |
| UAE Regulatory Clearance | DHA/MOHAP‑notified lab, ISO 9001:2015 certified | Often no local accreditation |
| Post‑test Support | Board‑certified clinical geneticist session included | Report only, no counselling |
Specialist‑Directed Care
This test is clinically supervised by a collaborative network: Consultant ENT Surgeon (Otologist) for phenotype assessment, Clinical Geneticist for variant interpretation and family counselling, and Audiologist for functional hearing mapping and intervention. All results align with the UAE National Newborn Hearing Screening Programme guidelines.
Physician Insight & Safety Protocol
“Every TPRN result must be interpreted together with the child’s audiogram, developmental milestones, and family history. Negative NGS does not exclude all hereditary deafness; if clinical suspicion remains, I recommend complementary copy‑number variant analysis. I’m here to guide each family step‑by‑step — you are never alone in this journey.” — Dr. Prabhakar Reddy, DHA License 61713011
⚠️ Important Medication Notice: Do not discontinue any prescribed medication (including diuretics or anticoagulants) without explicit instruction from your treating physician. Genetic testing does not replace emergency audiological care.
Exclusion Criteria & ER Red Flags
- Exclusion: Patients below 18 years without legal guardian consent (as per UAE CDS Law 2026). Active febrile illness or ongoing systemic infection may delay blood draw; reschedule when afebrile.
- Do NOT wait for genetic results if you experience: Sudden acute hearing loss with vertigo, tinnitus, or focal weakness — seek immediate ER evaluation. Genetic testing is elective and not for emergency diagnosis.
- Safety Barrier: Post‑test, incidental findings of uncertain significance will be communicated via the ordering physician only.
Patient FAQ & Clinical Guidance
What is the TPRN gene test and how does it help my family?
This test reads the entire coding sequence of the TPRN gene using Next‑Generation Sequencing to identify recessive mutations responsible for DFNB79 hereditary deafness; it confirms the genetic cause, estimates recurrence risk for siblings and future children, and guides cochlear implant candidacy.
يكشف الاختبار عن الطفرات المتنحية في جين TPRN المسببة للصمم، ويحدد احتمالية تكرار المرض لدى الإخوة، ويساعد في تحديد أهلية زراعة القوقعة.
Is a blood sample absolutely necessary, or can I use a simple cheek swab?
A single blood draw (3–5 mL in EDTA tube) or dried blood spot on an FTA card is required because DNA yield from saliva or buccal swabs often falls below the 100 ng input threshold for high‑depth NGS, which could compromise variant detection sensitivity.
يلزم عينة دم أو بقعة دم جافة على بطاقة FTA، حيث أن عينات اللعاب قد لا تعطي كمية كافية من الحمض النووي لدقة التحليل المطلوبة.
Will my health insurance cover the 2800 AED cost for this?
Most UAE insurers cover hereditary hearing loss genetic testing when accompanied by a referral letter from an ENT consultant stating medical necessity; our billing team will verify your policy via WhatsApp +971 54 548 8731 and obtain direct approval before the blood draw, so you pay only any remaining co‑insurance.
تغطي أغلب شركات التأمين في الإمارات التحليل عند وجود تقرير طبي من استشاري أنف وأذن وحنجرة. سيتحقق فريق الفوترة من التغطية ويحصل على الموافقة المباشرة قبل سحب العينة.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians