Test Price
2,800 AEDโ Home Collection Available
APC Gene Desmoid Disease Hereditary Genetic Test (NGS) in UAE โ 2800 AED โ DNA Labs UAE
Executive Summary & Core Metrics
This advanced genetic test utilises Next-Generation Sequencing (NGS) to comprehensively analyse the entire APC gene for pathogenic variants linked to hereditary desmoid disease and familial adenomatous polyposis (FAP). Designed for patients with a personal or family history of desmoid tumours or FAP, the test delivers actionable risk stratification to guide surveillance and preventive care.
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO-certified sequencing and bioinformatics pipeline.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM โ 11 PM.
- Clinical Guidance: Telephonic post-test consultation for result interpretation and next steps.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The test employs whole-gene Next-Generation Sequencing (NGS) to interrogate all coding exons, splice junctions, and deep intronic regions of the APC gene. This approach achieves superior analytical sensitivity compared to targeted hotspot panels, ensuring that rare and novel variants are captured.
| Parameter | Our Test (UAE Gold Standard) | Closest Alternative |
|---|---|---|
| Precision / Methodology | Full APC gene NGS (99.9% analytical sensitivity) | Targeted hotspot panels (limited to selected exons) |
| Coverage | All coding exons, splice sites, and deep intronic regions | Partial gene analysis; may miss rare/novel mutations |
| Turnaround Time | 3โ4 weeks (certified molecular report) | 4โ6 weeks with less comprehensive interpretation |
| UAE Compliance | Full compliance with Federal Decree-Law No. 45 of 2021 (PDPL) and Federal Law No. 2 of 2019 on health ICT | Variable; may lack dedicated genetic data protection |
Physician Insight & Safety Protocols
โThis NGS-based APC gene analysis provides crucial insight into hereditary desmoid and FAP risk. However, the result must always be interpreted within the full context of personal and family medical history, clinical examination, and radiological findings. A positive variant indicates predisposition โ it is not a diagnosis of active disease.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Important Clinical Advisory
This test provides a hereditary risk assessment only. Do not alter or discontinue any prescribed surveillance programme, medication, or surgical plan without consulting your specialist. Genetic results should complement, not replace, regular clinical follow-up.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals with acute febrile illness or recent blood transfusion (wait 4 weeks) โ may interfere with DNA quality and sequencing accuracy.
- Exclusion: Inability to provide informed consent or lack of a legal guardian for minors (per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Red Flag โ Seek Emergency Care: If you experience a rapidly growing abdominal mass, severe abdominal pain, or signs of intestinal obstruction, go to your nearest emergency department immediately, regardless of pending genetic results.
- Red Flag: New rectal bleeding or significant change in bowel habits in patients with known FAP warrants urgent endoscopic evaluation.
Patient FAQ & Clinical Guidance
1. What does the APC gene desmoid disease NGS test look for?
This test sequences the entire APC gene to identify harmful variants linked to desmoid tumours and familial adenomatous polyposis (FAP). It provides a precise risk assessment to guide personalised cancer surveillance and family cascade testing.
2. How should I prepare for the blood sample collection?
No fasting is required. Simply stay well-hydrated, and bring your Emirates ID and any previous genetic reports. Our mobile phlebotomist will collect a peripheral whole blood sample at your preferred location between 8 AM and 11 PM.
3. What do my results mean if a mutation is found, and what are the next steps?
A confirmed pathogenic APC variant indicates a hereditary predisposition requiring enhanced cancer surveillance (colonoscopy, desmoid screening) and family cascade testing for first-degree relatives. Your referring specialist will coordinate a tailored management plan based on the genetic finding.
4. How long does it take to receive the report, and how is it delivered?
The turnaround time is 3 to 4 weeks from sample receipt. The certified molecular report is delivered electronically via a secure portal, followed by a telephonic consultation with our genetics team to discuss the implications.
5. Is my genetic data protected under UAE law?
Yes. Your genetic information is handled in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 on health ICT. Data is encrypted, access-controlled, and never shared without your explicit consent.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates in strict compliance with UAE federal privacy and health data protection frameworks. All genetic testing procedures adhere to:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ governing the collection, processing, and storage of personal and genetic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ regulating health information systems and digital data security.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ ensuring patient safety, informed consent, and clinical accountability.
Patients retain full rights to access, rectify, and request deletion of their genetic data. All results are shared via encrypted channels with explicit consent only.
Clinical & Logistical Metadata
| Test Name | APC Gene Desmoid Disease Hereditary Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 weeks |
| Sample Type / Matrix | Peripheral whole blood (3โ5 mL in EDTA tube) |
| Methodology Used | Next-Generation Sequencing (NGS) โ whole APC gene, all coding exons, splice sites, and deep intronic regions |
| ICD-10-CM Code | Z15.09, D48.1, M72.6 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians