Test Price
2,800 AED✅ Home Collection Available
RNASEL Gene Hereditary Prostate Cancer Type 1 – Genetic Test | 2800 AED | DHA-Certified
Executive Summary & Core Metrics
Diagnostic Accuracy: 99.9% Sensitivity via ISO 9001:2015 Certified NGS Workflow – DHA/MOHAP approved.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM–11 PM) with ISO-certified transport.
Post-Test Clinical Guidance: Telephonic result interpretation by a DHA-licensed Genetic Counsellor.
Insurance Made Easy: Direct Billing Verification via WhatsApp at +971 54 548 8731.
This advanced genetic test performs whole-exome sequencing of the RNASEL gene to identify pathogenic variants linked to hereditary prostate cancer type 1 (HPC1). It empowers at-risk individuals with actionable insights for personalised surveillance and early intervention.
Test Overview & Methodology
This next-generation sequencing (NGS) test examines the entire coding region of the RNASEL gene for pathogenic variants, including copy-number analysis. It is designed for individuals with a strong family history of early-onset prostate cancer or known RNASEL mutations.
| Feature | Our RNASEL Test (NGS) | Closest Alternative (Targeted Panel) |
|---|---|---|
| Methodology | Full-Gene Sequencing + Copy-Number Analysis (NGS) | Select Exon Targets only |
| Diagnostic Sensitivity | >99.9% (Clinically validated, DHA-compliant) | ~85–90% (may miss deep intronic mutations) |
| Turnaround Time | 3–4 Weeks (from sample arrival) | 4–6 Weeks |
| Pre- & Post-Test Counselling | Included (DHA Genetic Counsellor) | Often not bundled |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
“A positive RNASEL result indicates elevated lifetime risk for prostate cancer, not a definitive diagnosis. It should be interpreted within the context of comprehensive family history and clinical findings. Always involve a specialised genetics team before altering surveillance or treatment strategies. Do not discontinue any prescribed medication without consulting your physician.”
Clinical Advisory Notice
Medication Continuation Important
Do not discontinue any prescribed medication (including anti-androgens, 5-alpha reductase inhibitors, or dietary supplements) without consulting your treating physician. Genetic test results should inform, not replace, medical management.
Safety Exclusion Criteria & Emergency Red Flags
- Do NOT proceed with sample collection if you have received a blood transfusion within the last 2 weeks – this can obscure germline DNA analysis.
- If you are on high-dose anticoagulation (e.g., Warfarin, Heparin), inform the phlebotomist before the draw to minimise bruising risk.
- ER Red Flag: If you experience severe chest pain, suicidal ideation, or panic attacks after receiving genetic results, seek emergency care immediately.
- Minors (under 18): Genetic testing for hereditary cancer syndromes requires informed consent per Federal Decree-Law No. 4 of 2016 on Medical Liability and independent genetic counselling.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of RNASEL gene testing?
Snippet-optimised answer: RNASEL gene testing identifies hereditary mutations linked to increased prostate cancer risk, guiding early screening and personalised risk-reduction strategies.
The result stratifies patients into high-risk surveillance programmes (e.g., annual PSA + MRI starting at age 40) and can trigger cascade testing for at-risk relatives.
2. Who should consider this genetic test?
Snippet-optimised answer: Individuals with a strong family history of early-onset prostate cancer (multiple first-degree relatives diagnosed before age 50) or known RNASEL mutations in the family.
Carrier women may also be tested as they can pass the mutation to their sons. Pre-test genetic counselling is mandatory.
3. How is the sample collected and what is the turnaround time?
Snippet-optimised answer: A simple blood draw or buccal swab is collected at home by a DHA-licensed phlebotomist; results are delivered in 3–4 weeks.
Samples are transported at 2–8 °C to our ISO-certified laboratory. Pre-genetic counselling (pedigree drawing) is mandatory and can be performed via telehealth.
UAE Regulatory & Data Privacy Adherence
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): All genetic data is processed exclusively on secure, in-country servers with end-to-end encryption.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: Ensures secure electronic health records and telehealth counselling.
- Federal Decree-Law No. 4 of 2016 on Medical Liability: Mandates informed consent, qualified genetic counselling, and strict confidentiality for all genetic tests.
- ISO 9001:2015 – Certificate INT/EGQ/2509DA/3139 (Quality Management System for Molecular Diagnostics).
- Facility License: DHA Facility License Number 1143; Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | RNASEL Gene Hereditary Prostate Cancer Type 1 – Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks from sample arrival |
| Sample Type / Matrix | Peripheral blood (whole blood) or buccal swab |
| Methodology Used | Next-Generation Sequencing (NGS) Full-Gene + Copy-Number Analysis |
| ICD-10-CM Code | Z80.43 |
| LOINC Code | 80814-8 |
| DHA Facility License & Laboratory Address | License 1143 – DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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