Test Price
4,800 AEDโ Home Collection Available
HBOC Extended Panel (32 Genes) in UAE | 4800 AED | Genetic Risk Assessment
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Complimentary post-test telephonic clinical guidance by DHA-licensed medical genetics consultant for result interpretation.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The HBOC Extended Panel evaluates 32 genes associated with hereditary breast and ovarian cancer using next-generation sequencing (NGS). This test provides lifetime risk stratification, enabling personalised surveillance or prophylactic strategies in accordance with NCCN and ESMO guidelines.
| Feature | Our HBOC Extended Panel (32 Genes) | Closest Alternative (Single-Gene BRCA1/2) |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) โ Illumina NovaSeq X equivalent | Sanger Sequencing / targeted PCR |
| Gene Coverage | 32 genes including BRCA1, BRCA2, PALB2, ATM, CHEK2, RAD51C/D, TP53 and more | BRCA1 and BRCA2 only |
| Turnaround Time | 4โ5 weeks | 2โ3 weeks |
| Diagnostic Sensitivity | 99.9% (validation in high-risk cohorts) | ~95% for coding variants, misses large rearrangements |
| Price in UAE | 4800 AED | โ 2000 โ 2500 AED |
| Clinical Utility | Comprehensive hereditary cancer risk assessment; guides NCCN/ESMO management | Limited; additional panels often required after negative result |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403) explains:
โThis expanded panel is a precision risk-assessment toolโit is not a diagnostic test for active cancer. A negative result does not guarantee absence of future malignancy, and a positive finding must be discussed with an oncologist or genetic counsellor to design a tailored surveillance or prevention plan. All testing adheres to Federal Decree-Law No. 4 of 2016 on Medical Liability regarding patient consent and clinical safety.โ
Medication and Prescription Advisory
- Medication Warning: Do not discontinue prescribed medication without consulting your doctor; sudden cessation may pose severe risks.
- Prescription Mandatory: A valid prescription from a DHA-licensed physician is required to proceed with this test. This panel is not intended for surgery clearance, pregnancy evaluation, or travel fitness certificates.
Patient Exclusion Criteria
- Minors: Genetic testing for individuals under 18 is regulated under UAE personal data protection laws; legal guardian consent and documented clinical necessity are mandatory.
- Emergency Red Flags: If you currently experience breast lumps, abnormal vaginal bleeding, persistent pelvic pain, or unexplained weight loss, seek urgent clinical evaluation before pursuing elective genetic screening.
Patient FAQ & Clinical Guidance
1. What is the HBOC Extended Panel and who should consider it?
Direct Answer: A comprehensive genetic test evaluating 32 genes linked to hereditary breast and ovarian cancer. It is recommended for individuals with a strong family history of these cancers, multiple affected relatives, early age of onset, or known familial mutations.
The panel identifies pathogenic variants that significantly increase lifetime cancer risk, guiding personalised screening (MRI, mammogram), risk-reducing surgeries, and cascade testing for relatives. Results are interpreted according to ACMG/AMP standards.
2. How is the test performed and what is the turnaround time?
Direct Answer: A simple peripheral blood sample is collected by our VIP mobile phlebotomy team and analysed using next-generation sequencing. Definitive results are delivered within 4 to 5 weeks.
The sample is transported under continuous cold-chain monitoring to our ISO-certified laboratory. After sequencing, expert bioinformaticians and molecular geneticists interpret the data. Results include variant classification and lifetime risk estimation, communicated through a secure portal with complimentary telephonic guidance.
3. Is my genetic data confidential and how will I receive interpretation?
Direct Answer: All genetic data is encrypted and protected under UAE Personal Data Protection Law. A secure report is delivered with complimentary clinical guidance from a DHA-licensed genetic counsellor.
Your sample and results are de-identified and stored in compliance with Federal Decree-Law No. 45 of 2021 (PDPL) and Federal Law No. 2 of 2019 concerning health information technology. The counsellor walks you through actionable recommendations and coordinates with your referring physician. Direct billing and insurance preapproval are available via WhatsApp at +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This service strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability for patient consent. All processing is conducted under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). The laboratory operates under DHA Facility License No. 1143.
Clinical & Logistical Metadata
| Test Name | HBOC Extended Panel (32 Genes) |
| Price (AED) | 4,800 AED |
| Turnaround Time | 4โ5 weeks from sample receipt |
| Sample Type / Matrix | Peripheral whole blood (EDTA tube) โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AMโ11 PM |
| Methodology Used | Next-Generation Sequencing (NGS) โ Illumina NovaSeq X equivalent with enhanced bioinformatic analysis for large rearrangements |
| ICD-10-CM Code | Z15.01, Z15.02, Z84.81 |
| LOINC Code | 81776-9 |
| DHA Facility License & Address | License 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians